Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Anne‐Marie Ray"'
Autor:
Pierre Fechter, Elisabete Cruz Da Silva, Marie-Cécile Mercier, Fanny Noulet, Nelly Etienne-Seloum, Dominique Guenot, Maxime Lehmann, Romain Vauchelles, Sophie Martin, Isabelle Lelong-Rebel, Anne-Marie Ray, Cendrine Seguin, Monique Dontenwill, Laurence Choulier
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 17, Iss , Pp 63-77 (2019)
Nucleic acid aptamers are often referred to as chemical antibodies. Because they possess several advantages, like their smaller size, temperature stability, ease of chemical modification, lack of immunogenicity and toxicity, and lower cost of product
Externí odkaz:
https://doaj.org/article/30a11660aa854869a73cb126015aaf9d
Autor:
Jared Sivinski, Andrew J. Ambrose, Iliya Panfilenko, Christopher J. Zerio, Jason M. Machulis, Niloufar Mollasalehi, Lynn K. Kaneko, Mckayla Stevens, Anne-Marie Ray, Yangshin Park, Chunxiang Wu, Quyen Q. Hoang, Steven M. Johnson, Eli Chapman
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
The GroES/GroEL chaperonin from E. coli
Externí odkaz:
https://doaj.org/article/ebd31eb709974744bdcf006fa3005b0d
Autor:
Li Wang, Priyanka Gajwani, Pallavi Chaturvedi, Zhigang Hong, Zijing Ye, Gregory J. Schwarz, Nicole M. Pohl-Avila, Anne-Marie Ray, Sarah Krantz, Peter T Toth, Deborah E. Leckband, Andrei Karginov, Jalees Rehman
Endothelial adherens junctions (AJs) are critical for the regulation of vascular barrier integrity and undergo dis-assembly during inflammatory injury, thus causing vascular leakiness. AJ re-assembly is thus necessary for restoration of the endotheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bf4c77760cee74e7d7a620522675a4f
https://doi.org/10.1101/2022.11.11.516184
https://doi.org/10.1101/2022.11.11.516184
Autor:
Siddhi Chitre, Anne-Marie Ray, Mckayla Stevens, Emma H. Doud, Hope Liechty, Alex Washburn, Katelyn Tepper, Jared Sivinski, Heather M. O'Hagan, Millie M. Georgiadis, Eli Chapman, Steven M. Johnson
Publikováno v:
Bioorganicmedicinal chemistry. 75
While many studies have established the importance of protein homeostasis in tumor progression, little effort has been made to examine the therapeutic potential of targeting the HSP60 chaperonin system. In healthy cells, HSP60 is localized to the mit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d64170a8200acc1dcd918dae6bc00628
https://pubmed.ncbi.nlm.nih.gov/36356534
https://pubmed.ncbi.nlm.nih.gov/36356534
Autor:
Jared Sivinski, Duc Ngo, Christopher J. Zerio, Andrew J. Ambrose, Edmond R. Watson, Lynn K. Kaneko, Marius M. Kostelic, Mckayla Stevens, Anne‐Marie Ray, Yangshin Park, Chunxiang Wu, Michael T. Marty, Quyen Q. Hoang, Donna D. Zhang, Gabriel C. Lander, Steven M. Johnson, Eli Chapman
Publikováno v:
FASEB J
GroES/GroEL is the only bacterial chaperone essential under all conditions, making it a potential antibiotic target. Rationally targeting ESKAPE GroES/GroEL as an antibiotic strategy necessitates studying their structure and function. Herein, we outl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80fdbcdf0cdf11d1c334ee2fd902172a
https://doi.org/10.1096/fj.202101708rr
https://doi.org/10.1096/fj.202101708rr
Autor:
Anne-Marie Ray, Tanya Parish, Yulia Ovechkina, Jared Sivinski, Steven M. Johnson, Siddhi Chitre, Yangshin Park, Eli Chapman, Mckayla Stevens, James Johnson, Quyen Q. Hoang, Alex Washburn, Sanofar Abdeen
Publikováno v:
Bioorg Med Chem Lett
