Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Anne Bonnaud"'
Autor:
Céline Legros, Clémence Dupré, Chantal Brasseur, Anne Bonnaud, Olivier Bruno, Damien Valour, Preety Shabajee, Adeline Giganti, Olivier Nosjean, Terrence P. Kenakin, Jean A. Boutin
Publikováno v:
Pharmacology Research & Perspectives, Vol 8, Iss 1, Pp n/a-n/a (2020)
Abstract Melatonin is a neurohormone that translates the circadian rhythm to the peripheral organs through a series of binding sites identified as G protein‐coupled receptors MT1 and MT2. Due to minute amounts of receptor proteins in target organs,
Externí odkaz:
https://doaj.org/article/08643ceb060e4077bb6c6bb5129fe136
Autor:
Jean-Philippe Stephan, Philippe Delagrange, Valérie Audinot, Preety Shabajee-Alibay, Saïd Yous, Benoît Malpaux, Jérôme Leprince, Anne Bonnaud, Jean A. Boutin, Céline Legros
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 380:76-89
In mammals, MT1 and MT2 melatonin receptors are high affinity G protein-coupled receptors and are thought to be involved in the integration of the melatonin signaling throughout the brain and periphery. In the present study, we describe a new melaton
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3b8b8816f2585d72be623069da9fd63
https://doi.org/10.1124/jpet.121.000785
https://doi.org/10.1124/jpet.121.000785
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2550
Melatonin exerts its classical effects of relay of the circadian rhythm through two G protein-coupled receptors, MT1 and MT2. The functions attributed to melatonin are so numerous that the action of this neurohormone should be through several protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de7828a49cc4595cbc173c7d498e0d03
https://pubmed.ncbi.nlm.nih.gov/36180694
https://pubmed.ncbi.nlm.nih.gov/36180694
Publikováno v:
Melatonin ISBN: 9781071625927
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4088ee9e765479a229d084740f53fc9a
https://doi.org/10.1007/978-1-0716-2593-4_25
https://doi.org/10.1007/978-1-0716-2593-4_25
Autor:
Preety Shabajee, Olivier Nosjean, Clémence Dupré, Céline Legros, Adeline Giganti, Chantal Brasseur, Olivier Bruno, Jean A. Boutin, Anne Bonnaud, Terrence Peter Kenakin, Damien Valour
Publikováno v:
Pharmacology Research & Perspectives, Vol 8, Iss 1, Pp n/a-n/a (2020)
Melatonin is a neurohormone that translates the circadian rhythm to the peripheral organs through a series of binding sites identified as G protein‐coupled receptors MT1 and MT2. Due to minute amounts of receptor proteins in target organs, the main
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7a9151eda474215bfd95f132e4a5c0
https://doaj.org/article/08643ceb060e4077bb6c6bb5129fe136
https://doaj.org/article/08643ceb060e4077bb6c6bb5129fe136
Autor:
Céline Legros, Olivier Bruno, Clémence Dupré, Olivier Nosjean, Jean A. Boutin, Anne Bonnaud, Adeline Giganti
Publikováno v:
European journal of pharmacology. 818
Melatonin receptors belong to the family of G-protein coupled receptors. Agonist-induced receptor activation is terminated with the recruitment of β-arrestin, which leads to receptor internalization. Furthermore, agonist binding induces a shift in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d05d2f3ae46f0659a782ff8813787976
https://pubmed.ncbi.nlm.nih.gov/29154938
https://pubmed.ncbi.nlm.nih.gov/29154938
Autor:
Céline Legros, Jean A. Boutin, Sophie Coumailleau, Philippe Delagrange, Olivier Nosjean, Anne Bonnaud, Peter Oosting, Chantal Brasseur, Olivier Bruno, Nolwenn Lepretre
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 18; Issue 7; Pages: 1347
International Journal of Molecular Sciences; Volume 18; Issue 7; Pages: 1347
The search for melatonin receptor agonists and antagonists specific towards one of the receptor subtypes will extend our understanding of the role of this system in relaying circadian information to the body. A series of compounds derived from a hit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fb6d2c83653c1580d14e792e7668e1e
http://europepmc.org/articles/PMC5535840
http://europepmc.org/articles/PMC5535840
Autor:
Nadine Nagel, Pierre Renard, François Lefoulon, Benoît Malpaux, Daniel Lesieur, Anne Bonnaud, Jean-Pierre Galizzi, Christophe Amossé, Gérald Guillaumet, Valérie Audinot, Chantal Lahaye-Brasseur, Aude Le Gall, Jean A. Boutin, François Mailliet, Marianne Rodriguez, Sandra Dromaint, Philippe Delagrange
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 367:553-561
Melatonin has a key role in the circadian rhythm relay to periphery organs. Melatonin exerts its multiple roles mainly through two seven transmembrane domain, G-coupled receptors, namely MT1 or MT2 receptors. A pharmacological characterization of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff360766f6dc705c10a917901d42f83f
https://doi.org/10.1007/s00210-003-0751-2
https://doi.org/10.1007/s00210-003-0751-2
Autor:
Philippe Delagrange, Jean-Pierre Galizzi, Perry Barrett, Valérie Audinot, Ales Balik, Marianne Rodriguez, Nadine Nagel, David G. Hazlerigg, Anne Bonnaud, Line Grandcolas, Sophie Messager, Jean A. Boutin
Publikováno v:
Biochemical pharmacology. 75(10)
In order to interpret the effects of melatonin ligands in rats, we need to determine their activity at the receptor subtype level in the corresponding species. Thus, the rat melatonin rMT(1) receptor was cloned using DNA fragments for exon 1 and 2 am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94ffce019e7f2063384f129318cecde4
https://pubmed.ncbi.nlm.nih.gov/18384758
https://pubmed.ncbi.nlm.nih.gov/18384758
Autor:
Catherine Scoul, Anne Bonnaud, Marianne Rodriguez, Olivier Nosjean, Caroline Ubeaud, Daniel Lesieur, Julien Mozo, Pierre Renard, Christophe Péan, Jean-Pierre Galizzi, Saïd Yous, Philippe Delagrange, Jean-Paul Volland, Gilles Ferry, Jean A. Boutin, Philippe Hennig
Publikováno v:
European journal of biochemistry. 271(2)
Melatonin is synthesized by an enzymatic pathway, in which arylalkylamine (serotonin) N-acetyltransferase catalyzes the rate-limiting step. A previous study reported the discovery of bromoacetyltryptamine (BAT), a new type of inhibitor of this enzyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e5fa95e0cd7ecad6d07e153f71bcda
https://pubmed.ncbi.nlm.nih.gov/14717709
https://pubmed.ncbi.nlm.nih.gov/14717709