Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Anne A. Leyrat"'
Autor:
Alex A. Pollen, Mahdi Golkaram, Neha Rani, Arnold R. Kriegstein, Beatriz Alvarado, Kylie Huch, Tomasz J. Nowakowski, Anne A. Leyrat, Jay A. A. West, Hongjun Zhou, Linda R. Petzold, Kenneth S. Kosik
Publikováno v:
Nature neuroscience, vol 21, iss 12
Nature neuroscience
Nowakowski, TJ; Rani, N; Golkaram, M; Zhou, HR; Alvarado, B; Huch, K; et al.(2018). Regulation of cell-type-specific transcriptomes by microRNA networks during human brain development. Nature Neuroscience, 21(12), 1784-1792. doi: 10.1038/s41593-018-0265-3. UC Santa Barbara: Retrieved from: http://www.escholarship.org/uc/item/0fn1k4g2
Nature neuroscience
Nowakowski, TJ; Rani, N; Golkaram, M; Zhou, HR; Alvarado, B; Huch, K; et al.(2018). Regulation of cell-type-specific transcriptomes by microRNA networks during human brain development. Nature Neuroscience, 21(12), 1784-1792. doi: 10.1038/s41593-018-0265-3. UC Santa Barbara: Retrieved from: http://www.escholarship.org/uc/item/0fn1k4g2
© 2018, The Author(s), under exclusive licence to Springer Nature America, Inc. MicroRNAs (miRNAs) regulate many cellular events during brain development by interacting with hundreds of mRNA transcripts. However, miRNAs operate nonuniformly upon the
Autor:
Mohammed A. Mostajo-Radji, Alex A. Pollen, Tomasz J. Nowakowski, Xiaohui Wang, Johain Ryad Ounadjela, Beatriz Alvarado, Dmitry Velmeshev, Jay A. A. West, Elizabeth Di Lullo, Maximilian Haeussler, Arnold R. Kriegstein, W. James Kent, Aparna Bhaduri, Siyuan John Liu, Anne A. Leyrat, Carmen Sandoval-Espinosa, Joe Shuga, Daniel A. Lim
Publikováno v:
Science. 358:1318-1323
Building a brain The human brain is built in an inside-out manner as a series of layers. Although progenitor cells spin off new neurons in a seemingly organized fashion, the devil is in the details. Nowakowski et al. analyzed the transcriptomes of si
Autor:
Diane Jung, Carlos E. Cunha, Georgia Panagiotakos, Nils Lovegren, Andreas Mayer, Anne A. Leyrat, Jay A. A. West, Michael L. Gonzales, Arturo Alvarez-Buylla, Lukasz Szpankowski, Tomasz J. Nowakowski, Beatriz Alvarado, Dmitry Velmeshev, Jiadong Chen, Simone Mayer, Ugomma C. Eze, Arnold R. Kriegstein, Emmy Li, Mercedes F. Paredes, Shaohui Wang, Aparna Bhaduri, Arpana Arjun, Alex A. Pollen
Publikováno v:
Neuron, vol 102, iss 1
Neuron
Neuron
In the developing human neocortex, progenitor cells generate diverse cell types prenatally. Progenitor cells and newborn neurons respond to signaling cues, including neurotransmitters. While single-cell RNA sequencing has revealed cellular diversity,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa26330944a1e30cfa4ff301709adc6
https://escholarship.org/uc/item/7sg4h391
https://escholarship.org/uc/item/7sg4h391
Autor:
Tomasz J. Nowakowski, Kylie Huch, Arnold R. Kriegstein, Neha Rani, Beatriz Alvarado, Jay A. A. West, Mahdi Golkaram, Alex A. Pollen, Hongjun Zhou, Anne A. Leyrat, Kenneth S. Kosik, Linda R. Petzold
MicroRNAs (miRNAs) regulate many cellular events by regulating hundreds of mRNA transcripts. However, it is unclear how miRNA-mRNA interactions are contextualized into the framework of transcriptional heterogeneity among closely related cells of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ffcb3f33eeca9fbacf9d3b6e3c566c5
https://doi.org/10.1101/412510
