Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Anne Astier"'
Autor:
Maximilian Richter, Roma Yumul, Kamola Saydaminova, Hongjie Wang, Michael Gough, Audrey Baldessari, Roberto Cattaneo, Frank Lee, Chung-Huei Katherine Wang, Haishan Jang, Anne Astier, Ajay Gopal, Darrick Carter, André Lieber
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Rituximab is a mouse/human chimeric monoclonal antibody targeted toward CD20. It is efficient as first-line therapy of CD20-positive B-cell malignancies. However, a large fraction of treated patients relapse with rituximab-resistant disease. So far,
Externí odkaz:
https://doaj.org/article/0093c282ecfb45288f89602b78f31362
Autor:
Manon Galoppin, Saniya Kari, Sasha Soldati, Arindam Pal, Manon Rival, Britta Engelhardt, Anne Astier, Eric Thouvenot
Publikováno v:
Galoppin, Manon; Kari, Saniya; Soldati, Sasha; Pal, Arindam; Rival, Manon; Engelhardt, Britta; Astier, Anne; Thouvenot, Eric (2022). Full spectrum of vitamin D immunomodulation in multiple sclerosis: mechanisms and therapeutic implications. Brain Communications, 4(4), fcac171. Oxford University Press 10.1093/braincomms/fcac171
Brain Communications
Brain Communications, Oxford University Press on behalf of the Guarantors of Brain, 2022, 4 (4), pp.fcac171. ⟨10.1093/braincomms/fcac171⟩
Brain Communications
Brain Communications, Oxford University Press on behalf of the Guarantors of Brain, 2022, 4 (4), pp.fcac171. ⟨10.1093/braincomms/fcac171⟩
Vitamin D deficiency has been associated with the risk of multiple sclerosis, disease activity and progression. Results from in vitro experiments, animal models and analysis of human samples from randomized controlled trials provide comprehensive dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8057c30423423e3a78b35fa205dacd7b
https://doi.org/10.1093/braincomms/fcac171
https://doi.org/10.1093/braincomms/fcac171
Autor:
Adriano G. Rossi, Florian Wollweber, Marta Canel, Johanna Lilja, Barry McCormick, Leo M. Carlin, Jennifer M Felton, Takehiko Sasaki, Melina Michael, Sonja Vermeren, Laura J. Norton, Anne Astier, Helen E. Craig, Ian Dransfield, Ingeborg Hers, Johanna Ivaska, Julia Y. Chu, Matilda Toivakka
Publikováno v:
The Journal of Immunology Author Choice
McCormick, B, Craig, H E, Chu, J Y, Carlin, L M, Canel, M, Wollweber, F, Toivakka, M, Michael, M, Astier, A L, Norton, L, Lilja, J, Felton, J M, Sasaki, T, Ivaska, J, Hers, I, Dransfield, I, Rossi, A G & Vermeren, S 2019, ' A negative feedback loop regulates integrin inactivation and promotes neutrophil recruitment to inflammatory sites ', Journal of Immunology, vol. 203, no. 9 . https://doi.org/10.4049/jimmunol.1900443
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2019, 203 (6), pp.1579-1588. ⟨10.4049/jimmunol.1900443⟩
McCormick, B, Craig, H E, Chu, J Y, Carlin, L M, Canel, M, Wollweber, F, Toivakka, M, Michael, M, Astier, A L, Norton, L, Lilja, J, Felton, J M, Sasaki, T, Ivaska, J, Hers, I, Dransfield, I, Rossi, A G & Vermeren, S 2019, ' A Negative Feedback Loop Regulates Integrin Inactivation and Promotes Neutrophil Recruitment to Inflammatory Sites ', Journal of Immunology, vol. 203, no. 6, pp. 1579-1588 . https://doi.org/10.4049/jimmunol.1900443
McCormick, B, Craig, H E, Chu, J Y, Carlin, L M, Canel, M, Wollweber, F, Toivakka, M, Michael, M, Astier, A L, Norton, L, Lilja, J, Felton, J M, Sasaki, T, Ivaska, J, Hers, I, Dransfield, I, Rossi, A G & Vermeren, S 2019, ' A negative feedback loop regulates integrin inactivation and promotes neutrophil recruitment to inflammatory sites ', Journal of Immunology, vol. 203, no. 9 . https://doi.org/10.4049/jimmunol.1900443
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2019, 203 (6), pp.1579-1588. ⟨10.4049/jimmunol.1900443⟩
McCormick, B, Craig, H E, Chu, J Y, Carlin, L M, Canel, M, Wollweber, F, Toivakka, M, Michael, M, Astier, A L, Norton, L, Lilja, J, Felton, J M, Sasaki, T, Ivaska, J, Hers, I, Dransfield, I, Rossi, A G & Vermeren, S 2019, ' A Negative Feedback Loop Regulates Integrin Inactivation and Promotes Neutrophil Recruitment to Inflammatory Sites ', Journal of Immunology, vol. 203, no. 6, pp. 1579-1588 . https://doi.org/10.4049/jimmunol.1900443
Key Points A negative feedback loop, integrin–PI3K–ARAP3–integrin, controls integrin inactivation. Integrin inactivation promotes neutrophil transendothelial migration and recruitment.
