Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Anne, Wojtusciszyn"'
Autor:
Matthieu Raoux, Sandrine Lablanche, Manon Jaffredo, Antoine Pirog, Pierre-Yves Benhamou, Fanny Lebreton, Anne Wojtusciszyn, Domenico Bosco, Thierry Berney, Sylvie Renaud, Jochen Lang, Bogdan Catargi
Publikováno v:
Transplant International, Vol 36 (2023)
Islet transplantation improves metabolic control in patients with unstable type 1 diabetes. Clinical outcomes have been improving over the last decade, and the widely used beta-score allows the evaluation of transplantation results. However, predicti
Externí odkaz:
https://doaj.org/article/e05f75d0958c450d8a8ba1f5a17427ac
Autor:
Marta Fontcuberta-PiSunyer, Ainhoa García-Alamán, Èlia Prades, Noèlia Téllez, Hugo Alves-Figueiredo, Mireia Ramos-Rodríguez, Carlos Enrich, Rebeca Fernandez-Ruiz, Sara Cervantes, Laura Clua, Javier Ramón-Azcón, Christophe Broca, Anne Wojtusciszyn, Nuria Montserrat, Lorenzo Pasquali, Anna Novials, Joan-Marc Servitja, Josep Vidal, Ramon Gomis, Rosa Gasa
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Human foreskin fibroblasts are directly reprogrammed into insulin-producing cells using 5 pancreatic transcription factors, without pluripotency induction.
Externí odkaz:
https://doaj.org/article/29d2817f5dfe44d989d5e0fd8d306fda
Autor:
Matthew R. Brown, Damien Laouteouet, Morgane Delobel, Orianne Villard, Christophe Broca, Gyslaine Bertrand, Anne Wojtusciszyn, Stéphane Dalle, Magalie A. Ravier, Aleksey V. Matveyenko, Safia Costes
Publikováno v:
Cell Death and Disease, Vol 13, Iss 4, Pp 1-12 (2022)
Abstract Pancreatic β-cell failure in type 2 diabetes mellitus (T2DM) is associated with impaired regulation of autophagy which controls β-cell development, function, and survival through clearance of misfolded proteins and damaged organelles. Howe
Externí odkaz:
https://doaj.org/article/b8f90d9713164bc79d87bd9e85ebe040
Autor:
Matthias Hepprich, Jonathan M. Mudry, Claudia Gregoriano, Francois R. Jornayvaz, Sebastian Carballo, Anne Wojtusciszyn, Pierre-Alexandre Bart, Jean-Daniel Chiche, Stefan Fischli, Thomas Baumgartner, Claudia Cavelti-Weder, Dominique L. Braun, Huldrych F. Günthard, Felix Beuschlein, Anna Conen, Emily West, Egon Isenring, Stefan Zechmann, Gabriela Bucklar, Yoann Aubry, Ludovic Dey, Beat Müller, Patrick Hunziker, Philipp Schütz, Marco Cattaneo, Marc Y. Donath
Publikováno v:
EClinicalMedicine, Vol 53, Iss , Pp 101649- (2022)
Summary: Background: Patients with type 2 diabetes and obesity have chronic activation of the innate immune system possibly contributing to the higher risk of hyperinflammatory response to SARS-CoV2 and severe COVID-19 observed in this population. We
Externí odkaz:
https://doaj.org/article/197006e344dd4ae1bdcf99258310af46
Precision medicine in the era of artificial intelligence: implications in chronic disease management
Autor:
Murugan Subramanian, Anne Wojtusciszyn, Lucie Favre, Sabri Boughorbel, Jingxuan Shan, Khaled B. Letaief, Nelly Pitteloud, Lotfi Chouchane
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-12 (2020)
Abstract Aberrant metabolism is the root cause of several serious health issues, creating a huge burden to health and leading to diminished life expectancy. A dysregulated metabolism induces the secretion of several molecules which in turn trigger th
Externí odkaz:
https://doaj.org/article/7474f0910e8b4a6cb0f759f4b08eb8a3
Autor:
Rebeca Fernandez-Ruiz, Ainhoa García-Alamán, Yaiza Esteban, Joan Mir-Coll, Berta Serra-Navarro, Marta Fontcuberta-PiSunyer, Christophe Broca, Mathieu Armanet, Anne Wojtusciszyn, Vardit Kram, Marian F. Young, Josep Vidal, Ramon Gomis, Rosa Gasa
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The proliferation of pancreatic beta cells decreases with age, partly due to systemic changes. Here the authors identify Wisp1 as a circulating factor enriched in young serum that induces adult beta cell proliferation, supporting the idea that young
Externí odkaz:
https://doaj.org/article/75526fb6644249f68e8b4986865a300c
Autor:
Orianne Villard, Mathieu Armanet, Guilhem Couderc, Claire Bony, Jerome Moreaux, Daniele Noël, John DeVos, Bernard Klein, Jean-Luc Veyrune, Anne Wojtusciszyn
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-13 (2020)
Abstract Background Mesenchymal stromal cells (MSCs) represent an interesting tool to improve pancreatic islet transplantation. They have immunomodulatory properties and secrete supportive proteins. However, the functional properties of MSCs vary acc
Externí odkaz:
https://doaj.org/article/7a1ad9f4af16455fb369a2c6553641fb
Autor:
Heeyoung Chae, Robert Augustin, Eva Gatineau, Eric Mayoux, Mohammed Bensellam, Nancy Antoine, Firas Khattab, Bao-Khanh Lai, Davide Brusa, Birgit Stierstorfer, Holger Klein, Bilal Singh, Lucie Ruiz, Michael Pieper, Michael Mark, Pedro L. Herrera, Fiona M. Gribble, Frank Reimann, Anne Wojtusciszyn, Christophe Broca, Nano Rita, Lorenzo Piemonti, Patrick Gilon
Publikováno v:
Molecular Metabolism, Vol 42, Iss , Pp 101071- (2020)
Objective: Sodium-glucose cotransporter 2 (SGLT2) inhibitors (SGLT2i), or gliflozins, are anti-diabetic drugs that lower glycemia by promoting glucosuria, but they also stimulate endogenous glucose and ketone body production. The likely causes of the
Externí odkaz:
https://doaj.org/article/21bfada24dc04976b5da4c463b456525
Autor:
Damaris Cleary, Sophia Hannou, Linda Quiaios, Pierre Monney, Roger Hullin, Anne Wojtusciszyn, Christophe Büla, Sylvain Nguyen
Publikováno v:
Revue Médicale Suisse. 18:2057-2062
Publikováno v:
Revue Médicale Suisse. 18:1116-1122