Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Anne Chester"'
Autor:
April D Lake, Kevin Holsapple, Tanya McDonnell, Joseph C Arezzo, Ricardo Ramirez, Lindsay Gamelin, Mei Yu, Dylan Glatt, Ryan Dick, Xiaodong Xie, Regina Choy, Guofeng Cheng, Chin H Tay, Anne Chester, Darryl Kato, Leigh Ann Burns-Naas
Publikováno v:
Toxicological Sciences. 186:298-308
The nonclinical safety profile of GS-8873, a hepatitis B virus RNA transcript inhibitor was evaluated in rat and monkey 13-week toxicity studies with 8-week recovery phases. Vehicle or GS-8873 was dosed orally for 13 weeks at 2, 6, 20, and 60 mg/kg/d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72019e0b0b0a251453a80ddac1615d2b
https://doi.org/10.1093/toxsci/kfac009
https://doi.org/10.1093/toxsci/kfac009
Autor:
Anne Chester, Curtis Colleton, Michael J. Graziano, David O. Clarke, Peter Heining, David W. Brewster, Andrew J. Olaharski
Publikováno v:
Toxicologic Pathology. 44:458-466
The use of minipigs in preclinical safety testing of pharmaceuticals is considered an alternative to the more traditional dog and nonhuman primate (NHP) nonrodent species. Substantial evidence exists to suggest that the anatomy, physiology, and bioch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::482e64815a4d650e7fbb82269ac5c458
https://doi.org/10.1177/0192623315617562
https://doi.org/10.1177/0192623315617562
Publikováno v:
Dermatotoxicology, Seventh Edition ISBN: 9780849397738
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69dbd2333915884acd48eab2aa219e08
https://doi.org/10.1201/9780203426272.ch35
https://doi.org/10.1201/9780203426272.ch35
Publikováno v:
Drugs and the Pharmaceutical Sciences ISBN: 9780824708696
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7f079a91435c56560120f76d939b4f6
https://doi.org/10.1201/9780203910337.ch41
https://doi.org/10.1201/9780203910337.ch41
Publikováno v:
Drugs and the Pharmaceutical Sciences ISBN: 9780824708696
Modified-Release Drug Delivery Technology
Modified-Release Drug Delivery Technology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf40229386a1e7781c3c144727856fea
https://doi.org/10.1201/9780203910337.ch40
https://doi.org/10.1201/9780203910337.ch40
Publikováno v:
Drugs and the Pharmaceutical Sciences ISBN: 9780824708696
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af2dad98756b4cf17620ec8ed1fd3b8c
https://doi.org/10.1201/9780203910337.ch55
https://doi.org/10.1201/9780203910337.ch55
Publikováno v:
The Medical journal of Australia. 142(12)
The plasma pharmacokinetics of warfarin were studied in a patient who took an overdose of warfarin (2000 mg by mouth), together with 25 X 10(4) units of heparin administered subcutaneously. The plasma warfarin level fell rapidly (half-life, 21.7 h),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca45a03bf4f70c18fc83662bec182a72
https://pubmed.ncbi.nlm.nih.gov/4000042
https://pubmed.ncbi.nlm.nih.gov/4000042