Zobrazeno 1 - 10
of 271
pro vyhledávání: '"Anne Cooke"'
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 8, Pp 1362-1372 (2019)
Abstract Objective Despite progress in treating relapsing multiple sclerosis (MS), effective inhibition of nonrelapsing progressive MS is an urgent, unmet, clinical need. Animal models of MS, such as experimental autoimmune encephalomyelitis (EAE), p
Externí odkaz:
https://doaj.org/article/c433fd89108b4b11a8e6fffbe7672209
Autor:
Robert A. Benson, Fabien Garcon, Asha Recino, John R. Ferdinand, Menna R. Clatworthy, Herman Waldmann, James M. Brewer, Klaus Okkenhaug, Anne Cooke, Paul Garside, Maja Wållberg
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
We present a novel and readily accessible method facilitating cellular time-resolved imaging of transplanted pancreatic islets. Grafting of islets to the mouse ear pinna allows non-invasive, in vivo longitudinal imaging of events in the islets and en
Externí odkaz:
https://doaj.org/article/96636762e3204d01b5265dcbd95c7c77
Autor:
Alessandra De Riva, Maja Wållberg, Francesca Ronchi, Richard Coulson, Andrew Sage, Lucy Thorne, Ian Goodfellow, Kathy D McCoy, Miyuki Azuma, Anne Cooke, Robert Busch
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0181964 (2017)
Microbes, including viruses, influence type 1 diabetes (T1D) development, but many such influences remain undefined. Previous work on underlying immune mechanisms has focussed on cytokines and T cells. Here, we compared two nonobese diabetic (NOD) mo
Externí odkaz:
https://doaj.org/article/c98b1959c4fd46a5883ababcc51562fa
Autor:
James Doonan, David Thomas, Michelle H. Wong, Hazel J. Ramage, Lamyaa Al-Riyami, Felicity E. Lumb, Kara S. Bell, Karen J. Fairlie-Clarke, Colin J. Suckling, Kathrin S. Michelsen, Hui-Rong Jiang, Anne Cooke, Margaret M. Harnett, William Harnett
Publikováno v:
Molecules, Vol 23, Iss 10, p 2669 (2018)
Parasitic helminths and their isolated secreted products show promise as novel treatments for allergic and autoimmune conditions in humans. Foremost amongst the secreted products is ES-62, a glycoprotein derived from Acanthocheilonema viteae, a filar
Externí odkaz:
https://doaj.org/article/d5805fddbabc4db1868d1305e8b5be66
Autor:
Ariana Barbera Betancourt, Juliet L Emery, Asha Recino, F Susan Wong, Anne Cooke, Klaus Okkenhaug, Maja Wallberg
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146516 (2016)
Type 1 diabetes is caused by the destruction of insulin producing beta cells by the immune system. The p110δ isoform of PI3K is expressed primarily in cells of haematopoietic origin and the catalytic activity of p110δ is important for the activatio
Externí odkaz:
https://doaj.org/article/7b36e4f4e47e4e7ea1556bc362fd401d
Autor:
Marc A J Morgan, Pari S S Muller, Arne Mould, Stephen A Newland, Jennifer Nichols, Elizabeth J Robertson, Anne Cooke, Elizabeth K Bikoff
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56738 (2013)
The spontaneous destruction of insulin producing pancreatic beta cells in non-obese diabetic (NOD) mice provides a valuable model of type 1 diabetes. As in humans, disease susceptibility is controlled by the classical MHC class II genes that guide CD
Externí odkaz:
https://doaj.org/article/7eebef782171470eb7208f3e17de928d
Autor:
Ivan M. Roitt, Anne Cooke
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 82, Pp 105-109 (1987)
1. Autoimmunity in deisease is driven by autoantigen; 2. Cell surface molecules may stimulate autoreactive T-helpers if call II MHC is expressed; special factors may predispose to the ease of class II induction; 3. Soluble autoantigens may be focusse
Externí odkaz:
https://doaj.org/article/9602c41412f248a6b348bc479312a6ad
Publikováno v:
Psychosis. :1-13
Publikováno v:
Psychosis. :1-11
Publikováno v:
Journal of Public Mental Health, 2016, Vol. 15, Issue 2, pp. 103-114.
Externí odkaz:
http://www.emeraldinsight.com/doi/10.1108/JPMH-01-2016-0006