Current treatments for Mycobacterium tuberculosis infections require long and complicated regimens that can lead to patient non-compliance, increasing incidences of antibiotic-resistant strains, and lack of efficacy against latent stages of disease.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::000bc8e2afa8fcd9aff724ab32e262c4
https://doi.org/10.1016/j.bmcl.2019.04.034
https://doi.org/10.1016/j.bmcl.2019.04.034
Autor:
Sanofar Abdeen, Nilshad Salim, Jared Sivinski, Mckayla Stevens, Siddhi Chitre, Eli Chapman, Anne-Marie Ray, Quyen Q. Hoang, Steven M. Johnson, Alex Washburn, Yangshin Park
Publikováno v:
Bioorg Med Chem Lett
All living organisms contain a unique class of molecular chaperones called 60 kDa heat shock proteins (HSP60 – also known as GroEL in bacteria). While some organisms contain more than one HSP60 or GroEL isoform, at least one isoform has always prov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbf0c41ab3fe19e9b67203627d87ce61
https://doi.org/10.1016/j.bmcl.2019.02.028
https://doi.org/10.1016/j.bmcl.2019.02.028
Autor:
Maxime Lehmann, Pierre Fechter, Marie-Cécile Mercier, Sophie Martin, Dominique Guenot, Nelly Etienne-Seloum, Laurence Choulier, Elisabete Cruz Da Silva, Fanny Noulet, Romain Vauchelles, Isabelle Lelong-Rebel, Monique Dontenwill, Anne-Marie Ray, Cendrine Seguin
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy-Nucleic Acids
Molecular Therapy-Nucleic Acids, Elsevier, 2019, 17, pp.63-77. ⟨10.1016/j.omtn.2019.05.006⟩
Molecular Therapy: Nucleic Acids, Vol 17, Iss, Pp 63-77 (2019)
Molecular Therapy-Nucleic Acids, Nature Publishing Group, 2019, 17, pp.63-77. ⟨10.1016/j.omtn.2019.05.006⟩
Molecular Therapy-Nucleic Acids
Molecular Therapy-Nucleic Acids, Elsevier, 2019, 17, pp.63-77. ⟨10.1016/j.omtn.2019.05.006⟩
Molecular Therapy: Nucleic Acids, Vol 17, Iss, Pp 63-77 (2019)
Molecular Therapy-Nucleic Acids, Nature Publishing Group, 2019, 17, pp.63-77. ⟨10.1016/j.omtn.2019.05.006⟩
Nucleic acid aptamers are often referred to as chemical antibodies. Because they possess several advantages, like their smaller size, temperature stability, ease of chemical modification, lack of immunogenicity and toxicity, and lower cost of product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c22813bfe0aeb50025079672ce40b48a
http://europepmc.org/articles/PMC6586995
http://europepmc.org/articles/PMC6586995
Autor:
Iliya Panfilenko, Christopher J. Zerio, Jason M. Machulis, Yangshin Park, Eli Chapman, Chun-Xiang Wu, Andrew J. Ambrose, Mckayla Stevens, Lynn Kaneko, Steven M. Johnson, Niloufar Mollasalehi, Jared Sivinski, Anne-Marie Ray, Quyen Q. Hoang
Publikováno v:
mBio
mBio, Vol 12, Iss 1 (2021)
mBio, Vol 12, Iss 1 (2021)
The GroES/GroEL chaperonin from E. coli has long served as the model system for other chaperonins. This assumption seemed valid because of the high conservation between the chaperonins.
As the GroES/GroEL chaperonin system is the only bacterial
As the GroES/GroEL chaperonin system is the only bacterial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75306fc2ba6b09d71878d59f9c62a71b
https://pubmed.ncbi.nlm.nih.gov/33436430
https://pubmed.ncbi.nlm.nih.gov/33436430
Autor:
Siddhi Chitre, Mckayla Stevens, Eli Chapman, Jared Sivinski, Yangshin Park, Anne-Marie Ray, Quyen Q. Hoang, Alex Washburn, Steven M. Johnson, Chris Howe
Publikováno v:
Bioorg Med Chem
In two previous studies, we identified compound 1 as a moderate GroEL/ES inhibitor with weak to moderate antibacterial activity against Gram-positive and Gram-negative bacteria including Bacillus subtilis, methicillin-resistant Staphylococcus aureus,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a9b20c557c56eae7acde5fd5c05616
https://europepmc.org/articles/PMC7914298/
https://europepmc.org/articles/PMC7914298/