https://doi.org/10.1101/412510
Autor:
Win Hwang, Michael C Norris, Marcos Lam, Justin Axsom, Brian Fowler, Aik Ooi, Leo Lee, Ming-Fang Zhou, Tony Shuga, Rudy Yeung, Xiaohui Wang, Eng-Seng Ong, Chee-Sing Chin, Ninez Delos Angeles, Cassandra Greene, Cate Larsen, Henry Choi, Chad Sanada, Lukasz Szpankowski, Kenneth J. Livak, Ilona Holcomb, Chong T. Lu, Naveen Ramalingam, Joe Shuga, Anne A. Leyrat, Zaw Htoo, Kyle Hukari, Wiganda Yorza, Myo Thu Maung, Marc A. Unger, Jay A. A. West, Stolarczyk Craig B, Zhong-Wei Shen, Chang-Chee Poh, Chris Cesar, Naga Sai Gopi Krishna Devaraju, Michael L. Gonzales
Publikováno v:
Frontiers in Bioengineering and Biotechnology. 5
Publikováno v:
Nature Protocols. 9:1713-1726
Time-dependent analysis of dynamic processes in single live cells is a revolutionary technique for the quantitative studies of signaling networks. Here we describe an experimental pipeline and associated protocol that incorporate microfluidic cell cu
Autor:
Jay A. A. West, Neevan Ramalingam, Anne A. Leyrat, Lukasz Szpankowski, Ali Asgar S. Bhagat, Y.F. Lee, Ninez Delos Angeles, A. Wu
Publikováno v:
Annals of Oncology. 27
Autor:
Lukasz Szpankowski, Joe Shuga, Kenneth J. Livak, Chris Cesar, Tony Shuga, Zaw Htoo, Eng-Seng Ong, Marc A. Unger, Wiganda Yorza, Justin Axsom, Michael C Norris, Anne A. Leyrat, Ninez Delos Angeles, Xiaohui Wang, Jay A. A. West, Stolarczyk Craig B, Michael L. Gonzales, Ming-Fang Zhou, Myo Thu Maung, Rudy Yeung, Chong T. Lu, Chang-Chee Poh, Naga Sai Gopi Krishna Devaraju, Win Hwang, Marcos Lam, Cassandra Greene, Ilona Holcomb, Aik Ooi, Kyle Hukari, Leo Lee, Chee-Sing Chin, Zhong-Wei Shen, Henry Choi, Brian Fowler, Chad Sanada, Naveen Ramalingam, Cate Larsen
Publikováno v:
Frontiers in Bioengineering and Biotechnology
Frontiers in Bioengineering and Biotechnology, Vol 4 (2016)
Frontiers in Bioengineering and Biotechnology, Vol 4 (2016)
The study of single cells has evolved over the past several years to include expression and genomic analysis of an increasing number of single cells. Several studies have demonstrated wide-spread variation and heterogeneity within cell populations of
Autor:
Andrew Wu, Jay A. A. West, Brian Fowler, David King, Chad Sanada, Mark Lynch, Naveen Ramalingam, Anne A. Leyrat, Yi Fang Lee, Lukasz Szpankowski, Ali Asgar S. Bhagat, Yoon Sim Yap, Ninez Delos Angeles, Kyle Hukari
Publikováno v:
Cancer Research. 79:LB-326
Background Understanding the genetic heterogeneity of circulating immune and tumors cells at single-cell resolution will enable one to decipher the interplay between cancer and immune cells, and ultimately lead to better design of immunotherapy assay
Autor:
Craig B. Lowe, Ian T. Fiddes, Sofie R. Salama, Madeline G. Andrews, Olivia S. Meyerson, Elizabeth Di Lullo, Jay A. A. West, Bryan J Pavlovic, Max L. Dougherty, Joe Shuga, Arnold R. Kriegstein, Mohammed A. Mostajo-Radji, Aparna Bhaduri, Alex A. Pollen, Beatriz Alvarado, Marina Bershteyn, David Haussler, Melanie Bedolli, Tomasz J. Nowakowski, Evan E. Eichler, Anne A. Leyrat, Zev N. Kronenberg
Publikováno v:
Cell, vol 176, iss 4
Direct comparisons of human and non-human primate brain tissue have the potential to reveal molecular pathways underlying remarkable specializations of the human brain. However, chimpanzee tissue is largely inaccessible during neocortical neurogenesi