Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Anne, Wierinckx"'
Autor:
Rudy Gadet, Lea Jabbour, Trang Thi Minh Nguyen, Olivier Lohez, Ivan Mikaelian, Philippe Gonzalo, Tomas Luyten, Mounira Chalabi-Dchar, Anne Wierinckx, Olivier Marcillat, Geert Bultynck, Ruth Rimokh, Nikolay Popgeorgiev, Germain Gillet
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Apoptosis plays a role in cell homeostasis in both normal development and disease. Bcl-xL, a member of the Bcl-2 family of proteins, regulates the intrinsic mitochondrial pathway of apoptosis. It is overexpressed in several cancers. Bcl-xL h
Externí odkaz:
https://doaj.org/article/34c348a12fb44ef2916bea077f155ce7
Autor:
Hélène Lasolle, Mad-Hélénie Elsensohn, Anne Wierinckx, Eudeline Alix, Clément Bonnefille, Alexandre Vasiljevic, Christine Cortet, Bénédicte Decoudier, Nathalie Sturm, Stephan Gaillard, Amandine Ferrière, Pascal Roy, Emmanuel Jouanneau, Philippe Bertolino, Claire Bardel, Damien Sanlaville, Gérald Raverot
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-14 (2020)
Abstract The purpose of this study was to analyze the impact of copy number variations (CNV) on sporadic pituitary neuroendocrine tumors (PitNETs) prognosis, to identify specific prognosis markers according to the known clinico-pathological classific
Externí odkaz:
https://doaj.org/article/bad74d408c3644daa9aeac245f2ab195
Autor:
Aurélie Bellanger, Diep T. Le, Julie Vendrell, Anne Wierinckx, Lőrinc S. Pongor, Jérôme Solassol, Joël Lachuer, Philippe Clezardin, Balázs Győrffy, Pascale A. Cohen
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Oncogene alternative splicing events can create distinct functional transcripts that offer new candidate prognostic biomarkers for breast cancer. ZNF217 is a well-established oncogene but its exon 4-skipping isoform (ZNF217-ΔE4) has never been inves
Externí odkaz:
https://doaj.org/article/447ddc6507a346b49865519fc7d3eb12
Autor:
Caterina F. Donini, Myriam El Helou, Anne Wierinckx, Balázs Győrffy, Sophie Aires, Aurélie Escande, Séverine Croze, Philippe Clezardin, Joël Lachuer, Mona Diab-Assaf, Sandra E. Ghayad, Béatrice Fervers, Vincent Cavaillès, Véronique Maguer-Satta, Pascale A. Cohen
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
It is of utmost importance to decipher the role of chronic exposure to low doses of environmental carcinogens on breast cancer progression. The early-transformed triple-negative human mammary MCF10AT1 cells were chronically (60 days) exposed to low d
Externí odkaz:
https://doaj.org/article/9deef468b8a74ab58e8ea72c1647ba1c
Autor:
Charles Dumontet, Eva-Laure Matera, Christian Klein, Lars Petter Jordheim, Elsa Kress, Fabian Birzele, Aurore Bourguignon, Nolan Talhi, Anne Tourette, Kamel Chettab, Doriane Mathé, Anne Wierinckx, Pierre-Antoine Choffour, Chloé Grasselly, Morgane Denis
Supplementary Data from In Vivo Syngeneic Tumor Models with Acquired Resistance to Anti–PD-1/PD-L1 Therapies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c1d470b26a064a247545c2063ac39c1
https://doi.org/10.1158/2326-6066.22545206.v1
https://doi.org/10.1158/2326-6066.22545206.v1
Autor:
Charles Dumontet, Eva-Laure Matera, Christian Klein, Lars Petter Jordheim, Elsa Kress, Fabian Birzele, Aurore Bourguignon, Nolan Talhi, Anne Tourette, Kamel Chettab, Doriane Mathé, Anne Wierinckx, Pierre-Antoine Choffour, Chloé Grasselly, Morgane Denis
Antibodies targeting PD-1 and PD-L1 have produced durable responses in a subset of patients with cancer. However, a majority of these patients will ultimately relapse due to acquired resistance. To explore the underlying mechanisms of this secondary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f888b755b1943311e115d6c0ed7178
https://doi.org/10.1158/2326-6066.c.6550883.v1
https://doi.org/10.1158/2326-6066.c.6550883.v1
Autor:
Guillaume Collin, Jean-Philippe Foy, Nicolas Aznar, Nicolas Rama, Anne Wierinckx, Pierre Saintigny, Alain Puisieux, Stéphane Ansieau
Publikováno v:
Cancers
Volume 15
Issue 3
Pages: 973
Volume 15
Issue 3
Pages: 973
Reactive oxygen species (ROS) are considered to be the main drivers of inflammatory bowel disease. We investigated whether this permanent insult compels intestinal stem cells to develop strategies to dampen the deleterious effects of ROS. As an adver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0aceda5378cfff025e84b731fac63c
Autor:
Anne Wierinckx, Etienne Delgrange, Philippe Bertolino, Patrick François, Philippe Chanson, Emmanuel Jouanneau, Joël Lachuer, Jacqueline Trouillas, Gérald Raverot
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Sex-related differences have been reported in various cancers, in particular men with lactotroph tumors have a worse prognosis than women. While the underlying mechanism of this sexual dimorphism remains unclear, it has been suggested that a lower es
Externí odkaz:
https://doaj.org/article/718ba2bd85d14e10847af69d01b2d8f3
Autor:
Morgane Denis, Chloé Grasselly, Pierre-Antoine Choffour, Anne Wierinckx, Doriane Mathé, Kamel Chettab, Anne Tourette, Nolan Talhi, Fabian Birzele, Elsa Kress, Lars Petter Jordheim, Christian Klein, Eva-Laure Matera, Charles Dumontet
Publikováno v:
Cancer Research. 82:4200-4200
The underlying mechanisms of acquired resistance to the immune checkpoint inhibitory (ICI) PD-1 and PD-L1 antibodies remain largely unknown and need to be further explored. In this study, we established and analyzed robust ICI resistance in in vivo m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c48ce0db5b23c3e7f5b0460bce21f0c5
https://doi.org/10.1158/1538-7445.am2022-4200
https://doi.org/10.1158/1538-7445.am2022-4200
Autor:
Baptiste Gras, Laurent Jacqueroud, Anne Wierinckx, Christelle Lamblot, Frédérique Fauvet, Joël Lachuer, Alain Puisieux, Stéphane Ansieau
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92254 (2014)
By fostering cell commitment to the epithelial-to-mesenchymal transition (EMT), SNAIL proteins endow cells with motility, thereby favoring the metastatic spread of tumor cells. Whether the phenotypic change additionally facilitates tumor initiation h
Externí odkaz:
https://doaj.org/article/1632780bb24d49aaacefdffef0c2f107