Neutrophils are abundant circulating leukocytes that a
Neutrophils are abundant circulating leukocytes that a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a466483943b030926eccf708404293
http://europepmc.org/articles/PMC6731454
http://europepmc.org/articles/PMC6731454
Autor:
Julia Y. Chu, Sonja Vermeren, Kruthika Sundaram, Ian Dransfield, Hannah Garside, Anne Astier, Utsa Karmakar, Carsten G. Hansen
Publikováno v:
Karmakar, U, Chu, J, Sundaram, K, Astier, A, Garside, H, Hansen, C G, Dransfield, I & Vermeren, S 2021, ' Immune complex-induced apoptosis and concurrent immune complex clearance are anti-inflammatory neutrophil functions ', Cell Death and Disease . https://doi.org/10.1038/s41419-021-03528-8
Cell Death and Disease
Cell Death and Disease, Nature Publishing Group, 2021, 12 (4), ⟨10.1038/s41419-021-03528-8⟩
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 4, Pp 1-13 (2021)
Cell Death and Disease, 2021, 12, pp.296. ⟨10.1038/s41419-021-03528-8⟩
Cell Death and Disease
Cell Death and Disease, Nature Publishing Group, 2021, 12 (4), ⟨10.1038/s41419-021-03528-8⟩
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 4, Pp 1-13 (2021)
Cell Death and Disease, 2021, 12, pp.296. ⟨10.1038/s41419-021-03528-8⟩
Persistent neutrophilic inflammation drives host damage in autoimmune diseases that are characterized by abundant immune complexes. Insoluble immune complexes (iICs) potently activate pro-inflammatory neutrophil effector functions. We and others have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::520f49e46c9da8740178f10ef7e53310
https://www.pure.ed.ac.uk/ws/files/202899200/Karmakar_et_al_2021_Cell_Death_Disease.pdf
https://www.pure.ed.ac.uk/ws/files/202899200/Karmakar_et_al_2021_Cell_Death_Disease.pdf
Publikováno v:
Eyoh, E, McCallum, P, Killick, J, Amanfo, S A, Mutapi, F & Astier, A 2019, ' The anthelmintic drug Praziquantel promotes human Tr1 differentiation ', Immunology and Cell Biology . https://doi.org/10.1111/imcb.12229
Immunology and Cell Biology
Immunology and Cell Biology, Nature Publishing Group, 2019, 97 (5), pp.512-518. ⟨10.1111/imcb.12229⟩
Immunology and Cell Biology
Immunology and Cell Biology, Nature Publishing Group, 2019, 97 (5), pp.512-518. ⟨10.1111/imcb.12229⟩
Praziquantel (PZQ) is an anthelminthic human and veterinary drug used to treat trematode and cestode worms. Changes in immune responses have been demonstrated in humans following curative PZQ treatment of schistosome infections. These changes have be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a00100c48d3f0711bb8911a860618646
https://www.pure.ed.ac.uk/ws/files/78388660/AAM_The_anthelmintic_drug_Praziquantel....docx
https://www.pure.ed.ac.uk/ws/files/78388660/AAM_The_anthelmintic_drug_Praziquantel....docx
Autor:
Sarah E. M. Howie, Ian Dransfield, Siobhan Ni Choileain, Mario Gomez-Salazar, Joanne Hay, Owen R. Hugues, Sonja Vermeren, Matthieu Vermeren, Anna Williams, Cécile Bénézech, Anne Astier, Joëlle Thomas
Publikováno v:
Science Signaling
Science Signaling, American Association for the Advancement of Science, 2017, 10 (502), pp.eaah6163. ⟨10.1126/scisignal.aah6163⟩
Ni Choileain, S, Hay, J, Thomas, J, Williams, A, Vermeren, M M, Benezech, C, Gomez-Salazar, M, Hugues, O R, Vermeren, S, Howie, S E M, Dransfield, I & Astier, A L 2017, ' TCR-stimulated changes in cell surface CD46 expression generate type 1 regulatory T cells ', Science Signaling, vol. 10, no. 502, eaah6163 . https://doi.org/10.1126/scisignal.aah6163
Science Signaling, American Association for the Advancement of Science, 2017, 10 (502), pp.eaah6163. ⟨10.1126/scisignal.aah6163⟩
Ni Choileain, S, Hay, J, Thomas, J, Williams, A, Vermeren, M M, Benezech, C, Gomez-Salazar, M, Hugues, O R, Vermeren, S, Howie, S E M, Dransfield, I & Astier, A L 2017, ' TCR-stimulated changes in cell surface CD46 expression generate type 1 regulatory T cells ', Science Signaling, vol. 10, no. 502, eaah6163 . https://doi.org/10.1126/scisignal.aah6163
A lack of regulatory T cell function is a critical factor in the pathogenesis of autoimmune diseases, such as multiple sclerosis (MS). Ligation of the complement regulatory protein CD46 facilitates the differentiation of T helper 1 (TH1) effector cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e95a07b67e0dccaf94e6faeac5b2ea2b
