Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Anne, Stürzebecher"'
Autor:
Michael Deters, Anne Stürzebecher
Publikováno v:
Deutsches Ärzteblatt international.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ce2fd0d73aefe77c26333575f24f6e3
https://doi.org/10.3238/arztebl.m2022.0185
https://doi.org/10.3238/arztebl.m2022.0185
Autor:
Mandy Gollmann, Gesine Liebetrau, Dagmar Prasa, Michael Deters, Anne Stürzebecher, S. Just, Germaine Frimlova
Publikováno v:
Das Gesundheitswesen. 81:397-404
Zusammenfassung Ziel der Studie Substanzmissbrauch war in den letzten Jahren starken Veränderungen unterworfen und ist eine große Herausforderung für die Klinische Toxikologie. Deswegen wurden Substanzmissbrauchsfälle der letzten 15 Jahre im Einz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d94705a98f96a65892430ffd64ff8a07
https://doi.org/10.1055/a-0592-6674
https://doi.org/10.1055/a-0592-6674
Autor:
Mandy, Gollmann, Germaine, Frimlova, Simone, Just, Gesine, Liebetrau, Dagmar, Prasa, Anne, Stürzebecher, Michael, Deters
Publikováno v:
Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)). 81(5)
Poisoning due to substance abuse has changed significantly during the last few years. Therefore, developments of substance abuse reported to the Poisons Information Centre Erfurt were investigated and compared to other circumstances of human exposure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::44fe5398de82ba91a62c39bfadd0083d
https://pubmed.ncbi.nlm.nih.gov/29719914
https://pubmed.ncbi.nlm.nih.gov/29719914
Autor:
Andrea Schweinitz, Rainer Friedrich, Manuel E. Than, Daniel Dönnecke, Anne Stürzebecher, Jörg Stürzebecher, Wolfram Bode, Friedemann Müller, Torsten Steinmetzer, Oliver Schuster, Peter Steinmetzer, Kerstin Uhland
Publikováno v:
Journal of Medicinal Chemistry. 49:4116-4126
Matriptase is an epithelium-derived type II transmembrane serine protease and has been implicated in the activation of substrates such as pro-HGF/SF and pro-uPA, which are likely involved in tumor progression and metastasis. Through screening, we hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23fe21184a1eea6aaa942638cbf1bde0
https://doi.org/10.1021/jm051272l
https://doi.org/10.1021/jm051272l
Autor:
Andrea Schweinitz, Peter Steinmetzer, Joscha Kotthaus, Bernd Clement, Torsten Steinmetzer, Jörg Stürzebecher, Oliver Schuster, Daniel Dönnecke, Uta Stürzebecher, Anne Stürzebecher
Publikováno v:
ChemMedChem. 2(7)
A series of highly potent substrate-analogue factor Xa inhibitors containing D-homophenylalanine analogues as the P3 residue has been identified by systematic optimization of a previously described inhibitor structure. An initial lead, benzylsulfonyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::251730145234e89a0ace116a29f8a0eb
https://pubmed.ncbi.nlm.nih.gov/17541992
https://pubmed.ncbi.nlm.nih.gov/17541992
Autor:
Daniel Dönnecke, Torsten Steinmetzer, Maj Schuster, Anne Stürzebecher, Uta Stürzebecher, Silke Nicklisch, Andrea Schweinitz, Peter Steinmetzer, Jörg Stürzebecher
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(12)
Highly potent and selective substrate analogue factor Xa inhibitors were obtained by incorporation of non-basic or modestly basic P1 residues known from the development of thrombin inhibitors. The modification of the P2 and P3 amino acids strongly in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::912b9fa751f6838214066b0d23da00ab
https://pubmed.ncbi.nlm.nih.gov/17462889
https://pubmed.ncbi.nlm.nih.gov/17462889
New substrate analogue inhibitors of factor Xa containing 4-amidinobenzylamide as P1 residue: part 1
Autor:
Andrea Schweinitz, Oliver Schuster, Torsten Steinmetzer, Anne Stürzebecher, Uta Stürzebecher, Jörg Stürzebecher
Publikováno v:
Medicinal chemistry (Shariqah (United Arab Emirates)). 2(4)
The trypsin-like serine protease factor Xa (fXa) is located at the convergence point of the intrinsic and extrinsic coagulation cascade, and therefore has emerged as an attractive target for the design of novel anticoagulants. During the development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f6d9639ec5595b57c8a5d10e48c771d
https://pubmed.ncbi.nlm.nih.gov/16848746
https://pubmed.ncbi.nlm.nih.gov/16848746
Autor:
Torsten Steinmetzer, Maria C Stella, Kerstin Uhland, Stefan Thiel, Andrea Schweinitz, Jörg Stürzebecher, Anne Stürzebecher, Diana Förbs
Publikováno v:
International Journal of Oncology.
Matriptase, also known as membrane-type-serine-protease 1 (MT-SP 1), is a type II transmembrane serine protease involved in the activation of the precursor form of hepatocyte growth factor/scatter factor (pro-HGF/SF). Since HGF/SF is a well-known ext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b6c6304545dd6b687d24fb1ca1d11b
https://doi.org/10.3892/ijo.27.4.1061
https://doi.org/10.3892/ijo.27.4.1061
Autor:
Andreas Geissler, Anne Stürzebecher, Torsten Steinmetzer, Helmut Giersiefen, Ewa Zeslawska, Matthias J.E. Arlt, Uwe Jacob, Achim Krüger, Jörg Stürzebecher, Andrea Schweinitz, Ingo J. Banke, Oliver Schuster
Publikováno v:
The Journal of biological chemistry. 279(32)
The serine protease urokinase-type plasminogen activator (uPA) interacts with a specific receptor (uPAR) on the surface of various cell types, including tumor cells, and plays a crucial role in pericellular proteolysis. High levels of uPA and uPAR of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4ba787a3b204f3b213397d8f4f2de83
https://pubmed.ncbi.nlm.nih.gov/15150279
https://pubmed.ncbi.nlm.nih.gov/15150279