Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Anne C. Cotleur"'
Autor:
Kaira A. Church, Derek Rodriguez, Andrew S. Mendiola, Difernando Vanegas, Irene L. Gutierrez, Ian Tamayo, Abdul Amadu, Priscila Velazquez, Sandra M. Cardona, Stefka Gyoneva, Anne C. Cotleur, Richard M. Ransohoff, Tejbeer Kaur, Astrid E. Cardona
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Diabetic retinopathy, a microvascular disease characterized by irreparable vascular damage, neurodegeneration and neuroinflammation, is a leading complication of diabetes mellitus. There is no cure for DR, and medical interventions marginally slow th
Externí odkaz:
https://doaj.org/article/2061e61566104f23b60844866d5b9d5b
Autor:
Noah Saederup, Astrid E Cardona, Kelsey Croft, Makiko Mizutani, Anne C Cotleur, Chia-Lin Tsou, Richard M Ransohoff, Israel F Charo
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176931 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0013693.].
Externí odkaz:
https://doaj.org/article/9f838fc6f71247af8525f2a988b1ce8e
Autor:
Noah Saederup, Astrid E Cardona, Kelsey Croft, Makiko Mizutani, Anne C Cotleur, Chia-Lin Tsou, Richard M Ransohoff, Israel F Charo
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13693 (2010)
Monocyte subpopulations distinguished by differential expression of chemokine receptors CCR2 and CX3CR1 are difficult to track in vivo, partly due to lack of CCR2 reagents.We created CCR2-red fluorescent protein (RFP) knock-in mice and crossed them w
Externí odkaz:
https://doaj.org/article/04d8c76e2cab47ecab74c9d9ba98f4f2
Publikováno v:
Oligodendrocytes ISBN: 9781493990702
Remyelination is the regenerative process whereby myelin sheaths are restored around axons following nervous system injury, allowing reinstatement of electrical impulse conduction, trophic/metabolic support, and axon health. Failure of remyelination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9286a89b9b8607a9c37bd8ca9ec410a
https://doi.org/10.1007/978-1-4939-9072-6_2
https://doi.org/10.1007/978-1-4939-9072-6_2
Autor:
Patrick Cullen, Taylor L. Reynolds, Anne C. Cotleur, David Gosselin, Michael Peterson, Richard M. Ransohoff, Baohong Zhang, Raghavendra Hosur, Chris Roberts, Ravi Challa, Linda C. Burkly, Christopher K. Glass, Norm Allaire, Kelly Miao, Stefka Gyoneva, Zhengyu Ouyang
Publikováno v:
Life Science Alliance
Life science alliance, vol 2, iss 6
Life science alliance, vol 2, iss 6
Gyoneva et al use RNA-seq to show that Cx3cr1-deficient microglia in young mice display a gene expression profile similar to microglia in aged mice, suggesting premature microglial aging.
CX3CR1, one of the highest expressed genes in microglia i
CX3CR1, one of the highest expressed genes in microglia i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30df5ee2e6902a23d79a59e2aec2356a
https://doi.org/10.26508/lsa.201900453
https://doi.org/10.26508/lsa.201900453
Autor:
Guixiang Xu, Gareth R. Howell, Crystal M. Miller, Richard M. Ransohoff, Taylor R. Jay, James B. Leverenz, Susan M. Staugaitis, J. Colleen Karlo, Oleg Butovsky, Paul J. Cheng, Daniel Margevicius, Gary E. Landreth, Leah C. Graham, Bruce T. Lamb, Gregory L. Sousa, Shane M. Bemiller, Anne C. Cotleur, Sanjay W. Pimplikar, Lynn M. Bekris, Margaret L. Broihier
Publikováno v:
The Journal of Experimental Medicine
Jay and colleagues show that TREM2 deficiency reduces the number of macrophages infiltrating the brain and is protective against disease pathogenesis in mouse models of Alzheimer’s disease.
Variants in triggering receptor expressed on myeloid
Variants in triggering receptor expressed on myeloid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a9ba6ad83e3cd254be8ebb6ade44e8e
https://doi.org/10.1084/jem.20142322
https://doi.org/10.1084/jem.20142322
Autor:
Yasuteru Sano, Richard M. Ransohoff, Thomas J. Kryzer, Fumitaka Shimizu, Gregory P. Owens, Vanda A. Lennon, Yukio Takeshita, Kristin Schaller, Anne C. Cotleur, Debra Kellner, Jeffrey Bennett, Birgit Obermeier, Takashi Kanda
Publikováno v:
Science Translational Medicine. 9
Neuromyelitis optica (NMO) is an inflammatory disorder mediated by antibodies to aquaporin-4 (AQP4) with prominent blood-brain barrier (BBB) breakdown in the acute phase of the disease. Anti-AQP4 antibodies are produced mainly in the periphery, yet t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6985f037720d705e892a77b324ee8d18
https://doi.org/10.1126/scitranslmed.aai9111
https://doi.org/10.1126/scitranslmed.aai9111
Autor:
Birgit Obermeier, Yasuteru Sano, Erin Yamamoto, Fumitaka Shimizu, Thomas J. Kryzer, Vanda A. Lennon, Yukio Takeshita, Anne C. Cotleur, Simona Federica Spampinato, Takashi Kanda, Richard M. Ransohoff
Publikováno v:
Neurology® Neuroimmunology & Neuroinflammation
Objective:To address the hypothesis that physiologic interactions between astrocytes and endothelial cells (EC) at the blood–brain barrier (BBB) are afflicted by pathogenic inflammatory signaling when astrocytes are exposed to aquaporin-4 (AQP4) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fa9ac4aa9becdd4545cbf84baddbd15
http://hdl.handle.net/2318/1841023
http://hdl.handle.net/2318/1841023
Autor:
Nobuhiko Ohno, Pauline M. Wu, Ryo Yamasaki, Lindsey Uehlein, Oleg Butovsky, Israel F. Charo, Weiwei Hu, Jessica Lin, Min Zhu, Jinyu Gu, LiPing Liu, Howard L. Weiner, Debra Dixon, Grahame J. Kidd, Nathan Sun, Jar Chi Lee, Anne C. Cotleur, Ron Cialic, Musab M. Zorlu, Anna Rietsch, Haiyan Lu, Richard M. Ransohoff, Sarah E. Taylor, Crina M. Floruta, Camille Doykan
Publikováno v:
The Journal of Experimental Medicine
Phagocytic monocyte-derived macrophages associate with the nodes of Ranvier and initiate demyelination while microglia clear debris and display a suppressed metabolic gene signature in EAE.
In the human disorder multiple sclerosis (MS) and in th
In the human disorder multiple sclerosis (MS) and in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be8ba7134762cdf4cfb49614c02efe20
https://doi.org/10.1084/jem.20132477
https://doi.org/10.1084/jem.20132477
Autor:
Anne C. Cotleur, Lauren Koffman, Joao Gomes, Gábor Tóth, J. Javier Provencio, Khaled Asi, Magdy Selim, M. Shazam Hussain
Publikováno v:
Neurocritical Care. 21:285-293
Iron-mediated oxidative damage has been implicated in the genesis of cerebral vasospasm in animal models of SAH. We sought to explore the relationship between levels of non-protein bound iron in cerebrospinal fluid and the development of brain injury
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e02ed6a60d707c0fee04078df3ba475e
https://doi.org/10.1007/s12028-014-9977-8
https://doi.org/10.1007/s12028-014-9977-8