Zobrazeno 1 - 10
of 382
pro vyhledávání: '"Anne Durandy"'
UnAIDed Class Switching in Activated B-Cells Reveals Intrinsic Features of a Self-Cleaving IgH Locus
Autor:
Iman Dalloul, Brice Laffleur, Zeinab Dalloul, Batoul Wehbi, Florence Jouan, Baptiste Brauge, Paco Derouault, Jeanne Moreau, Sven Kracker, Alain Fischer, Anne Durandy, Sandrine Le Noir, Michel Cogné
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Activation-induced deaminase (AID) is the major actor of immunoglobulin (Ig) gene diversification in germinal center B-cells. From its first description, it was considered as mandatory for class switch recombination (CSR), and this discovery initiate
Externí odkaz:
https://doaj.org/article/1d9f8414d03043ce9311e61b783fb76a
Autor:
Nidia Moreno-Corona, Loïc Chentout, Lucie Poggi, Romane Thouenon, Cecile Masson, Melanie Parisot, Lou Le Mouel, Capucine Picard, Isabelle André, Marina Cavazzana, Laurence Perrin, Anne Durandy, Saba Azarnoush, Sven Kracker
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Activated PI3-kinase-δ syndrome 2 (APDS2) is caused by autosomal dominant mutations in the PIK3R1 gene encoding the p85α, p55α, and p50α regulatory subunits. Most diagnosed APDS2 patients carry mutations affecting either the splice donor or splic
Externí odkaz:
https://doaj.org/article/7550814d44e942aba4bf0bf01ddc33f7
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Autosomal dominant gain-of-function mutations in the PIK3CD gene encoding the catalytic subunit p110δ of phosphoinositide 3-kinase-δ (PI3K-δ) or autosomal dominant loss-of-function mutations in the PIK3R1 gene encoding the p85α, p55α and p50α r
Externí odkaz:
https://doaj.org/article/816dfad0f0f34c8fab227a56481d1c9c
Autor:
Iman Dalloul, François Boyer, Zeinab Dalloul, Amandine Pignarre, Gersende Caron, Thierry Fest, Fabrice Chatonnet, Céline Delaloy, Anne Durandy, Robin Jeannet, Emilie Lereclus, Hend Boutouil, Jean-Claude Aldigier, Sophie Péron, Sandrine Le Noir, Jeanne Cook-Moreau, Michel Cogné
Publikováno v:
PLoS Genetics, Vol 15, Iss 6, p e1007721 (2019)
B-cell activation yields abundant cell death in parallel to clonal amplification and remodeling of immunoglobulin (Ig) genes by activation-induced deaminase (AID). AID promotes affinity maturation of Ig variable regions and class switch recombination
Externí odkaz:
https://doaj.org/article/b008f55c724e43988bbb8e81994f41ac
Autor:
Romane Thouenon, Loïc Chentout, Nidia Moreno-Corona, Lucie Poggi, Emilia Puig Lombardi, Benedicte Hoareau, Yohann Schmitt, Chantal Lagresle-Peyrou, Jacinta Bustamante, Isabelle André, Marina Cavazzana, Anne Durandy, Jean-Laurent Casanova, Lionel Galicier, Jehane Fadlallah, Alain Fischer, Sven Kracker
Publikováno v:
Journal of Experimental Medicine. 220
Here, we report on a heterozygous interferon regulatory factor 4 (IRF4) missense variant identified in three patients from a multigeneration family with hypogammaglobulinemia. Patients’ low blood plasmablast/plasma cell and naïve CD4 and CD8 T cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e06f7594419e4e06efb0ae90fc7b19c9
https://doi.org/10.1084/jem.20221292
https://doi.org/10.1084/jem.20221292
