Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Anne Drougard"'
Autor:
Anne Drougard, Eric H Ma, Vanessa Wegert, Ryan Sheldon, Ilaria Panzeri, Naman Vatsa, Stefanos Apostle, Luca Fagnocchi, Judith Schaf, Klaus Gossens, Josephine Völker, Shengru Pang, Anna Bremser, Erez Dror, Francesca Giacona, null Sagar, Michael X Henderson, Marco Prinz, Russell G Jones, J. Andrew Pospisilik
Chronic high-fat feeding triggers widespread metabolic dysfunction including obesity, insulin resistance, and diabetes. While these ultimate pathological states are relatively well understood, we have a limited understanding of how high-fat intake fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f396eac4320c577d48d58931e1d889c2
https://doi.org/10.1101/2023.04.03.535373
https://doi.org/10.1101/2023.04.03.535373
Autor:
Marc Schneeberger, Alicia G. Gómez-Valadés, Jordi Altirriba, David Sebastián, Sara Ramírez, Ainhoa Garcia, Yaiza Esteban, Anne Drougard, Albert Ferrés-Coy, Analía Bortolozzi, Pablo M. Garcia-Roves, John G. Jones, Bruno Manadas, Antonio Zorzano, Ramon Gomis, Marc Claret
Publikováno v:
Cell Reports, Vol 12, Iss 3, Pp 361-370 (2015)
Alterations in ER homeostasis have been implicated in the pathophysiology of obesity and type-2 diabetes (T2D). Acute ER stress induction in the hypothalamus produces glucose metabolism perturbations. However, the neurobiological basis linking hypoth
Externí odkaz:
https://doaj.org/article/cc60db24442144a08bb1ee9c99a52144
Autor:
Anne Abot, Coralie Fontaine, Mélissa Buscato, Romain Solinhac, Gilles Flouriot, Aurélie Fabre, Anne Drougard, Shyamala Rajan, Muriel Laine, Alain Milon, Isabelle Muller, Daniel Henrion, Marine Adlanmerini, Marie‐Cécile Valéra, Anne Gompel, Céline Gerard, Christel Péqueux, Mélanie Mestdagt, Isabelle Raymond‐Letron, Claude Knauf, François Ferriere, Philippe Valet, Pierre Gourdy, Benita S Katzenellenbogen, John A Katzenellenbogen, Françoise Lenfant, Geoffrey L Greene, Jean‐Michel Foidart, Jean‐François Arnal
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 10, Pp 1328-1346 (2014)
Abstract Estetrol (E4) is a natural estrogen with a long half‐life produced only by the human fetal liver during pregnancy. The crystal structures of the estrogen receptor α (ERα) ligand‐binding domain bound to 17β‐estradiol (E2) and E4 are
Externí odkaz:
https://doaj.org/article/f81d485b302d454596333e69beb5f6bc
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88325 (2014)
Eph receptors and their ephrin ligands play critical roles in the development of the nervous system, however, less is known about their functions in the adult brain. Here, we investigated the function of ephrinB1, an ephrinB family member that is mut
Externí odkaz:
https://doaj.org/article/359ded60ce91487a8fc6ca4ca6995b56
Autor:
Anne Drougard, Carrie V. Breton, Delphine Eberlé, Claude Knauf, Céline Guinez, Christine Laborie, Jean Lesage, Lucie Marousez, Didier Vieau, Simon Lecoutre
Publikováno v:
Journal of developmental origins of health and disease. 8(1)
Based on the Developmental Origin of Health and Disease concept, maternal undernutrition has been shown to sensitize adult offspring to metabolic pathologies such as obesity. Using a model of maternal 70% food restriction in pregnant female rats thro
Autor:
Joel Castro, Adrian Fournel, Sophie Le-Gonidec, Philippe Valet, Anne Drougard, Patrice D. Cani, Nicholas Cenac, Nathalie Vergnolle, Claude Knauf, Alysson Marlin, Stuart M. Brierley, André Colom, Thibaut Duparc, Perrine Rousset, Bernard Masri, Alexandre Lucas
Publikováno v:
