Výsledky vyhledávání - "Anne Arnould"

Study of shielding options for lower ports for mitigation of neutron environment and shutdown dose inside the ITER cryostat

Autor: Raul Pampin, Flavien Sabourin, E. Polunovskiy, Rafael Juarez, N. Casal, Fernando Mota, Anne Arnould, Fabio Moro, Alejandro Suarez, A. Martin

Publikováno v: Fusion Engineering and Design. :1408-1411

Mitigation of the neutron environment inside the cryostat, and of the subsequent decay gamma dose field from activated materials, is necessary in order to reduce heating of coils and occupational exposure, thereby facilitating smooth operation and ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0a958b91dcd4dc6a672df2c145db1be3
https://doi.org/10.1016/j.fusengdes.2015.12.010

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Increased Fetal and Extramedullary Hematopoiesis in Fas-Deficient C57BL/6-lpr/lpr Mice

Autor: Florence Vasseur, Géraldine Moreau, Michel Dy, Elke Schneider, Sophie Ezine, Anne Arnould, Naushad Khodabaccus

Publikováno v: Blood. 94:2613-2621

In this study, we examined the consequences of Fas deficiency on hematopoiesis in C57BL/6-lpr/lpr mice. We found a striking extramedullary increase in hematopoietic progenitor cells, comprising erythroid and nonerythroid lineages alike. These modific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::096e74e21c2fea36f640d4c5fad61b3d
https://doi.org/10.1182/blood.v94.8.2613.420k33_2613_2621

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Modulation of histidine decarboxylase activity and cytokine synthesis in human leukemic cell lines

Autor: Maria Pacilio, Michael Bodger, Elke Schneider, François Machavoine, Anne Arnould, Patrick Mayeux, Michel Dy, Olivier Hermine

Publikováno v: Experimental Hematology. 27:1295-1305

In the present study, we show that UT7D1 cells, derived from the pluripotent cell line UT7, express high levels of histidine decarboxylase (HDC) mRNA spontaneously. These cells conserve the ability to differentiate into megakaryocytes upon stimulatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ab286fa68e712f11150024d1665e2e8d
https://doi.org/10.1016/s0301-472x(99)00070-3

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IL-3-induced coexpression of histidine decarboxylase, IL-4 and IL-6 mRNA by murine basophil precursors

Autor: Janine Breton-Gorius, Anne Arnould, Josette Guichard, Elke Schneider, François M. Lemoine, Dy Michel, François Machavoine, Elisabeth M. Cramer

Publikováno v: Experimental Hematology. 27:1010-1018

Murine low-density bone marrow cells sorted from the blast cell window on the basis of high rhodamine-123 retention (Rh-bright), are highly enriched in histamine-, IL-4-, and IL-6-producing cells. We established by in situ hybridization that up to 50

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c48ccb736f49a21a9e686554c65478d6
https://doi.org/10.1016/s0301-472x(99)00039-9

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Prognostic value of vertebral lesions detected by magnetic resonance imaging in patients with stage I multiple myeloma

Autor: Jean-Claude Brouet, Catherine Bergot, Xavier Mariette, Jean-Paul Fermand, Anne-Marie Zagdanski, Ali Guermazi, Jacques Frija, Anne Arnould

Publikováno v: British Journal of Haematology. 104:723-729

We assessed the role of spinal magnetic resonance imaging (MRI) and bone densitometry as prognostic factors in patients with asymptomatic stage I multiple myeloma (MM) and negative skeletal survey. 55 consecutive patients underwent spinal MRI and 41

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4131dfba1efa61988260e70d4ff219b3
https://doi.org/10.1046/j.1365-2141.1999.01244.x

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IL-4-producing NK T cells are biased towards IFN-γ production by IL-12. Influence of the microenvironment on the functional capacities of NK T cells

Autor: Maria Leite-de-Moraes, Corinne Garcia, Martine Papiernik, Michel Dy, Géraldine Moreau, François Machavoine, Anne Arnould

Publikováno v: European Journal of Immunology
European Journal of Immunology, 1998, 28 (5), pp.1507-1515. ⟨10.1002/(SICI)1521-4141(199805)28:053.0.CO;2-F⟩

International audience; NK T cells are an unusual T lymphocyte subset capable of promptly producing several cytokines after stimulation, in particular IL-4, thus suggesting their influence in Th2 lineage commitment. In this study we demonstrate that,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f24465dc14fc3eb998c10ab99e1b8257
https://doi.org/10.1002/(sici)1521-4141(199805)28:05<1507::aid-immu1507>3.0.co

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Thrombopoietin induces histidine decarboxylase gene expression in c-mpl transfected UT7 cells

Autor: Michel Dy, Elke Schneider, François Machavoine, Dominique Dumenil, Malvyne Rolli-Derkinderen, Michel Arock, Anne Arnould, Michael Bodger, Najet Debili, Maria Pacilio

Publikováno v: Biochemical and biophysical research communications. 285(5)

The leukemic cell line UT7 is endowed with both megakaryocyte and basophil differentiation potential, as judged by its capacity to respond to PMA by displaying megakaryocytic and basophilic markers and to produce histamine by neosynthesis. Herein, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353802e6c581704e16a7f0d0ece88474
https://pubmed.ncbi.nlm.nih.gov/11478766

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Hematopoietic progenitors and interleukin-3-dependent cell lines synthesize histamine in response to calcium ionophore

Autor: Anne Arnould, Hermann Ziltener, Elke Schneider, Michel Dy, François Machavoine, Frangois M. Lemoine

Publikováno v: Blood. 87(8)

The calcium ionophore A23187 promotes histamine synthesis in murine bone marrow cells by increasing the expression of mRNA encoding histidine decarboxylase (HDC), the histamine-forming enzyme. The cells responsible for this biological activity copuri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ffa3025533e910e2864f22745d6fc9b
https://pubmed.ncbi.nlm.nih.gov/8605330

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In vitro T cell unresponsiveness following low-dose injection of anti-CD3 MoAb

Autor: F. Lepault, Maria Leite-de-Moraes, Anne Arnould, Lucienne Chatenoud, Elke Schneider, Michel Dy, François Machavoine, A. Ben-Amor

Publikováno v: Clinical and experimental immunology. 103(3)

SUMMARY Anti-CD3 MoAb treatment is widely used as an immunosuppressive therapy. In the present study we examined the in vitro T cell response in mice having received 24 h before a single i.v. injection of 10 μg of anti-CD3 MoAb. We found that spleno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02685c9e9f1352269153680f398901f2
https://pubmed.ncbi.nlm.nih.gov/8608651

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Ligand-activated natural killer T lymphocytes promptly produce IL-3 and GM-CSF in vivo: relevance to peripheral myeloid recruitment

Autor: Anne Arnould, Mariette Lisbonne, André Herbelin, Michel Dy, Elke Schneider, François Machavoine, Maria Leite-de-Moraes

Publikováno v: European Journal of Immunology. 32:1897

Natural killer (NK) T cells are prominent for their prompt IL-4 and IFN-gamma production upon TCR ligation that enables them to influence acquired immune responses. In the present study we provide evidence that the regulatory functions of this partic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c05b4c68561ce9f458ce37af45f02bb1
https://doi.org/10.1002/1521-4141(200207)32:7<1897::aid-immu1897>3.0.co

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