Zobrazeno 1 - 10
of 229
pro vyhledávání: '"Anne, McArdle"'
Autor:
Jose Viña, Chiara Milanese, Federico Schena, Anne McArdle, Malcolm J Jackson, Gabriele Di Sante, Cinzia Antognelli, Anna Pedrinolla, Masoud Isanejad, Desirée Bartolini, Consuelo Borras, Valentina Cavedon, Anna Migni, Cristina Mas-Bargues, Claudia Baschirotto, Roberto Modena, Alessandra Pistilli, Mario Rende, Anna Maria Stabile, Nicola Vincenzo Telesa, Sara Tortorella, Kay Hemmings, Eivind Wang, Massimo Venturelli, Francesco Galli
Publikováno v:
BMJ Open, Vol 13, Iss 12 (2023)
Objective Protein–energy malnutrition and the subsequent muscle wasting (sarcopenia) are common ageing complications. It is knowing to be also associated with dementia. Our programme will test the cytoprotective functions of vitamin E combined with
Externí odkaz:
https://doaj.org/article/055d0bab960846cd87876378e15e0247
Autor:
Yalda A. Kharaz, Katarzyna Goljanek‐Whysall, Gareth Nye, Jane L. Hurst, Anne McArdle, Eithne J. Comerford
Publikováno v:
Physiological Reports, Vol 10, Iss 16, Pp n/a-n/a (2022)
Abstract Cruciate ligaments (CL) of the knee joint are injured following trauma or aging. MicroRNAs (miRs) are potential therapeutic targets in musculoskeletal disorders, but there is little known about the role of miRs and their expression ligaments
Externí odkaz:
https://doaj.org/article/4db5bd6fd2d54c6c85fb4056f40aa7bd
Autor:
Steve D. Guzman, Jennifer Judge, Shahjahan M. Shigdar, Thomas A. Paul, Carol S. Davis, Peter C. Macpherson, James F. Markworth, Holly Van Remmen, Arlan Richardson, Anne McArdle, Susan V. Brooks
Publikováno v:
Frontiers in Aging, Vol 2 (2022)
Aging results in the progressive accumulation of senescent cells in tissues that display loss of proliferative capacity and acquire a senescence-associated secretory phenotype (SASP). The tumor suppressor, p16INK4A, which slows the progression of the
Externí odkaz:
https://doaj.org/article/624eb338e7c1447186d014f1dd94f006
Publikováno v:
Cells, Vol 11, Iss 10, p 1698 (2022)
Research over almost 40 years has established that reactive oxygen species are generated at different sites in skeletal muscle and that the generation of these species is increased by various forms of exercise. Initially, this was thought to be poten
Externí odkaz:
https://doaj.org/article/4bfff4b33157487e887096add5cf66dd
Publikováno v:
Redox Biology, Vol 35, Iss , Pp 101484- (2020)
Hydrogen peroxide appears to be the key reactive oxygen species involved in redox signalling, but comparisons of the low concentrations of hydrogen peroxide that are calculated to exist within cells with those previously shown to activate common sign
Externí odkaz:
https://doaj.org/article/70def8b334e8497a89b61c2b658ddbff
Autor:
Mattia Scalabrin, Natalie Pollock, Caroline A. Staunton, Susan V. Brooks, Anne McArdle, Malcolm J. Jackson, Aphrodite Vasilaki
Publikováno v:
Redox Biology, Vol 26, Iss , Pp - (2019)
Previous studies have shown a significant increase in the mitochondrial generation of hydrogen peroxide (H2O2) and other peroxides in recently denervated muscle fibers. The mechanisms for generation of these peroxides and how the muscle responds to t
Externí odkaz:
https://doaj.org/article/96d2a5c4d3e945f595d9f718d64cfaf6
Autor:
Anne McArdle, Samuel Pringle, Jekaterina Kumiscia, Kay Hemmings, Desiree Bartolini, Anna Migni, Massimo Venturelli, Jose Vina, Francesco Galli, Malcolm Jackson
Publikováno v:
Physiology. 38
Skeletal muscle mass and function is decreased as we age, a condition known as sarcopenia. Ageing is associated with increases in minimum and mean cortisol plasma levels and shortening of the evening cortisol quiescent period, suggesting impaired cir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4257d4613e693e970c47b0f2185a71d
https://doi.org/10.1152/physiol.2023.38.s1.5735268
https://doi.org/10.1152/physiol.2023.38.s1.5735268
Autor:
Thomas A. Paul, Peter C. Macpherson, Tara L. Janetzke, Carol S. Davis, Malcolm J. Jackson, Anne McArdle, Susan V. Brooks
Publikováno v:
GeroScience.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::564dfb16d1b4923dbe4e8d5d7e289c43
https://doi.org/10.1007/s11357-023-00774-w
https://doi.org/10.1007/s11357-023-00774-w
Autor:
Kavithalakshmi Sataranatarajan, Rizwan Qaisar, Carol Davis, Giorgos K. Sakellariou, Aphrodite Vasilaki, Yiqiang Zhang, Yuhong Liu, Shylesh Bhaskaran, Anne McArdle, Malcolm Jackson, Susan V. Brooks, Arlan Richardson, Holly Van Remmen
Publikováno v:
Redox Biology, Vol 5, Iss , Pp 140-148 (2015)
Our previous studies showed that adult (8 month) mice lacking CuZn-superoxide dismutase (CuZnSOD, Sod1KO mice) have neuromuscular changes resulting in dramatic accelerated muscle atrophy and weakness that mimics age-related sarcopenia. We have furthe
Externí odkaz:
https://doaj.org/article/68ada85f180744b49b4e7e265f79dec8
Autor:
Benjamin R. Tollitt, Samantha W. Jones, Kai F. Hoettges, James R. Henstock, Gianluca Neri, Malcolm J. Jackson, Anne McArdle
Publikováno v:
Biophysical Journal. 122:433a-434a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1a1c46abc7fb1dabbc2993d3d2967d6
https://doi.org/10.1016/j.bpj.2022.11.2344
https://doi.org/10.1016/j.bpj.2022.11.2344