Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Anne Charlet"'
Autor:
Silvia Waldeck, Michael Rassner, Philip Keye, Marie Follo, Dieter Herchenbach, Cornelia Endres, Anne Charlet, Geoffroy Andrieux, Ulrich Salzer, Melanie Boerries, Justus Duyster, Nikolas vonBubnoff
Publikováno v:
Molecular Oncology, Vol 14, Iss 4, Pp 779-794 (2020)
FLT3‐ITD tyrosine kinase inhibitors (TKI) show limited clinical activity in acute myeloid leukemia (AML) due to emerging resistance. TKI resistance is mediated by secondary FLT3‐ITD mutations only in a minority of cases. We hypothesize that the c
Externí odkaz:
https://doaj.org/article/bd63d97f309d4829be7c3c0875737bfc
Autor:
Philip Keye, Anne Charlet, Michael Reth, Kathrin Kläsener, Max Kappenstein, Cornelia Endres, Teresa Poggio, Nikolas von Bubnoff, Anna Lena Illert, Jana Sänger, Stefanie Kreutmair, Cornelius Miething, Christoph Rummelt, Justus Duyster, Sivahari P. Gorantla
Publikováno v:
Leukemia. 36:701-711
FLT3-ITD is the most predominant mutation in AML being expressed in about one-third of AML patients and is associated with a poor prognosis. Efforts to better understand FLT3-ITD downstream signaling to possibly improve therapy response are needed. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fb8aa8e0d51349749e9a105ed9eb4bc
https://doi.org/10.1038/s41375-021-01462-4
https://doi.org/10.1038/s41375-021-01462-4
Autor:
Lisa I. Born, Theresa Andree, Svenja Frank, Judith Hübner, Sandra Link, Marion Langheine, Anne Charlet, Jennifer S. Esser, Ralph Brehm, Martin Moser
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 17; Pages: 10075
The eukaryotic initiation factor 4E binding protein (4E-BP) family is involved in translational control of cell proliferation and pro-angiogenic factors. The zebrafish eukaryotic initiation factor 4E binding protein 3 like (eif4ebp3l) is a member of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b0e0191a1a5970357c84e9def1d4f71
Autor:
Christoph Rummelt, Justus Duyster, Florian H Heidel, Anne Charlet, Konstanze Döhner, Thomas Fischer, Nikolas von Bubnoff, Sivahari P. Gorantla, Cornelia Endres, Manja Meggendorfer, Torsten Haferlach
Publikováno v:
Leukemia. 35:2017-2029
An important limitation of FLT3 tyrosine kinase inhibitors (TKIs) in FLT3-ITD positive AML is the development of resistance. To better understand resistance to FLT3 inhibition, we examined FLT3-ITD positive cell lines which had acquired resistance to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6bf3121d45f4d063ada7449cf0ae05
https://doi.org/10.1038/s41375-020-01077-1
https://doi.org/10.1038/s41375-020-01077-1
Autor:
Melanie Boerries, Geoffroy Andrieux, Ulrich Salzer, Michael Rassner, Silvia Waldeck, Nikolas von Bubnoff, Anne Charlet, Dieter Herchenbach, Justus Duyster, Cornelia Endres, Philip Keye, Marie Follo
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 14, Iss 4, Pp 779-794 (2020)
Molecular Oncology, Vol 14, Iss 4, Pp 779-794 (2020)
FLT3‐ITD tyrosine kinase inhibitors (TKI) show limited clinical activity in acute myeloid leukemia (AML) due to emerging resistance. TKI resistance is mediated by secondary FLT3‐ITD mutations only in a minority of cases. We hypothesize that the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e34a480c7832b6726c4b8e70e3183f09
https://doi.org/10.1002/1878-0261.12640
https://doi.org/10.1002/1878-0261.12640
Autor:
Anne, Charlet, Max, Kappenstein, Philip, Keye, Kathrin, Kläsener, Cornelia, Endres, Teresa, Poggio, Sivahari P, Gorantla, Stefanie, Kreutmair, Jana, Sänger, Anna L, Illert, Cornelius, Miething, Michael, Reth, Justus, Duyster, Christoph, Rummelt, Nikolas, von Bubnoff
Publikováno v:
Leukemia. 36(3)
FLT3-ITD is the most predominant mutation in AML being expressed in about one-third of AML patients and is associated with a poor prognosis. Efforts to better understand FLT3-ITD downstream signaling to possibly improve therapy response are needed. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc07ab8d92a1337b286a0127b5c886f7
https://pubmed.ncbi.nlm.nih.gov/34750506
https://pubmed.ncbi.nlm.nih.gov/34750506
Autor:
Anne Charlet, Jeanette Andersen, Helga Ovens, Annemarie Sluijmers, Kirsi Myllys, Alain Cornet
Publikováno v:
Poster presentations.
Background Patients involvement has massively changed over the years. From patients as ‘objects’ of care, we have moved to patient centric approaches and are now embarking at full speed in the era of patients as partners. To better meet this evol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a03500c0d0cf7fd81c90f9483bba0684
https://doi.org/10.1136/lupus-2020-eurolupus.185
https://doi.org/10.1136/lupus-2020-eurolupus.185
Autor:
Annemarie Sluijmers, Alain Cornet, Anne Charlet, Kirsi Myllys, Jeanette Andersen, Helga Ovens
Publikováno v:
Poster presentations.
Background Up to 80% of all Lupus patients experience fatigue and most of them report this as the most severe symptom. One of the major causes of morbidity in SLE patients is chronic, debilitating fatigue, decreasing quality of life, increasing risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de769c9c8808ab19fc4ae6da6fb74966
https://doi.org/10.1136/lupus-2020-eurolupus.154
https://doi.org/10.1136/lupus-2020-eurolupus.154
Autor:
Kirsi Myllys, Marisa Costa, Annemarie Sluijmers, Jeanette Andersen, Alain Cornet, Anne Charlet, Elfried Wijsma
Publikováno v:
Invited talks.
Background Lupus patient’s expectations are no different than everyone else’s: ‘A better life’. But achieving it requires different steps because it entails (1) A prompt diagnosis, (2) Access to effective treatment with low side-effects, (3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09e72de00d1c04f5b6e061d65a280563
https://doi.org/10.1136/lupus-2020-eurolupus.7
https://doi.org/10.1136/lupus-2020-eurolupus.7
Autor:
Meike Deckler, Cam Patterson, Anne Charlet, Jennifer S. Esser, Rahel Elisabeth Steiner, Hannah Schmitt, Qian Zhou, Bianca Engert, Christoph Bode, Martin Moser, Sandra Link
Publikováno v:
The FEBS Journal. 285:1419-1436
The bone morphogenetic protein (BMP) signaling pathway plays a central role during vasculature development. Mutations or dysregulation of the BMP pathway members have been linked to arteriovenous malformations. In the present study, we investigated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aec88ded768619925e1c0ab9eb5fe49a
https://doi.org/10.1111/febs.14414
https://doi.org/10.1111/febs.14414