Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Anne B, Krug"'
Autor:
Giovanna Fiore, Wolfgang Weckwarth, Kerstin Paetzold, Llucia Albertí Servera, Manuela Gies, Jakob Rosenhauer, Martina Antoniolli, Sina Nassiri, Stephan Schmeing, Steffen Dettling, Bhavesh Soni, Meher Majety, Anne B. Krug, Sabine Hoves, Monika Julia Wolf
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionPlasmacytoid dendritic cells (pDCs) are capable of triggering broad immune responses, yet, their scarcity in blood coupled to their reduced functionality in cancer, makes their therapeutic use for in situ activation or vaccination challen
Externí odkaz:
https://doaj.org/article/35fc8a3e696e4f73ac7e7d11b1b4a870
Autor:
Antonio Santos-Peral, Fabian Luppa, Sebastian Goresch, Elena Nikolova, Magdalena Zaucha, Lisa Lehmann, Frank Dahlstroem, Hadi Karimzadeh, Julia Thorn-Seshold, Elena Winheim, Ev-Marie Schuster, Gerhard Dobler, Michael Hoelscher, Beate M. Kümmerer, Stefan Endres, Kilian Schober, Anne B. Krug, Michael Pritsch, Giovanna Barba-Spaeth, Simon Rothenfusser
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The yellow fever 17D vaccine (YF17D) is highly effective but is frequently administered to individuals with pre-existing cross-reactive immunity, potentially impacting their immune responses. Here, we investigate the impact of pre-existing f
Externí odkaz:
https://doaj.org/article/0cc439cc069c4608a03f5cbc55f045c0
Autor:
Konstantin Lutz, Andrea Musumeci, Christopher Sie, Ezgi Dursun, Elena Winheim, Johannes Bagnoli, Christoph Ziegenhain, Lisa Rausch, Volker Bergen, Malte D. Luecken, Robert A. J. Oostendorp, Barbara U. Schraml, Fabian J. Theis, Wolfgang Enard, Thomas Korn, Anne B. Krug
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The ontogeny of conventional and plasmacytoid dendritic cells (DC) and how these two cell types are related is not fully known. Here the authors identify a pool of bone marrow precursor cells expressing Ly6D Siglec-H and Zbtb46 that can differentiate
Externí odkaz:
https://doaj.org/article/f5d4fd7088514584b4103c386d773afa
Autor:
Magdalena K. Scheck, Lisa Lehmann, Magdalena Zaucha, Paul Schwarzlmueller, Kristina Huber, Michael Pritsch, Giovanna Barba-Spaeth, Oliver Thorn-Seshold, Anne B. Krug, Stefan Endres, Simon Rothenfusser, Julia Thorn-Seshold
Publikováno v:
PLoS ONE, Vol 17, Iss 2 (2022)
There is an urgent need for better diagnostic and analytical methods for vaccine research and infection control in virology. This has been highlighted by recently emerging viral epidemics and pandemics (Zika, SARS-CoV-2), and recurring viral outbreak
Externí odkaz:
https://doaj.org/article/b44df890be0646e2827ad2ab10ab576a
Autor:
Lisa Rausch, Konstantin Lutz, Martina Schifferer, Elena Winheim, Rudi Gruber, Elina F. Oesterhaus, Linus Rinke, Johannes C. Hellmuth, Clemens Scherer, Maximilian Muenchhoff, Christopher Mandel, Michael Bergwelt‐Baildon, Mikael Simons, Tobias Straub, Anne B. Krug, Jan Kranich, Thomas Brocker
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 14, Pp n/a-n/a (2021)
Abstract Infection with SARS‐CoV‐2 is associated with thromboinflammation, involving thrombotic and inflammatory responses, in many COVID‐19 patients. In addition, immune dysfunction occurs in patients characterised by T cell exhaustion and sev
Externí odkaz:
https://doaj.org/article/90e56d7dcd8c4e7da4606b3b096736f2
Autor:
Elena Winheim, Linus Rinke, Konstantin Lutz, Anna Reischer, Alexandra Leutbecher, Lina Wolfram, Lisa Rausch, Jan Kranich, Paul R Wratil, Johanna E Huber, Dirk Baumjohann, Simon Rothenfusser, Benjamin Schubert, Anne Hilgendorff, Johannes C Hellmuth, Clemens Scherer, Maximilian Muenchhoff, Michael von Bergwelt-Baildon, Konstantin Stark, Tobias Straub, Thomas Brocker, Oliver T Keppler, Marion Subklewe, Anne B Krug
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10, p e1009742 (2021)
Disease manifestations in COVID-19 range from mild to severe illness associated with a dysregulated innate immune response. Alterations in function and regeneration of dendritic cells (DCs) and monocytes may contribute to immunopathology and influenc
Externí odkaz:
https://doaj.org/article/852e03dd622546c7b68aaac8583d6fbd
Autor:
Chang-Feng Chu, Florian Sabath, Silvia Fibi-Smetana, Shan Sun, Rupert Öllinger, Elfriede Noeßner, Ying-Yin Chao, Linus Rinke, Elena Winheim, Roland Rad, Anne B. Krug, Leila Taher, Christina E. Zielinski
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
COVID-19, the disease caused by SARS-CoV-2 infection, can assume a highly variable disease course, ranging from asymptomatic infection, which constitutes the majority of cases, to severe respiratory failure. This implies a diverse host immune respons
Externí odkaz:
https://doaj.org/article/a4a5a8a224bb40909430cdabe11e9302
Autor:
Johanna E Huber, Julia Ahlfeld, Magdalena K Scheck, Magdalena Zaucha, Klaus Witter, Lisa Lehmann, Hadi Karimzadeh, Michael Pritsch, Michael Hoelscher, Frank vonSonnenburg, Andrea Dick, Giovanna Barba‐Spaeth, Anne B Krug, Simon Rothenfußer, Dirk Baumjohann
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 5, Pp n/a-n/a (2020)
Abstract Objectives T follicular helper (Tfh) cells are the principal T helper cell subset that provides help to B cells for potent antibody responses against various pathogens. In this study, we took advantage of the live‐attenuated yellow fever v
Externí odkaz:
https://doaj.org/article/8c649ab8f7184f9ab04b40801726e6b0
Autor:
Taku Ito-Kureha, Cristina Leoni, Kayla Borland, Giulia Cantini, Marian Bataclan, Rebecca N. Metzger, Gregor Ammann, Anne B. Krug, Annalisa Marsico, Stefanie Kaiser, Stefan Canzar, Stefan Feske, Silvia Monticelli, Julian König, Vigo Heissmeyer
Publikováno v:
Nat. Immunol. 23, 1208-1221 (2022)
T cell antigen-receptor (TCR) signaling controls the development, activation and survival of T cells by involving several layers and numerous mechanisms of gene regulation. N6-methyladenosine (m6A) is the most prevalent messenger RNA modification aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc76b0ae4aab565218a3b16004db381
https://doi.org/10.1038/s41590-022-01268-1
https://doi.org/10.1038/s41590-022-01268-1
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Colorectal cancer (CRC) is one of the most common cancers and a major cause of mortality. Mice with truncating Apc germline mutations have been used as a standard model of CRC, but most of the Apc-mutated lines develop multiple tumors in the proximal
Externí odkaz:
https://doaj.org/article/950eafcbeb664975a20d8835d5315b61