https://doi.org/10.1126/scisignal.aah6163
https://doi.org/10.1126/scisignal.aah6163
Publikováno v:
Seminars in Immunopathology
Seminars in Immunopathology, 2017, Epub ahead of print. ⟨10.1007/s00281-017-0644-y⟩
Seminars in Immunopathology, Springer Verlag, 2017, Epub ahead of print. ⟨10.1007/s00281-017-0644-y⟩
Killick, J, Morisse, G, Sieger, D & Astier, A 2017, ' Complement as a regulator of adaptive immunity ', Seminars in Immunopathology . https://doi.org/10.1007/s00281-017-0644-y
Seminars in Immunopathology, 2017, Epub ahead of print. ⟨10.1007/s00281-017-0644-y⟩
Seminars in Immunopathology, Springer Verlag, 2017, Epub ahead of print. ⟨10.1007/s00281-017-0644-y⟩
Killick, J, Morisse, G, Sieger, D & Astier, A 2017, ' Complement as a regulator of adaptive immunity ', Seminars in Immunopathology . https://doi.org/10.1007/s00281-017-0644-y
International audience; The complement system is an ancient and evolutionarily conserved effector system comprising in mammals over 50 circulating and membrane bound proteins. Complement has long been described as belonging to the innate immune syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36bb4cd7bcf2bec841883ddf573818ac
https://www.hal.inserm.fr/inserm-01593213
https://www.hal.inserm.fr/inserm-01593213
Publikováno v:
Immunology
Immunology, Wiley, 2015, 144 (3), pp.453-460. ⟨10.1111/imm.12391⟩
Hay, J, Carter, D, Lieber, A & Astier, A L 2015, ' Recombinant Ad35 adenoviral proteins as potent modulators of human T cell activation ', Immunology, vol. 144, no. 3, pp. 453-460 . https://doi.org/10.1111/imm.12391
Immunology, Wiley, 2015, 144 (3), pp.453-460. ⟨10.1111/imm.12391⟩
Hay, J, Carter, D, Lieber, A & Astier, A L 2015, ' Recombinant Ad35 adenoviral proteins as potent modulators of human T cell activation ', Immunology, vol. 144, no. 3, pp. 453-460 . https://doi.org/10.1111/imm.12391
The protein CD46 protects cells from complement attack by regulating cleavage of C3b and C3d. CD46 also regulates the adaptive immune response by controlling T cell activation and differentiation. Co-engagement of the T cell receptor and CD46 notably
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8932cea7de8622f07f5a312af39944f
https://doi.org/10.1111/imm.12391
https://doi.org/10.1111/imm.12391
Autor:
Roma Yumul, Hongjie Wang, Michael Gough, Darrick Carter, Haishan Jang, André Lieber, Audrey Baldessari, Roberto Cattaneo, Anne Astier, Ajay K. Gopal, Frank Lee, Chung Huei Katherine Wang, Maximilian Richter, Kamola Saydaminova
Publikováno v:
Molecular Therapy-Methods and Clinical Development
Molecular Therapy-Methods and Clinical Development, Nature Publishing Group, 2016, 3, pp.16013. ⟨10.1038/mtm.2016.13⟩
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy-Methods and Clinical Development, Nature Publishing Group, 2016, 3, pp.16013. ⟨10.1038/mtm.2016.13⟩
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Molecular Therapy. Methods & Clinical Development
Rituximab is a mouse/human chimeric monoclonal antibody targeted toward CD20. It is efficient as first-line therapy of CD20-positive B-cell malignancies. However, a large fraction of treated patients relapse with rituximab-resistant disease. So far,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168e2e8098fe6fccad9bb3d283e2bda4
https://hal.archives-ouvertes.fr/hal-02322334
https://hal.archives-ouvertes.fr/hal-02322334
Autor:
David A. Hafler, Anne Astier
Publikováno v:
Journal of Neuroimmunology
Journal of Neuroimmunology, Elsevier, 2007, 191 (1-2), pp.70-78. ⟨10.1016/j.jneuroim.2007.09.018⟩
Journal of Neuroimmunology, Elsevier, 2007, 191 (1-2), pp.70-78. ⟨10.1016/j.jneuroim.2007.09.018⟩
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). In the recent years, accumulating evidence has supported an immunosuppressive role for regulatory T cells (Tregs). Most studies in the context of au
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::331554d203ffac8b0a532f9c173c70b0
https://doi.org/10.1016/j.jneuroim.2007.09.018
https://doi.org/10.1016/j.jneuroim.2007.09.018