Zobrazeno 1 - 10
of 425
pro vyhledávání: '"Anne Catrin Uhlemann"'
Autor:
Krittikorn Kümpornsin, Theerarat Kochakarn, Tomas Yeo, John Okombo, Madeline R. Luth, Johanna Hoshizaki, Mukul Rawat, Richard D. Pearson, Kyra A. Schindler, Sachel Mok, Heekuk Park, Anne-Catrin Uhlemann, Gouranga P. Jana, Bikash C. Maity, Benoît Laleu, Elodie Chenu, James Duffy, Sonia Moliner Cubel, Virginia Franco, Maria G. Gomez-Lorenzo, Francisco Javier Gamo, Elizabeth A. Winzeler, David A. Fidock, Thanat Chookajorn, Marcus C. S. Lee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract In vitro evolution of drug resistance is a powerful approach for identifying antimalarial targets, however, key obstacles to eliciting resistance are the parasite inoculum size and mutation rate. Here we sought to increase parasite genetic d
Externí odkaz:
https://doaj.org/article/cd0bb7acaa454eeba503bf34e9f1ecc8
Autor:
Mehrose Ahmad, Hannah Prensky, Jacqueline Balestrieri, Shahd ElNaggar, Angela Gomez-Simmonds, Anne-Catrin Uhlemann, Beth Traxler, Abhyudai Singh, Allison J. Lopatkin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Conjugative plasmids drive genetic diversity and evolution in microbial populations. Despite their prevalence, plasmids can impose long-term fitness costs on their hosts, altering population structure, growth dynamics, and evolutionary outco
Externí odkaz:
https://doaj.org/article/7b1dfcdeff5c4b6baee8fcdf0074f547
Autor:
Marilena Aquino de Muro, Igor Shuryak, Anne‐Catrin Uhlemann, Alice Tillman, Dwayne Seeram, Joseph Zakaria, David Welch, Steven M. Erde, David J. Brenner
Publikováno v:
MicrobiologyOpen, Vol 12, Iss 2, Pp n/a-n/a (2023)
Abstract The dental clinic air microbiome incorporates microbes from the oral cavity and upper respiratory tract (URT). This study aimed to establish a reliable methodology for air sampling in a dental clinic setting and quantify the abundance of cul
Externí odkaz:
https://doaj.org/article/fc1284169f0246248dc45863c5ca58f6
Autor:
Amelia St. John, Andrew I. Perault, Sabrina I. Giacometti, Alexis G. Sommerfield, Ashley L. DuMont, Keenan A. Lacey, Xuhui Zheng, Julia Sproch, Chris Petzold, Kristen Dancel-Manning, Sandra Gonzalez, Medini Annavajhala, Colleen Beckford, Nathalie Zeitouni, Feng-Xia Liang, Harm van Bakel, Bo Shopsin, Anne-Catrin Uhlemann, Alejandro Pironti, Victor J. Torres
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Nosocomial infections caused by multidrug-resistant (MDR) Enterobacter cloacae complex (ECC) pathogens are on the rise. However, the virulence strategies employed by these pathogens remain elusive. Here, we study the interaction of ECC clini
Externí odkaz:
https://doaj.org/article/d3aff886dd104f129b126519af1d6e50
Autor:
Lawrence J. Purpura, Joseph Alukal, Alexander M. Chong, Lihong Liu, Anyelina Cantos, Jayesh Shah, Nicola Medrano, Jennifer Y. Chang, Moriya Tsuji, Hiroshi Mohri, Anne Catrin Uhlemann, David Ho, Michael T. Yin
Publikováno v:
Emerging Infectious Diseases, Vol 28, Iss 1, Pp 196-200 (2022)
We report severe acute respiratory syndrome coronavirus 2 in semen by using quantitative reverse transcription PCR during the late convalescent phase. Virus was associated with adequate humoral and cell-mediated responses, suggesting possible seeding
Externí odkaz:
