Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Anne‐Karina T. Perl"'
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 7, Pp 1021-1032 (2021)
Abstract Developing, regenerating, and repairing a lung all require interstitial resident fibroblasts (iReFs) to direct the behavior of the epithelial stem cell niche. During lung development, distal lung fibroblasts, in the form of matrix‐, myo‐
Externí odkaz:
https://doaj.org/article/7110469d517645c5b39f5f3eb763f297
Autor:
Matthew R. Riccetti, Mereena George Ushakumary, Marion Waltamath, Jenna Green, John Snowball, Sydney E. Dautel, Mehari Endale, Bonny Lami, Jason Woods, Shawn K. Ahlfeld, Anne-Karina T. Perl
Publikováno v:
JCI Insight, Vol 7, Iss 5 (2022)
Infants born prematurely worldwide have up to a 50% chance of developing bronchopulmonary dysplasia (BPD), a clinical morbidity characterized by dysregulated lung alveolarization and microvascular development. It is known that PDGFR alpha–positive
Externí odkaz:
https://doaj.org/article/b64d940fd4a04216a9cec3d2b72e8c02
Autor:
Nikeya Tisdale-Macioce, Jenna Green, Anne-Karina T. Perl, Alan Ashbaugh, Nathan P. Wiederhold, Thomas F. Patterson, Melanie T. Cushion
Publikováno v:
Frontiers in Fungal Biology, Vol 2 (2021)
Pneumocystis species (spp.) are host-obligate fungal parasites that colonize and propagate almost exclusively in the alveolar lumen within the lungs of mammals where they can cause a lethal pneumonia. The emergence of this pneumonia in non-HIV infect
Externí odkaz:
https://doaj.org/article/218691d2b7b74bd298aeba6d175c3012
Autor:
Sneha Sitaraman, Emily P. Martin, Cheng-Lun Na, Shuyang Zhao, Jenna Green, Hitesh Deshmukh, Anne-Karina T. Perl, James P. Bridges, Yan Xu, Timothy E. Weaver
Publikováno v:
JCI Insight, Vol 6, Iss 14 (2021)
Mutations in the gene SFTPC, encoding surfactant protein C (SP-C), are associated with interstitial lung disease in children and adults. To assess the natural history of disease, we knocked in a familial, disease-associated SFTPC mutation, L188Q (L18
Externí odkaz:
https://doaj.org/article/155f93a81492430d8e13d1f5851c0f12
Autor:
Seagal Teitz-Tennenbaum, Steven P. Viglianti, Ahmad Jomma, Quentin Palone, Halia Andrews, Kayla N. Selbmann, Shayanki Lahiri, Natalia Subbotina, Natalie Walker, Anne-Karina T. Perl, Vibha N. Lama, Thomas H. Sisson, John J. Osterholzer
Publikováno v:
Am J Pathol
Histopathologic evidence of deployment-related constrictive bronchiolitis (DRCB) has been identified in soldiers deployed to Southwest Asia. While inhalational injury to the airway epithelium is suspected, relatively little is known about the pathoge
Autor:
Jillian J Spinney, Anne-Karina T. Perl, Katharine E. Black, Lida P. Hariri, Marion Waltamath, Jenna Green, John Snowball, Jason J. Gokey, Yan Xu
Publikováno v:
Thorax
ObjectivesIdiopathic pulmonary fibrosis (IPF) primarily affects the aged population and is characterised by failure of alveolar regeneration, leading to loss of alveolar type 1 (AT1) cells. Aged mouse models of lung repair have demonstrated that rege
Autor:
Minzhe Guo, Matt Riccetti, Erik Zhang, Andrew S. Potter, Francis X. McCormack, Krinio Giannikou, S. Steven Potter, Anne-Karina T. Perl, Stephen R. Hammes, Kathryn A. Wikenheiser-Brokamp, Jane J. Yu, Sue Sherman, Yan Xu, Mike Adam, David J. Kwiatkowski, Jeffrey A. Whitsett, Elizabeth J. Kopras, Parvathi Sudha
Publikováno v:
American Journal of Respiratory and Critical Care Medicine
Rationale: Lymphangioleiomyomatosis (LAM) is a metastatic neoplasm of reproductive-age women associated with mutations in tuberous sclerosis complex genes. LAM causes cystic remodeling of the lung ...
Autor:
Shuyang Zhao, James P. Bridges, Emily P. Martin, Anne-Karina T. Perl, Cheng-Lun Na, Timothy E. Weaver, Hitesh Deshmukh, Sneha Sitaraman, Yan Xu, Jenna Green
Publikováno v:
JCI Insight
Mutations in the gene SFTPC, encoding surfactant protein C (SP-C), are associated with interstitial lung disease in children and adults. To assess the natural history of disease, we knocked in a familial, disease-associated SFTPC mutation, L188Q (L18
Autor:
Matthew R. Riccetti, Mereena George Ushakumary, Marion Waltamath, Jenna Green, John Snowball, Sydney E. Dautel, Mehari Endale, Bonny Lami, Jason Woods, Shawn K. Ahlfeld, Anne-Karina T. Perl
Publikováno v:
JCI insight. 7(5)
Infants born prematurely worldwide have up to a 50% chance of developing bronchopulmonary dysplasia (BPD), a clinical morbidity characterized by dysregulated lung alveolarization and microvascular development. It is known that PDGFR alpha-positive (P
Publikováno v:
Matrix Biol
During lung development, the mesenchyme and epithelium are dependent on each other for instructive morphogenic cues that direct proliferation, cellular differentiation and organogenesis. Specification of epithelial and mesenchymal cell lineages occur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403d83b9143ff06402a761b21d79e00e
https://europepmc.org/articles/PMC7434667/
https://europepmc.org/articles/PMC7434667/