Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Anne Aublin-Gex"'
Autor:
Laure Perrin-Cocon, Pierre-Olivier Vidalain, Clémence Jacquemin, Anne Aublin-Gex, Keedrian Olmstead, Baptiste Panthu, Gilles Jeans Philippe Rautureau, Patrice André, Piotr Nyczka, Marc-Thorsten Hütt, Nivea Amoedo, Rodrigue Rossignol, Fabian Volker Filipp, Vincent Lotteau, Olivier Diaz
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Many cancers fuel their rapid growth by replacing glucokinase with its higher affinity isoenzyme, hexokinase 2 (HK2), making HK2 an attractive drug target. In this study, Perrin-Cocon and Vidalain et al. use CRISPR/Cas-9 gene editing to reverse this
Externí odkaz:
https://doaj.org/article/a519b0af2fba49868394944910f843d0
Autor:
Benoît de Chassey, Anne Aublin-Gex, Alessia Ruggieri, Laurène Meyniel-Schicklin, Fabrine Pradezynski, Nathalie Davoust, Thibault Chantier, Lionel Tafforeau, Philippe-Emmanuel Mangeot, Claire Ciancia, Laure Perrin-Cocon, Ralf Bartenschlager, Patrice André, Vincent Lotteau
Publikováno v:
PLoS Pathogens, Vol 9, Iss 7, p e1003440 (2013)
Influenza A NS1 and NS2 proteins are encoded by the RNA segment 8 of the viral genome. NS1 is a multifunctional protein and a virulence factor while NS2 is involved in nuclear export of viral ribonucleoprotein complexes. A yeast two-hybrid screening
Externí odkaz:
https://doaj.org/article/47caec1552524dd9983884cad12f4662
Publikováno v:
Immuno
Immuno, MDPI, 2021, 1 (1), pp.1-14. ⟨10.3390/immuno1010001⟩
Immuno, 2021, 1 (1), pp.1-14. ⟨10.3390/immuno1010001⟩
Immuno, MDPI, 2021, 1 (1), pp.1-14. ⟨10.3390/immuno1010001⟩
Immuno, 2021, 1 (1), pp.1-14. ⟨10.3390/immuno1010001⟩
International audience; Immunometabolism is a relatively new field of research that aims at understanding interconnections between the immune system and cellular metabolism. This is now well-documented for innate immune cells of the myeloid lineage s
Publikováno v:
The Role of Toll-Like Receptor 4 in Infectious and Non Infectious Inflammation ISBN: 9783030563189
Cell metabolism sustains the generation of energy, the modulation of cell signaling, and the production of molecular blocks for cell maintenance and/or proliferation. Immune cells not only require energy to survive but also need to adapt their metabo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60af8b35e0a193b35ce6df06d89710cd
https://doi.org/10.1007/978-3-030-56319-6_11
https://doi.org/10.1007/978-3-030-56319-6_11
Autor:
Marc-Thorsten Hütt, Keedrian I. Olmstead, Pierre-Olivier Vidalain, Rautureau Gjp, Rodrigue Rossignol, Fabian V. Filipp, Piotr Nyczka, Olivier Diaz, Lotteau, Baptiste Panthu, Laure Perrin-Cocon, Anne Aublin-Gex, Clémence Jacquemin, Patrice Andre, Nivea Dias Amoedo
Hexokinases catalyze the first step of glycolysis by phosphorylating glucose. In the liver, normal hepatocytes express the low-affinity hexokinase 4, also known as glucokinase (GCK), which is adapting hepatocyte function to glycaemia. Conversely, hep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80aaf425e11eb32f85f9c8c8c28497f4
https://doi.org/10.1101/2020.03.13.973321
https://doi.org/10.1101/2020.03.13.973321
Autor:
Laure Perrin-Cocon, Cindy Kundlacz, Clémence Jacquemin, Xavier Hanoulle, Anne Aublin-Gex, Marianne Figl, Jeremy Manteca, Patrice André, Pierre-Olivier Vidalain, Vincent Lotteau, Olivier Diaz
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2022, 23 (2), pp.919. ⟨10.3390/ijms23020919⟩
International Journal of Molecular Sciences, Vol 23, Iss 919, p 919 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 919
International Journal of Molecular Sciences, 2022, 23 (2), pp.919. ⟨10.3390/ijms23020919⟩
International Journal of Molecular Sciences, Vol 23, Iss 919, p 919 (2022)
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 919
International audience; Hepatitis C virus (HCV) relies on cellular lipid metabolism for its replication, and actively modulates lipogenesis and lipid trafficking in infected hepatocytes. This translates into an intracellular accumulation of triglycer
Autor:
Laurène Meyniel-Schicklin, Patrice Andre, Benoît de Chassey, Anne Aublin-Gex, Thibaut Chantier, Vincent Lotteau, Vincent Navratil
Publikováno v:
EMBO reports; Vol 14
Virus–host interactomes are instrumental to understand global perturbations of cellular functions induced by infection and discover new therapies. The construction of such interactomes is, however, technically challenging and time consuming. Here w
Autor:
Vincent Lotteau, Barbara Gineys, Christine Dolmazon, Fabienne Archer, Alexandra Erny, Caroline Leroux, Sophie Desloire, Anne Aublin-Gex, Margaux Monot
Publikováno v:
Journal of Virology
Journal of Virology, 2015, 89 (16), pp.8462-8473. ⟨10.1128/JVI.00590-15⟩
Journal of Virology, American Society for Microbiology, 2015, 89 (16), pp.8462-8473. ⟨10.1128/JVI.00590-15⟩
Journal of Virology, 2015, 89 (16), pp.8462-8473. ⟨10.1128/JVI.00590-15⟩
Journal of Virology, American Society for Microbiology, 2015, 89 (16), pp.8462-8473. ⟨10.1128/JVI.00590-15⟩
Ovine pulmonary adenocarcinoma is a naturally occurring lung cancer in sheep induced by the Jaagsiekte sheep retrovirus (JSRV). Its envelope glycoprotein (Env) carries oncogenic properties, and its expression is sufficient to induce in vitro cell tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75c7601cfd71cce9fd611a4ad00cf819
https://hal.science/hal-01953669
https://hal.science/hal-01953669
Autor:
Anne Aublin-Gex, Nathalie Davoust, Vincent Lotteau, Alessia Ruggieri, Thibault Chantier, Ralf Bartenschlager, Benoît de Chassey, Laurène Meyniel-Schicklin, Lionel Tafforeau, Patrice Andre, Fabrine Pradezynski, Philippe E. Mangeot, Laure Perrin-Cocon, Claire Ciancia
Publikováno v:
P L o S Pathogens, 9 (7
PLoS Pathogens, Vol 9, Iss 7, p e1003440 (2013)
PLoS Pathogens
PLoS Pathogens, Vol 9, Iss 7, p e1003440 (2013)
PLoS Pathogens
Influenza A NS1 and NS2 proteins are encoded by the RNA segment 8 of the viral genome. NS1 is a multifunctional protein and a virulence factor while NS2 is involved in nuclear export of viral ribonucleoprotein complexes. A yeast two-hybrid screening
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c32a5fa9a3791aeca9e72416d58aa888
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/147701
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/147701
Autor:
Benoît de Chassey, Anne Aublin-Gex, Vincent Lotteau, Patrice Andre, Laurène Meyniel-Schicklin
Publikováno v:
Current opinion in virology. 2(5)
Viruses are recurrent socio economical and health problems each year worldwide. Current drugs are mainly directed against viral components and select resistant strains that urge the need to develop new antiviral therapeutics. High-throughput screenin