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Altered Cholinergic Innervation in De Novo Parkinson's Disease with and Without Cognitive Impairment
Autor:
Sygrid van der Zee, Prabesh Kanel, Marleen J.J. Gerritsen, Jeffrey M. Boertien, Anne C. Slomp, Martijn L.T.M. Müller, Nicolaas I. Bohnen, Jacoba M. Spikman, Teus van Laar
Publikováno v:
Movement Disorders, 37(4), 713-723. Wiley
BACKGROUND: Altered cholinergic innervation plays a putative role in cognitive impairment in Parkinson's disease (PD) at least in advanced stages. Identification of the relationship between cognitive impairment and cholinergic innervation early in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd20389f3389c62ccb3e70dc9e9f2de0
https://hdl.handle.net/11370/5ce26836-b1ba-448d-8cf1-3f4d2a06152d
https://hdl.handle.net/11370/5ce26836-b1ba-448d-8cf1-3f4d2a06152d
Autor:
Jeffrey M Boertien, Muhammad Nazmuddin, Justyna Kłos, Anne C Slomp, Sygrid van der Zee, Ronald JH Borra, Teus van Laar
Recently, the α-Synuclein Origin and Connectome (SOC) model of Parkinson’s disease (PD) has been proposed, which predicts a more malignant clinical subtype and symmetrical neurodegeneration in body-first compared to brain-first PD.Here, motor symp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65569f86fa8866148efad3ebffbe6c93
https://doi.org/10.1101/2022.12.23.22283910
https://doi.org/10.1101/2022.12.23.22283910
