Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Anne C. Bachg"'
Autor:
Esther van den Bos, Stefan Walbaum, Benjamin Ambrosy, Giulio Innamorati, Thomas M. Wilkie, Peter J. Hanley, Markus Horsthemke, Nina Wettschureck, Anne C. Bachg
Publikováno v:
J Biol Chem
G protein–coupled receptor signaling is required for the navigation of immune cells along chemoattractant gradients. However, chemoattractant receptors may couple to more than one type of heterotrimeric G protein, each of which consists of a Gα, G
Autor:
Markus Horsthemke, Peter J. Hanley, Anne C. Bachg, Stefan Walbaum, Attila Mócsai, Benjamin Ambrosy, Jeanette H. W. Leusen, Paula Schütz
Publikováno v:
The Journal of Biological Chemistry
A long-standing hypothesis is that complement receptors (CRs), especially CR3, mediate sinking phagocytosis, but evidence is lacking. Alternatively, CRs have been reported to induce membrane ruffles or phagocytic cups, akin to those induced by Fcγ r
Publikováno v:
Journal of Visualized Experiments.
Chemotaxis is receptor-mediated guidance of cells along a chemical gradient, whereas chemokinesis is the stimulation of random cell motility by a chemical. Chemokinesis and chemotaxis are fundamental for the mobilization and deployment of immune cell
Autor:
Sven Moyzio, Markus Horsthemke, Michael Sixt, Sandra A. Hemkemeyer, Martin Bähler, Roland Wedlich-Söldner, Peter J. Hanley, Sebastian Tacke, Anne C. Bachg, Barbara Müther, Katharina Groll
Publikováno v:
Journal of Biological Chemistry. 292:7258-7273
Macrophage filopodia, finger-like membrane protrusions, were first implicated in phagocytosis more than 100 years ago, but little is still known about the involvement of these actin-dependent structures in particle clearance. Using spinning disk conf
Autor:
Wolfgang A. Linke, Markus Horsthemke, Ursula Ravens, Frank U. Müller, Matthias D. Seidl, Monika Stoll, Pim R.R. van Gorp, Peter J. Hanley, Boris V. Skryabin, Thomas Zobel, Andreas Unger, Antoine A.F. de Vries, Ulrike Honnert, Anne C. Bachg, Martin Bähler, Lauryl M.J. Nutter, Sven Bogdan
Whereas myosin 18B (Myo18B) is known to be a critical sarcomeric protein, the function of myosin 18A (Myo18A) is unclear, although it has been implicated in cell motility and Golgi shape. Here, we show that homozygous deletion (homozygous tm1a, tm1b,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f1d2194887850de915051658f22e31
https://hdl.handle.net/1887/122160
https://hdl.handle.net/1887/122160
Autor:
Martin Bähler, Tim Klasen, Peter J. Hanley, Hyun-Woo Jeong, Emma F. Woodham, Sandra Bachg, Boris V. Skryabin, Nina Nagelmann, Cornelius Faber, Richard Stange, Anne C. Bachg, Laura M. Machesky, Ralf H. Adams, Markus Horsthemke
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-22 (2019)
We investigated the physiological functions of Myo10 (myosin X) using Myo10 reporter knockout (Myo10tm2) mice. Full-length (motorized) Myo10 protein was deleted, but the brain-specific headless (Hdl) isoform (Hdl-Myo10) was still expressed in homozyg
Publikováno v:
J Vis Exp
Phagocytosis plays a key role in host defense, as well as in tissue development and maintenance, and involves rapid, receptor-mediated rearrangements of the actin cytoskeleton to capture, envelop and engulf large particles. Although phagocytic recept
Autor:
Anne C, Bachg, Markus, Horsthemke, Boris V, Skryabin, Tim, Klasen, Nina, Nagelmann, Cornelius, Faber, Emma, Woodham, Laura M, Machesky, Sandra, Bachg, Richard, Stange, Hyun-Woo, Jeong, Ralf H, Adams, Martin, Bähler, Peter J, Hanley
Publikováno v:
Scientific Reports
We investigated the physiological functions of Myo10 (myosin X) using Myo10 reporter knockout (Myo10tm2) mice. Full-length (motorized) Myo10 protein was deleted, but the brain-specific headless (Hdl) isoform (Hdl-Myo10) was still expressed in homozyg
Autor:
Sandra Bachg, Markus Horsthemke, Boris V. Skryabin, Emma F. Woodham, Tim Klasen, Martin Bähler, Richard Stange, Laura M. Machesky, Ralf H. Adams, Peter J. Hanley, Anne C. Bachg, Nina Nagelmann, Hyun-Woo Jeong, Cornelius Faber
Publikováno v:
The FASEB Journal. 32
Autor:
Kay Grobe, Martin Bähler, Cord Brakebusch, Albrecht Schwab, Volker Königs, Richard T. Jennings, Ulla G. Knaus, Thomas Vogl, Anne C. Bachg, Yan Xu, Markus Horsthemke, Peter J. Hanley
Publikováno v:
The Journal of biological chemistry. 289(44)
RhoA is thought to be essential for coordination of the membrane protrusions and retractions required for immune cell motility and directed migration. Whether the subfamily of Rho (Ras homolog) GTPases (RhoA, RhoB, and RhoC) is actually required for