Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Anne Dejean"'
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102573- (2023)
Summary: The field of stem cell-based embryo-like models is rapidly evolving, providing in vitro models of in utero stages of mammalian development. Here, we detail steps to first establish adherent spheroids composed of three cell types from mouse e
Externí odkaz:
https://doaj.org/article/846f974bafb440d697d851720e28bb13
Autor:
Jack-Christophe Cossec, Tatiana Traboulsi, Sébastien Sart, Yann Loe-Mie, Manuel Guthmann, Ivo A. Hendriks, Ilan Theurillat, Michael L. Nielsen, Maria-Elena Torres-Padilla, Charles N. Baroud, Anne Dejean
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112380- (2023)
Summary: Recent advances in synthetic embryology have opened new avenues for understanding the complex events controlling mammalian peri-implantation development. Here, we show that mouse embryonic stem cells (ESCs) solely exposed to chemical inhibit
Externí odkaz:
https://doaj.org/article/09154f7e8f0849ac8de3d952614588ea
Autor:
Jiang Zhang, Stéphanie Le Gras, Kevin Pouxvielh, Fabrice Faure, Lucie Fallone, Nicolas Kern, Marion Moreews, Anne-Laure Mathieu, Raphaël Schneider, Quentin Marliac, Mathieu Jung, Aurore Berton, Simon Hayek, Pierre-Olivier Vidalain, Antoine Marçais, Garvin Dodard, Anne Dejean, Laurent Brossay, Yad Ghavi-Helm, Thierry Walzer
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Natural Killer cell development is controlled by two related transcription factors, Eomes and T-bet. Authors show here that while the two factors share a large proportion of their target genes, they regulate distinct developmental processes by differ
Externí odkaz:
https://doaj.org/article/0a1b6ee2a9a04c48998d4f888c12b930
Autor:
Müge Ogrunc, Ricardo Ivan Martinez-Zamudio, Paul Ben Sadoun, Gregory Dore, Helene Schwerer, Philippe Pasero, Jean-Marc Lemaitre, Anne Dejean, Oliver Bischof
Publikováno v:
Cell Reports, Vol 34, Iss 8, Pp 108786- (2021)
Externí odkaz:
https://doaj.org/article/fc873390f8e241179b30e691ceb8157f
Autor:
Ilan Theurillat, Ivo A. Hendriks, Jack-Christophe Cossec, Alexandra Andrieux, Michael L. Nielsen, Anne Dejean
Publikováno v:
Cell Reports, Vol 33, Iss 1, Pp 108251- (2020)
Externí odkaz:
https://doaj.org/article/85bce2c2cf624d1d914a129a6a752c8c
Autor:
Xiao Ding, Aibo Wang, Xiaopeng Ma, Maud Demarque, Wei Jin, Huawei Xin, Anne Dejean, Chen Dong
Publikováno v:
Cell Reports, Vol 16, Iss 4, Pp 1055-1066 (2016)
Foxp3-expressing regulatory T (Treg) cells are essential for immune tolerance; however, the molecular mechanisms underlying Treg cell expansion and function are still not well understood. SUMOylation is a protein post-translational modification chara
Externí odkaz:
https://doaj.org/article/d40c87a60c224771bcadc91b5894c7d6
Autor:
Müge Ogrunc, Ricardo Ivan Martinez-Zamudio, Paul Ben Sadoun, Gregory Dore, Helene Schwerer, Philippe Pasero, Jean-Marc Lemaitre, Anne Dejean, Oliver Bischof
Publikováno v:
Cell Reports, Vol 15, Iss 7, Pp 1401-1411 (2016)
Summary: Oncogene-induced senescence (OIS) is a potent barrier for the transformation of pre-cancerous cells. The molecular pathways involved in the execution of OIS are still incompletely understood, but they include chronic DNA damage signaling and
Externí odkaz:
https://doaj.org/article/7b3a6870ecc04a49a49943dec5dc42ee
Autor:
Pierre Lapaquette, Sabrina Fritah, Nouara Lhocine, Alexandra Andrieux, Giulia Nigro, Joëlle Mounier, Philippe Sansonetti, Anne Dejean
Publikováno v:
eLife, Vol 6 (2017)
Disruption of the sumoylation/desumoylation equilibrium is associated with several disease states such as cancer and infections, however the mechanisms regulating the global SUMO balance remain poorly defined. Here, we show that infection by Shigella
Externí odkaz:
https://doaj.org/article/6d3352ef2a5a4b7cbdb31b4aafd0e698
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102957 (2014)
Gene silencing by small RNAs has emerged as a powerful post-transcriptional regulator of gene expression, however processes underlying regulation of the small RNA pathway in vivo are still largely elusive. Here, we identified sumoylation as a novel p
Externí odkaz:
https://doaj.org/article/6073e28bb3254476b2b21b7cfcc65a68
Autor:
Agnès Marchio, Stéphane Bertani, Teresa Rojas Rojas, Franco Doimi, Benoît Terris, Eric Deharo, Anne Dejean, Eloy Ruiz, Pascal Pineau
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114912 (2014)
Hepatocellular carcinoma usually afflicts individuals in their later years following longstanding liver disease. In Peru, hepatocellular carcinoma exists in a unique clinical presentation, which affects patients around age 25 with a normal, healthy l
Externí odkaz:
https://doaj.org/article/d51f6c6323b84cfea8e389ef9ef4cb41