Gut, Vol. 66, no. 2, p. 258-269 (2017)
Gut
Gut, BMJ Publishing Group, 2017, 66 (2), pp.258-269. ⟨10.1136/gutjnl-2015-310230⟩
Gut
Gut, BMJ Publishing Group, 2017, 66 (2), pp.258-269. ⟨10.1136/gutjnl-2015-310230⟩
ObjectiveThe gut–brain axis is considered as a major regulatory checkpoint in the control of glucose homeostasis. The detection of nutrients and/or hormones in the duodenum informs the hypothalamus of the host's nutritional state. This process may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9800fb736ca62c688d90a4b67b21178
https://hdl.handle.net/2078.1/167704
https://hdl.handle.net/2078.1/167704
Autor:
Anne Drougard, Claude Knauf, Jean Lesage, Alexandre Benani, Lionel Carneiro, Philippe Valet, Patrice D. Cani, Lucie Geurts, Anne-Catherine Prats, Didier Vieau, Audren Fournel, Xavier Brenachot, Thomas Cadoudal, Corinne Leloup, Luc Pénicaud, Alexandra Gouazé, Thibaut Duparc
Publikováno v:
Antioxidants and Redox Signaling
Antioxidants and Redox Signaling, Mary Ann Liebert, 2014, 20 (4), pp.557-573. ⟨10.1089/ars.2013.5182⟩
Antioxidants and Redox Signaling, 2014, 20 (4), pp.557-573. ⟨10.1089/ars.2013.5182⟩
Antioxidants and Redox Signaling, Mary Ann Liebert, 2014, 20 (4), pp.557-573. 〈10.1089/ars.2013.5182〉
Antioxidants and Redox Signaling, Mary Ann Liebert, 2014, 20 (4), pp.557-573. ⟨10.1089/ars.2013.5182⟩
Antioxidants and Redox Signaling, 2014, 20 (4), pp.557-573. ⟨10.1089/ars.2013.5182⟩
Antioxidants and Redox Signaling, Mary Ann Liebert, 2014, 20 (4), pp.557-573. 〈10.1089/ars.2013.5182〉
Aims: We have previously demonstrated that central apelin is implicated in the control of peripheral glycemia, and its action depends on nutritional (fast versus fed) and physiological (normal versus diabetic) states. An intracerebroventricular (icv)
Publikováno v:
Obésité. 8:136-140
Le cerveau, et plus particulierement l’hypothalamus, est le centre integrateur de nombreux signaux d’origines diverses impliques dans le controle de la satiete et du metabolisme energetique. Par l’intermediaire des systemes endocrinien et/ou ne
Autor:
Roberta Haddad-Tóvolli, Rosa Gasa, David A. Cano, Sara Cervantes, Andrés Vidal-Itriago, Iñigo Chivite, Alvaro Flores-Martínez, Anne Drougard, Luis Varela, Macarena Pozo, Ainhoa Garcia, Rubén Nogueiras, Sara Ramírez, Joan-Marc Servitja, Pablo M. Garcia-Roves, Alicia G. Gómez-Valadés, Pau Gama-Perez, Ramon Gomis, Marc Claret, Eduard Noguera, Tamas L. Horvath, Jordi Altirriba, Antonio Zorzano, Claude Knauf, Monica Imbernon, Marc Schneeberger
Publikováno v:
Cell metabolism. 25(6)
Proopiomelanocortin (POMC) neurons are critical sensors of nutrient availability implicated in energy balance and glucose metabolism control. However, the precise mechanisms underlying nutrient sensing in POMC neurons remain incompletely understood.
Autor:
Anne Drougard, Josef Priller, Steffen Jung, Moumita Datta, Dominic Mai, Anje Sporbert, Olaf Ronneberger, Gen Lin, Lars M. Steinmetz, Ori Staszewski, Dominic Grün, Jana Dautzenberg, Thomas Stempfl, Francisco Fernández-Klett, Anca Margineanu, J. Andrew Pospisilik, Sagar, Alberto Ardura-Fabregat, Marco Prinz, Tuan Leng Tay
Publikováno v:
Nature Neuroscience
Nature reviews / Neuroscience 20(6), 793-803 (2017). doi:10.1038/nn.4547
Nature reviews / Neuroscience 20(6), 793-803 (2017). doi:10.1038/nn.4547
Microglia constitute a highly specialized network of tissue-resident immune cells that is important for the control of tissue homeostasis and the resolution of diseases of the CNS. Little is known about how their spatial distribution is established a