Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Anne, Ripperger"'
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 12 (2022)
Background The small GTPase RhoA (Ras homolog gene family, member A) regulates a variety of cellular processes, including cell motility, proliferation, survival, and permeability. In addition, there are reports indicating that RhoA‐ROCK (rho associ
Externí odkaz:
https://doaj.org/article/22f89d1dd5d046ff94bc8c42f27b408d
Autor:
Heike Braun, Michael Hauke, Anne Ripperger, Christian Ihling, Matthew Fuszard, Robert Eckenstaler, Ralf A. Benndorf
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 9855 (2021)
RNAi-mediated knockdown of DICER1 and DROSHA, enzymes critically involved in miRNA biogenesis, has been postulated to affect the homeostasis and the angiogenic capacity of human endothelial cells. To re-evaluate this issue, we reduced the expression
Externí odkaz:
https://doaj.org/article/6256740dcd5846f6ba951259fdd45d60
Autor:
Heike Braun, Michael Hauke, Robert Eckenstaler, Markus Petermann, Anne Ripperger, Niklas Kühn, Edzard Schwedhelm, Beatrice Ludwig-Kraus, Frank Bernhard Kraus, Virginie Dubourg, Alma Zernecke, Barbara Schreier, Michael Gekle, Ralf A. Benndorf
Publikováno v:
Free Radical Biology and Medicine. 185:36-45
The F2-isoprostane 8-iso-PGF2α (also known as 15-F2t-isoprostane, iPF2α-III, 8-epi PGF2α, 15(S)-8-iso-PGF2α, or 8-Isoprostane), a thromboxane A2 receptor (TP) agonist, stable biomarker of oxidative stress, and risk marker of cardiovascular diseas
Autor:
Robert Eckenstaler, Anne Ripperger, Michael Hauke, Markus Petermann, Sandra A. Hemkemeyer, Edzard Schwedhelm, Süleyman Ergün, Maike Frye, Oliver Werz, Andreas Koeberle, Heike Braun, Ralf A. Benndorf
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42:444-461
Background: TP (thromboxane A 2 receptor) plays an eminent role in the pathophysiology of endothelial dysfunction and cardiovascular disease. Moreover, its expression is reported to increase in the intimal layer of blood vessels of cardiovascular hig
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
The ATP-binding cassette transporter ABCG2 (BCRP and MXR) is involved in the absorption, distribution, and elimination of numerous drugs. Thus, drugs that are able to reduce the activity of ABCG2, e.g., antihypertensive AT1 receptor antagonists (ARBs
Externí odkaz:
https://doaj.org/article/01d5f65a2c54425d8fb626000cb173bf
Autor:
Robert Eckenstaler, Anne Ripperger, Michael Hauke, Edzard Schwedhelm, Süleyman Ergün, Oliver Werz, Andreas Koeberle, Heike Braun, Ralf Benndorf
Background and purpose: The thromboxane A2 receptor (TP) plays an eminent role in the pathophysiology of endothelial dysfunction and cardiovascular disease. Moreover, its expression is reported to increase in the intimal layer of blood vessels of car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea1a421d5c68e1ee1c792808799d6282
https://doi.org/10.22541/au.164864316.63985525/v1
https://doi.org/10.22541/au.164864316.63985525/v1
Autor:
Robert, Eckenstaler, Anne, Ripperger, Michael, Hauke, Heike, Braun, Süleyman, Ergün, Edzard, Schwedhelm, Ralf A, Benndorf
Publikováno v:
Biochemical pharmacology. 201
We could previously show that thromboxane A
Autor:
Robert Eckenstaler, Anne Ripperger, Michael Hauke, Heike Braun, Süleyman Ergün, Edzard Schwedhelm, Ralf Anton Benndorf
Publikováno v:
SSRN Electronic Journal.
Autor:
Robert Eckenstaler, Anne Ripperger, Michael Hauke, Heike Braun, Süleyman Ergün, Edzard Schwedhelm, Ralf A. Benndorf
Publikováno v:
Biochemical Pharmacology. 201:115069
Autor:
Anne Ripperger, Jochen Bauer, Ralf A. Benndorf, Süleyman Ergün, Stefan Frantz, Edzard Schwedhelm
Publikováno v:
British Journal of Pharmacology. 171:3115-3131
Isoprostanes are free radical-catalysed PG-like products of unsaturated fatty acids, such as arachidonic acid, which are widely recognized as reliable markers of systemic lipid peroxidation and oxidative stress in vivo. Moreover, activation of enzyme