Zobrazeno 1 - 10
of 165
pro vyhledávání: '"Anne‐Claire Toffart"'
Autor:
Anne Mc Leer, PhD, Julie Mondet, PharmD, PhD, Nelly Magnat, MSc, Mailys Mersch, MSc, Diane Giovannini, MD, Camille Emprou, MD, Anne-Claire Toffart, MD, PhD, Nathalie Sturm, MD, PhD, Sylvie Lantuéjoul, MD, PhD, David Benito, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 12, Pp 100714- (2024)
Introduction: RET rearrangements occur in 1% to 2% NSCLCs. Since no clinically validated RET antibody is currently available, fluorescence in situ hybridization (FISH) is often used as a screening tool to identify patients likely to benefit from RET-
Externí odkaz:
https://doaj.org/article/4980913fe42d45de90e92091df11b88f
Autor:
Jacques Gaillat, Elodie Sellier, Patrice Francois, Magali Bouisse, Xavier Courtois, José Labarère, Ethan A Halm, Anne-Claire Toffart, Sophie Blaise, Carole Schwebel, Anne Danjou, Bastien Boussat
Publikováno v:
BMJ Open Respiratory Research, Vol 11, Iss 1 (2024)
Objective Five definitions of clinical instability have been published to assess the appropriateness and safety of discharging patients hospitalised for pneumonia. This study aimed to quantify the level of agreement between these definitions and esti
Externí odkaz:
https://doaj.org/article/a6add5e9719e44ce9eb9865534b7d781
Autor:
Francesca Lucibello, MD, Valérie Gounant, MD, PhD, Mihaela Aldea, MD, PhD, Michaël Duruisseaux, MD, PhD, Maurice Perol, MD, Christos Chouaid, MD, Jaafar Bennouna, MD, PhD, Vincent Fallet, MD, Aldo Renault, MD, Florian Guisier, MD, PhD, Etienne Giroux-Leprieur, MD, PhD, Marie Wislez, MD, PhD, Anne-Claire Toffart, MD, PhD, Julien Mazieres, MD, PhD, Clémence Basse, MD, PhD, Nadia Hegarat, PhD, Matthieu Carton, MD, Nicolas Girard, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 6, Iss 1, Pp 100743- (2025)
Introduction: Pralsetinib is a RET inhibitor found to have antitumor activity in advanced, metastatic, RET fusion-positive NSCLC. Objective: To assess real-world efficacy of pralsetinib and treatment sequences in patients with RET fusion-positive NSC
Externí odkaz:
https://doaj.org/article/0c41f917b5ca448d96c9f58872859bd4
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
The KRAS protein, a product of the KRAS gene (V-ki-ras2 Kirsten rat sarcoma viral oncogene homolog), functions as a small GTPase that alternates between an active GTP-bound state (KRAS(ON)) and an inactive GDP-bound state (KRAS(OFF)). The KRASG12C mu
Externí odkaz:
https://doaj.org/article/1055145bf0da40a7975e74cc2ae8ad35
Autor:
Marco Tagliamento, Marie Morfouace, Charalambos Loizides, Julio Oliveira, Laurent Greillier, Judith Raimbourg, Anne-Claire Toffart, Thierry Chatellier, Nicolas Cloarec, Ivana Sullivan, Birute Brasiuniene, Michael Duruisseaux, Kersti Oselin, Marie-Sophie Robert, Carolina Fernandes, Arnaud Poncin, Jean-Yves Blay, Benjamin Besse, Nicolas Girard
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-5 (2024)
Abstract Arcagen (NCT02834884) is a European prospective study aiming at defining the molecular landscape of rare cancers for treatment guidance. We present data from the cohort of rare thoracic tumors. Patients with advanced pleural mesothelioma (PM
Externí odkaz:
https://doaj.org/article/a551359448e24d6eb9add62a36f641d1
Autor:
Hélène Pluchart, Sébastien Bailly, Sébastien Chanoine, Denis Moro-Sibilot, Pierrick Bedouch, Anne-Claire Toffart
Publikováno v:
BMC Medical Research Methodology, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background The comorbidity burden has a negative impact on lung-cancer survival. Several comorbidity scores have been described and are currently used. The current challenge is to select the comorbidity score that best reflects their impact
Externí odkaz:
https://doaj.org/article/742ab98675b747b4b0dc6d7ad52cbbb2
Autor:
Hélène Pluchart, Sébastien Chanoine, Denis Moro-Sibilot, Christos Chouaid, Gil Frey, Julie Villa, Bruno Degano, Matteo Giaj Levra, Pierrick Bedouch, Anne-Claire Toffart
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Most patients with lung cancer are smokers and are of advanced age. They are therefore at high risk of having age- and lifestyle-related comorbidities. These comorbidities are subject to treatment or even polypharmacy. There is growing evidence of a
Externí odkaz:
https://doaj.org/article/bb23e6f3c8cf4b5998347bf1f9f10caa
Autor:
Hélène Pluchart, Sébastien Bailly, Sébastien Chanoine, Denis Moro-Sibilot, Pierrick Bedouch, Anne-Claire Toffart
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-6 (2023)
Abstract Background Although polypharmacy has been described among cancer patients, very few studies have focused on those with lung cancer. We aimed to assess whether polypharmacy and comorbidity have an impact on systemic parenteral treatment admin
Externí odkaz:
https://doaj.org/article/e438e153dfc64a81a2c9b284ee839a0f
Autor:
Anne-Claire Toffart, Anne-Pascale Meert, Florent Wallet, Aude Gibelin, Olivier Guisset, Frédéric Gonzalez, Amélie Seguin, Achille Kouatchet, Myriam Delaunay, Didier Debieuvre, Boris Duchemann, Gaëlle Rousseau-Bussac, Martine Nyunga, David Grimaldi, Albrice Levrat, Elie Azoulay, Virginie Lemiale
Publikováno v:
Annals of Intensive Care, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Background Immune checkpoint inhibitors (ICI) have revolutionized the management of cancer. They can induce immune-related adverse events (irAE) leading to intensive care unit (ICU) admission. We aimed to describe irAEs for ICU admissions in
Externí odkaz:
https://doaj.org/article/959ab086f8e742cf93c8fac187f619e3
Autor:
Anne‐Sophie Hatat, Clara Benoit‐Pilven, Amélie Pucciarelli, Florence deFraipont, Lucie Lamothe, Pascal Perron, Amandine Rey, Matteo Giaj Levra, Anne‐Claire Toffart, Didier Auboeuf, Beatrice Eymin, Sylvie Gazzeri
Publikováno v:
Molecular Oncology, Vol 16, Iss 19, Pp 3490-3508 (2022)
Despite the initial efficacy of using tyrosine kinase inhibitors of epidermal growth factor receptors (EGFR‐TKIs) for treating patients with non‐small cell lung cancer (NSCLC), resistance inevitably develops. Recent studies highlight a link betwe
Externí odkaz:
https://doaj.org/article/b72c5db1e289451ca303938baa5d229b