Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Anne Desmazières"'
Autor:
Vasiliki Pantazou, Thomas Roux, Vanessa Oliveira Moreira, Catherine Lubetzki, Anne Desmazières
Publikováno v:
Life, Vol 11, Iss 3, p 231 (2021)
Multiple sclerosis (MS) is a complex central nervous system inflammatory disease leading to demyelination and associated functional deficits. Though endogenous remyelination exists, it is only partial and, with time, patients can enter a progressive
Externí odkaz:
https://doaj.org/article/25c8ce56cc194c8b80037a9a48f4a8ea
Autor:
Amandine Duchesne, Anne Vaiman, Magali Frah, Sandrine Floriot, Sabrina Legoueix-Rodriguez, Anne Desmazières, Sébastien Fritz, Christian Beauvallet, Olivier Albaric, Eric Venot, Maud Bertaud, Romain Saintilan, Raphaël Guatteo, Diane Esquerré, Julien Branchu, Anaïs Fleming, Alexis Brice, Frédéric Darios, Jean-Luc Vilotte, Giovanni Stevanin, Didier Boichard, Khalid Hamid El Hachimi
Publikováno v:
PLoS Genetics, Vol 14, Iss 8, p e1007550 (2018)
Hereditary spastic paraplegias (HSPs) are clinically and genetically heterogeneous human neurodegenerative diseases. Amongst the identified genetic causes, mutations in genes encoding motor proteins such as kinesins have been involved in various HSP
Externí odkaz:
https://doaj.org/article/19f03c95bd66498a8b31753d5b4988c1
Autor:
Thomas Roux, Vasiliki Pantazou, Anne Desmazières, Vanessa Oliveira Moreira, Catherine Lubetzki
Publikováno v:
Life
Life, Vol 11, Iss 231, p 231 (2021)
Life, MDPI, 2021, 11 (3), pp.231. ⟨10.3390/life11030231⟩
Life, 2021, 11 (3), pp.231. ⟨10.3390/life11030231⟩
Life, Vol 11, Iss 231, p 231 (2021)
Life, MDPI, 2021, 11 (3), pp.231. ⟨10.3390/life11030231⟩
Life, 2021, 11 (3), pp.231. ⟨10.3390/life11030231⟩
International audience; Multiple sclerosis (MS) is a complex central nervous system inflammatory disease leading to demyelination and associated functional deficits. Though endogenous remyelination exists, it is only partial and, with time, patients
Autor:
L. Richard, Melina Thetiot, Thomas Roux, Marie-Stéphane Aigrot, Elisa Mazuir, François-Xavier Lejeune, Jean-Michel Vallat, Anne Desmazières, Remi Ronzano, Catherine Lubetzki
Microglia, the resident immune cells of the central nervous system, are key players in healthy brain homeostasis and plasticity. In neurological diseases, such as Multiple Sclerosis, activated microglia either promote tissue damage or favor neuroprot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ef9d8618b650408273d74c2b0b93677
https://doi.org/10.1101/2020.09.02.279562
https://doi.org/10.1101/2020.09.02.279562
Publikováno v:
Nature reviews. Neurology. 16(8)
Saltatory conduction of action potentials along myelinated axons depends on the nodes of Ranvier - small unmyelinated axonal domains where voltage-gated sodium channels are concentrated. Our knowledge of the complex molecular composition of these axo
Autor:
François-Xavier Lejeune, Anne-Laure Dubessy, Quentin Rappeneau, Sean A. Freeman, Julien Tailleur, Catherine Lubetzki, Nathalie Sol-Foulon, Anne Desmazières, Marie-Stéphane Aigrot, Melina Thetiot, Thomas Roux
Publikováno v:
Glia
Glia, Wiley, 2020, 68 (9), pp.1891-1909. ⟨10.1002/glia.23812⟩
Glia, 2020, 68 (9), pp.1891-1909. ⟨10.1002/glia.23812⟩
Glia, Wiley, 2020, 68 (9), pp.1891-1909. ⟨10.1002/glia.23812⟩
Glia, 2020, 68 (9), pp.1891-1909. ⟨10.1002/glia.23812⟩
SUMMARYIn vertebrates, fast saltatory conduction along myelinated axons relies on the node of Ranvier. How nodes assemble on CNS neurons is not yet fully understood. We recently highlighted that clusters similar to nodes can form prior to myelin depo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfefac9c63aee50bbcfe0dca6b528b8c
Publikováno v:
Journal of visualized experiments : JoVE. (145)
In the nervous system, myelin is a complex membrane structure generated by myelinating glial cells, which ensheathes axons and facilitates fast electrical conduction. Myelin alteration has been shown to occur in various neurological diseases, where i
Autor:
Raphaël Guatteo, Diane Esquerre, Sabrina Legoueix-Rodriguez, Maud Bertaud, Anaïs Fleming, Julien Branchu, Christian Beauvallet, Romain Saintilan, Alexis Brice, Amandine Duchesne, Anne Vaiman, Frédéric Darios, Anne Desmazières, Giovanni Stevanin, Sandrine Floriot, Magali Frah, Olivier Albaric, Eric Venot, Khalid Hamid El Hachimi, Sébastien Fritz, Jean-Luc Vilotte, Didier Boichard
Publikováno v:
PLoS Genetics
PLoS Genetics, Public Library of Science, 2018, 14 (8), pp.1-25. ⟨10.1371/journal.pgen.1007550⟩
Plos Genetics 8 (14), 1-25. (2018)
PLoS Genetics, 2018, 14 (8), pp.1-25. ⟨10.1371/journal.pgen.1007550⟩
PLoS Genetics, Vol 14, Iss 8, p e1007550 (2018)
PLoS Genetics, Public Library of Science, 2018, 14 (8), pp.1-25. ⟨10.1371/journal.pgen.1007550⟩
Plos Genetics 8 (14), 1-25. (2018)
PLoS Genetics, 2018, 14 (8), pp.1-25. ⟨10.1371/journal.pgen.1007550⟩
PLoS Genetics, Vol 14, Iss 8, p e1007550 (2018)
Hereditary spastic paraplegias (HSPs) are clinically and genetically heterogeneous human neurodegenerative diseases. Amongst the identified genetic causes, mutations in genes encoding motor proteins such as kinesins have been involved in various HSP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::422ecf5137fe6992d8957c0ab7e85fc4
https://hal.inrae.fr/hal-02624522
https://hal.inrae.fr/hal-02624522
Publikováno v:
Methods in Molecular Biology ISBN: 9781493978618
Immunochemistry (immunocytochemistry for cells and immunohistochemistry for tissues) is a method used to label specific antigens, based on highly specific antibody-epitope interactions. The resulting labeling can be visualized and imaged through micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::effc6f3a3e38d78ba9c0b08c2d00faf4
https://doi.org/10.1007/978-1-4939-7862-5_2
https://doi.org/10.1007/978-1-4939-7862-5_2
Publikováno v:
Multiple Sclerosis Journal. 18:133-137
How axonal damage, a major prognostic factor of multiple sclerosis disability progression, is induced, is likely to be multifactorial. Whereas axonal injury has been identified as a consequence of myelin loss, the possibility of an additional direct