Autor:
Lucie Heurtier, Hicham Lamrini, Loïc Chentout, Marie-Céline Deau, Amine Bouafia, Jérémie Rosain, Jean-Marc Plaza, Mélanie Parisot, Benoit Dumont, Delphine Turpin, Etienne Merlin, Despina Moshous, Nathalie Aladjidi, Bénédicte Neven, Capucine Picard, Marina Cavazzana, Alain Fischer, Anne Durandy, Jean-Louis Stephan, Sven Kracker
Publikováno v:
Haematologica, Vol 102, Iss 7 (2017)
Externí odkaz:
https://doaj.org/article/a8939c0c71d048bf91d07da9e764faa6
Autor:
Hassan Abolhassani, Reza Yazdani, Anne Durandy, Parisa Amirifar, Mohammad Reza Ranjouri, Gholamreza Azizi, Alessandro Plebani, Asghar Aghamohammadi, Lennart Hammarström, Vassilios Lougaris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3283a2476674059f93aaebb9bf7aacbe
https://doi.org/10.1111/pai.13589/v2/response1
https://doi.org/10.1111/pai.13589/v2/response1
Autor:
Vincent Caval, Bianka Mussil, Jean-Pierre Vartanian, Anne Durandy, Simon Wain-Hobson, Rodolphe Suspène
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports, 2019, 9 (1), pp.3109. ⟨10.1038/s41598-019-39245-8⟩
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.3109. ⟨10.1038/s41598-019-39245-8⟩
Scientific Reports
Scientific Reports, 2019, 9 (1), pp.3109. ⟨10.1038/s41598-019-39245-8⟩
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.3109. ⟨10.1038/s41598-019-39245-8⟩
International audience; Human cells are stressed by numerous mechanisms that can lead to leakage of mitochondrial DNA (mtDNA) to the cytoplasm and ultimately apoptosis. this agonist DNA constitutes a danger to the cell and is counteracted by cytoplas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b84ef409b95357fb99b40a740d4ebe1
http://link.springer.com/article/10.1038/s41598-019-39245-8
http://link.springer.com/article/10.1038/s41598-019-39245-8
Autor:
Tomohiro Morio, Tsubasa Okano, Yujin Sekinaka, Eri Endo, Katsuyuki Hanabusa, Ikuya Tsuge, Shiann Tarng Jou, Masataka Ishimura, Hsin-Hui Yu, Yoshihiro Maruo, Tomiko Kimoto, Tomoaki Kunitsu, Hiroshi Yagasaki, Masami Inoue, Kenichi Yoshida, Yuki Tsujita, Taizo Wada, Kohsuke Imai, Kyoko Suzuki, Seiji Kojima, Sven Kracker, Tetsuzo Tauchi, Yuko Hashimoto, Takehiro Takashima, Yuzaburo Inoue, Toru Uchiyama, Hidetoshi Takada, Kenichi Honma, Motohiro Kato, Masakazu Nagahori, Takashi Kaneko, Yoshiaki Shikama, Naohiko Moriguchi, Tomoko Waragai, Daiei Kojima, Haruka Hiroki, Tamaki Kato, Kanako Mitsui-Sekinaka, Keisuke Tanaka, Anne Durandy, Yuki Bando, Hideki Muramatsu, Kazuhiro Tasaki, Seishi Ogawa, Hirokazu Kanegane, Fuminori Iwasaki, Shigeaki Nonoyama, Tzu Wen Yeh, Chikako Kamae, Toshihiko Shirakawa, Osamu Suzuki, Tomoyo Matsubara, Hideki Sano, Yuki Yuza, Osamu Ohara, Noriko Mitsuiki
Publikováno v:
Journal of Allergy and Clinical Immunology. 143:266-275
Background Activated phosphatidylinositol-3-OH kinase δ syndrome type 1 (APDS1) is a recently described primary immunodeficiency syndrome characterized by recurrent respiratory tract infections, lymphoid hyperplasia, and Herpesviridae infections cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bb44153e5e8d631309e74864a023dc5
https://doi.org/10.1016/j.jaci.2018.04.032
https://doi.org/10.1016/j.jaci.2018.04.032