Efficient treatment of a metastatic melanoma patient with a combination of BRAF and MEK inhibitors based on circulating tumor DNA analysis: a case report

Autor: Gaelle Quéreux, Guillaume Herbreteau, Anne-Chantal Knol, Audrey Vallée, Amir Khammari, Sandrine Théoleyre, Mélanie Saint-Jean, Brigitte Dréno, Marc G. Denis

Publikováno v: BMC Research Notes, Vol 10, Iss 1, Pp 1-4 (2017)

Abstract Background Fixed tissues are the standard samples used in routine practice for molecular testing. But sometimes tissues are lacking or difficult to obtain. In these cases, circulating tumor DNA released from tumor cells can be used as an alt

Externí odkaz: https://doaj.org/article/039b62cdd15444f183bc1dafe7914d54

Supplemental figure legends from Emergence of High-Avidity Melan-A–Specific Clonotypes as a Reflection of Anti–PD-1 Clinical Efficacy

Autor: Nathalie Labarriere, Brigitte Dreno, Francois Lang, Nadine Gervois, Amir Khammari, Anne-Chantal Knol, Tiphaine Parrot, Emilie Varey, Virginie Vignard, Sylvain Simon

Legends of supplemental figures S1, S2, S3 and S4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b2c3ca029bf6cebf47320e7e8c51ed
https://doi.org/10.1158/0008-5472.22416515.v1

Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes in Advanced Melanoma Patients

Autor: Mélanie Saint-Jean, Anne-Chantal Knol, Christelle Volteau, Gaëlle Quéreux, Lucie Peuvrel, Anabelle Brocard, Marie-Christine Pandolfino, Soraya Saiagh, Jean-Michel Nguyen, Christophe Bedane, Nicole Basset-Seguin, Amir Khammari, Brigitte Dréno

Publikováno v: Journal of Immunology Research, Vol 2018 (2018)

Immunotherapy for melanoma includes adoptive cell therapy with autologous tumor-infiltrating lymphocytes (TILs). This monocenter retrospective study was undertaken to evaluate the efficacy and safety of this treatment of patients with advanced melano

Externí odkaz: https://doaj.org/article/36f49e1a78814611842a3f33a76fcd99

Adoptive TIL Transfer in the Adjuvant Setting for Melanoma: Long-Term Patient Survival

Autor: Amir Khammari, Anne-Chantal Knol, Jean-Michel Nguyen, Céline Bossard, Marc-Guillaume Denis, Marie-Christine Pandolfino, Gaëlle Quéreux, Sylvain Bercegeay, Brigitte Dréno

Publikováno v: Journal of Immunology Research, Vol 2014 (2014)

Two first analyses of our clinical trial on TIL as adjuvant therapy for melanoma were published in 2002 and 2007. We present here an update of the clinical results after a 17-year median followup. In this trial, disease-free patients were randomly as

Externí odkaz: https://doaj.org/article/68c98e8d0f654019869d06be4d6f543c

Circulating Tumor DNA Early Kinetics Predict Response of Metastatic Melanoma to Anti-PD1 Immunotherapy: Validation Study

Autor: Audrey Vallée, Amir Khammari, Brigitte Dréno, Anne-Chantal Knol, Guillaume Herbreteau, Emilie Varey, Marc G. Denis, Sandrine Théoleyre, Gaëlle Quéreux

Publikováno v: Cancers
Cancers, MDPI, 2021, 13 (8), pp.1826. ⟨10.3390/cancers13081826⟩
Cancers, Vol 13, Iss 1826, p 1826 (2021)
Cancers, 2021, 13 (8), pp.1826. ⟨10.3390/cancers13081826⟩
Volume 13
Issue 8

The ability of early (first weeks of treatment) ctDNA kinetics to identify primary resistance to anti-PD1 immunotherapies was evaluated with a validation cohort of 49 patients treated with anti‑PD1 for metastatic BRAF or NRAS-mutated melanoma, alon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c4698d3fe9ebfedb9de2d1db826dac
https://pubmed.ncbi.nlm.nih.gov/33920470