https://doaj.org/article/7d936e2e06104d43a8ab45e9b372f80c
Autor:
Medini K. Annavajhala, Nicole E. Kelly, Wenjing Geng, Samantha A. Ferguson, Marla J. Giddins, Emily C. Grohs, Alexandra Hill-Ricciuti, Daniel A. Green, Lisa Saiman, Anne-Catrin Uhlemann
Publikováno v:
mSphere, Vol 7, Iss 6 (2022)
ABSTRACT Methicillin-susceptible Staphylococcus aureus (MSSA) is a more prevalent neonatal intensive care unit (NICU) pathogen than methicillin-resistant S. aureus (MRSA). However, the introduction and spread of MSSA, the role of systematic decoloniz
Externí odkaz:
https://doaj.org/article/6fd58f027b994e0bbaf587b6c49035a9
Autor:
Hector Cordero, Rodney G. King, Pranay Dogra, Chloe Dufeu, Sarah B. See, Alexander M. Chong, Anne-Catrin Uhlemann, Siu-Hong Ho, David M. Kalfa, Emile A. Bacha, John F. Kearney, Emmanuel Zorn
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The thymus is known as the organ of T lymphocyte development. Here authors show that terminal B cell differentiation also takes place in the thymus of human neonates, leading to antibody production against commensal and pathogenic bacteria.
Externí odkaz:
https://doaj.org/article/e3974adc67504d398d0283ef6c71a113
Autor:
Angela Gomez-Simmonds, Medini K. Annavajhala, Maria Patricia Nunez, Nenad Macesic, Heekuk Park, Anne-Catrin Uhlemann
Publikováno v:
mSphere, Vol 7, Iss 5 (2022)
ABSTRACT Clostridioides difficile infection (CDI) has a higher incidence in solid organ transplant recipients than other hospitalized patients and can lead to poor outcomes. Perturbations to the intestinal microbiome are common in patients undergoing
Externí odkaz:
https://doaj.org/article/6e7e38184c1b440498f423f00d48da2b
Autor:
Lihong Liu, Kathrine Meyers, Lawrence J. Purpura, Nadia Nguyen, Hiroshi Mohri, Jennifer Y. Chang, Medini K. Annavajhala, Leo Lopez, III, Sang Won Lee, Jayesh Shah, Benjamin Lane, Anyelina Cantos, Sade A. Tukuru, Yicheng Guo, Kenra Ford, Yueh-Ting Chiu, Zizhang Sheng, Tenzin Choesang, Delivette Castor, Maple Wang, Christina Pili, Michael N. Van Hoy, Andrew Wallach, Jamie Horton, Zhiqiang Chen, Susan Rosenthal, Son McLaren, Baowei Jiang, Frank Wang, Helen H. Lu, Anne-Catrin Uhlemann, David D. Ho, Michael T. Yin
Publikováno v:
Journal of Clinical Virology Plus, Vol 2, Iss 3, Pp 100080- (2022)
Background: SARS-CoV-2 antigen-based tests are well-calibrated to infectiousness and have a critical role to play in the COVID-19 public health response. We report the development and performance of a unique lateral flow immunoassay (LFA). Methods: C
Externí odkaz:
https://doaj.org/article/1e49f45485da4fa6bdea22f19f9e718f
Autor:
Kira L. Tomlinson, Tania Wong Fok Lung, Felix Dach, Medini K. Annavajhala, Stanislaw J. Gabryszewski, Ryan A. Groves, Marija Drikic, Nancy J. Francoeur, Shwetha H. Sridhar, Melissa L. Smith, Sara Khanal, Clemente J. Britto, Robert Sebra, Ian Lewis, Anne-Catrin Uhlemann, Barbara C. Kahl, Alice S. Prince, Sebastián A. Riquelme
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The authors show that the pathogen Staphylococcus aureus induces a distinct airway immunometabolic response, dominated by release of itaconate. This metabolite, in turn, potentiates extracellular polysaccharide synthesis and biofilm formation in S. a
Externí odkaz:
https://doaj.org/article/31b0833e7deb4acab5af4327ac64931d