Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Anne C. Vetica"'
Autor:
David H. Perlmutter, Cliff J. Luke, Olivia S. Long, Anne C. Vetica, Sangeeta R. Bhatia, Gary A. Silverman, Stephen C. Pak
Publikováno v:
Pediatric Research. 65:10-18
As an experimental system, Caenorhabditis elegans, offers a unique opportunity to interrogate in vivo the genetic and molecular functions of human disease-related genes. For example, C. elegans has provided crucial insights into fundamental biologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30128bab4f9ae857abd30e70952c3287
https://doi.org/10.1203/pdr.0b013e31819009b0
https://doi.org/10.1203/pdr.0b013e31819009b0
Autor:
Stephen C. Pak, Robert Barstead, Gary Moulder, Terra L. Naviglia, Yuko S. Askew, Olivia S. Long, Anne C. Vetica, Shila M. Nobar, David J. Askew, Simon C. Watkins, Donna B. Stolz, Gary A. Silverman, Cliff J. Luke, Dieter Brömme
Publikováno v:
Cell. 130(6):1108-1119
Summary Extracellular serpins such as antithrombin and α1-antitrypsin are the quintessential regulators of proteolytic pathways. In contrast, the biological functions of the intracellular serpins remain obscure. We now report that the C. elegans int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fbe7b2fd7b21ed3053156bf05318ba6
Autor:
Yan Wang, Mark T. Miedel, Gary A. Silverman, David H. Perlmutter, Simon C. Watkins, Linda P. O’Reilly, Joshua A. Benson, Stephen C. Pak, Stephan Züchner, Jie Li, Joon Hyeok Kwak, Sager J. Gosai, Olivia S. Long, Anne C. Vetica, Donna B. Stolz, Cliff J. Luke
Publikováno v:
Human molecular genetics. 23(19)
The accumulation of serpin oligomers and polymers within the endoplasmic reticulum (ER) causes cellular injury in patients with the classical form α1-antitrypsin deficiency (ATD). To better understand the cellular and molecular genetic aspects of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5f7244781cfea148dded5410106f88e
https://pubmed.ncbi.nlm.nih.gov/24838286
https://pubmed.ncbi.nlm.nih.gov/24838286