Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Anne Denys"'
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 4, Pp 752-758 (2005)
We elucidated the mechanisms of action of two n-3 PUFAs, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), in Jurkat T-cells. Both DHA and EPA were principally incorporated into phospholipids in the following order: phosphatidylcholine < ph
Externí odkaz:
https://doaj.org/article/f588bc13e00840cf80ff1d696ad90b1b
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 12, Pp 2015-2020 (2001)
This study was conducted on human Jurkat T cell lines to elucidate the role of EPA and DHA, n-3 PUFA, in the modulation of two mitogen-activated protein (MAP) kinases, that is, extracellular signal-regulated kinases 1 and 2 (ERK1 and ERK2). The n-3 P
Externí odkaz:
https://doaj.org/article/465a88df70764169be1ae1fa2e15f636
Autor:
Olivier Schischmanoff, Gaëlle Clavel, Delphine Lemeiter, Luca Semerano, Marie-Christophe Boissier, Anne Denys
Publikováno v:
Journal of Cellular and Molecular Medicine
Cardiovascular disease (CVD) is a major cause of morbidity and mortality in rheumatoid arthritis (RA). There are limited experimental data on vascular involvement in arthritis models. To study the link between CVD and inflammation in RA, we developed
Autor:
Jérôme Biton, Natacha Bessis, MC Boissier, Anne Denys, Delphine Lemeiter, Allan Thiolat, M. Petit, Roxane Hervé, Didier Lutomski
Publikováno v:
Cytokine. 69:87-93
Interleukin (IL)-35 was initially described as an immunosuppressive cytokine specifically produced by CD4(+)FoxP3(+) regulatory T cells (Treg). Since Treg play a major role in autoimmunity control and protect from inflammation, we aimed at evaluating
Autor:
Anne Denys, Marie-Christophe Boissier, Géraldine Falgarone, Jérôme Biton, Eric Assier, Natacha Bessis
Publikováno v:
Joint Bone Spine. 76:10-14
Modulation of the T-cell response depends chiefly on regulatory T cells (Treg), which express CD4 and CD25. Some Treg cells are present naturally, whereas others are induced in response to antigens. The immunomodulating effects of Treg cells are medi
Autor:
Anne Denys, Marie-Christophe Boissier, Eric Assier, Natacha Bessis, Jérôme Biton, Géraldine Falgarone
Publikováno v:
Revue du Rhumatisme. 76:10-15
Resume La modulation de la reponse lymphocytaire T repose en grande partie sur une population de lymphocytes T appelee T regulateurs (Treg), dont le phenotype est CD4+CD25++. Il existe des lymphocytes Treg naturels et des lymphocytes T induits en rep
Autor:
Jean-François Zagury, Laure Delavallée, Géraldine Falgarone, Anne Denys, Marie-Christophe Boissier, S. Muller, Eric Assier, Natacha Bessis
Publikováno v:
Annals of Medicine
Annals of Medicine, Taylor & Francis, 2008, 40 (5), pp.343-51. ⟨10.1080/07853890801995298⟩
Annals of Medicine, Taylor & Francis, 2008, 40 (5), pp.343-51. ⟨10.1080/07853890801995298⟩
Most autoimmune diseases have an unknown etiology, but all involve cytokines cascade in their development. At the present time, several cytokines have been identified as major targets in various autoimmune diseases, involving the development of monoc
Autor:
N Bessis, Bernard Bizzini, D. Zagury, Anne Denys, Laure Delavallée, H. Le Buanec, Eric Assier, MC Boissier
Publikováno v:
Annals of the Rheumatic Diseases. 67:1332-1338
Objective: To evaluate the effect in mice with arthritis of active anti-TNFα immunotherapy based on a keyhole limpet hemocyanin-human TNFα heterocomplex (hTNFα kinoid or TNFK) adjuvanted in incomplete Freund adjuvant. Immunotherapy was evaluated a
Autor:
Florence Apparailly, Pascal Bigey, MC Boissier, Natacha Bessis, Anne Denys, Daniel Scherman, C. Bloquel
Publikováno v:
The Journal of Gene Medicine. 9:986-993
Background Anti-inflammatory gene therapy is promising in inflammatory diseases such as rheumatoid arthritis (RA). We have previously demonstrated that intra-muscular (i.m.) electrotransfer (ET) of plasmids encoding three different human tumor necros
Publikováno v:
Biochimie. 88:1823-1829
The aim of this study was to determine in vitro whether lead has a direct cytotoxic effect on the female gamete or through its surrounding somatic cells. We had previously demonstrated that it partly accumulates in the mouse ovary and induces follicl