Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Anne, Largeot"'
Autor:
Camille Sauter, Thomas Morin, Fabien Guidez, John Simonet, Cyril Fournier, Céline Row, Denis Masnikov, Baptiste Pernon, Anne Largeot, Aziza Aznague, Yann Hérault, Guy Sauvageau, Marc Maynadié, Mary Callanan, Jean-Noël Bastie, Romain Aucagne, Laurent Delva
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Arginine methylation is catalyzed by protein arginine methyltransferases (PRMTs) and is involved in various cellular processes, including cancer development. PRMT2 expression is increased in several cancer types although its role in acute my
Externí odkaz:
https://doaj.org/article/967c7436105d4631865893350841f114
Targeting mRNA translation aberrations: A novel approach for therapy in chronic lymphocytic leukemia
Publikováno v:
Cancer Communications, Vol 43, Iss 12, Pp 1373-1376 (2023)
Externí odkaz:
https://doaj.org/article/cfbdd2fc7dad421da286dc5422792a12
Autor:
Anne Largeot, Vanessa Klapp, Elodie Viry, Susanne Gonder, Iria Fernandez Botana, Arnaud Blomme, Mohaned Benzarti, Sandrine Pierson, Chloé Duculty, Petra Marttila, Marina Wierz, Ernesto Gargiulo, Giulia Pagano, Ning An, Najla El Hachem, Daniel Perez Hernandez, Supriya Chakraborty, Loic Ysebaert, Jean-Hugues François, Susan Cortez, Guy Berchem, Dimitar G Efremov, Gunnar Dittmar, Martyna Szpakowska, Andy Chevigne, Petr V. Nazarov, Thomas Helleday, Pierre Close, Johannes Meiser, Basile Stamatopoulos, Laurent Désaubry, Jérôme Paggetti, Etienne Moussay
Publikováno v:
HemaSphere, Vol 7, p e52627ab (2023)
Externí odkaz:
https://doaj.org/article/cadb7e0ab439425bb2d02339f658e7b0
Autor:
Giulia Pagano, Iria Fernandez Botana, Marina Wierz, Philipp M. Roessner, Nikolaos Ioannou, Xiangda Zhou, Gheed Al-Hity, Coralie Borne, Ernesto Gargiulo, Susanne Gonder, Bin Qu, Basile Stamatopoulos, Alan G. Ramsay, Martina Seiffert, Anne Largeot, Etienne Moussay, Jerome Paggetti
Publikováno v:
Haematologica, Vol 108, Iss 11 (2023)
Chronic lymphocytic leukemia (CLL) cells are highly dependent on interactions with the immunosuppressive tumor microenvironment (TME) for survival and proliferation. In the search for novel treatments, pro-inflammatory cytokines have emerged as candi
Externí odkaz:
https://doaj.org/article/f29683a86d924b2e8fdf058bdcf1c6eb
Autor:
Hannah Wurzer, Liza Filali, Céline Hoffmann, Max Krecke, Andrea Michela Biolato, Jérôme Mastio, Sigrid De Wilde, Jean Hugues François, Anne Largeot, Guy Berchem, Jérôme Paggetti, Etienne Moussay, Clément Thomas
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Natural killer (NK) cells are innate effector lymphocytes with strong antitumor effects against hematologic malignancies such as chronic lymphocytic leukemia (CLL). However, NK cells fail to control CLL progression on the long term. For effective lys
Externí odkaz:
https://doaj.org/article/6022f7d32a004eda80782d5d6124ada7
Autor:
Susanne Gonder, Iria Fernandez Botana, Marina Wierz, Giulia Pagano, Ernesto Gargiulo, Antonio Cosma, Etienne Moussay, Jerome Paggetti, Anne Largeot
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
In the past 20 years, the interest for the tumor microenvironment (TME) has exponentially increased. Indeed, it is now commonly admitted that the TME plays a crucial role in cancer development, maintenance, immune escape and resistance to therapy. Th
Externí odkaz:
https://doaj.org/article/6971d99fbf1d4e66b075a4ddf3de045c
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Extracellular vesicles (EV), comprising microvesicles and exosomes, are particles released by every cell of an organism, found in all biological fluids, and commonly involved in cell-to-cell communication through the transfer of cargo materials such
Externí odkaz:
https://doaj.org/article/fce4aba91472435b955df413114ae257
Autor:
Ernesto Gargiulo, Elodie Viry, Pablo Elías Morande, Anne Largeot, Susanne Gonder, Feng Xian, Nikolaos Ioannou, Mohaned Benzarti, Felix Bruno Kleine Borgmann, Michel Mittelbronn, Gunnar Dittmar, Petr V. Nazarov, Johannes Meiser, Basile Stamatopoulos, Alan G. Ramsay, Etienne Moussay, Jérôme Paggetti
Publikováno v:
Gargiulo, E, Viry, E, Morande, P E, Largeot, A, Gonder, S, Xian, F, Ioannou, N, Benzarti, M, Kleine Borgmann, F B, Mittelbronn, M, Dittmar, G, Nazarov, P V, Meiser, J, Stamatopoulos, B, Ramsay, A G, Moussay, E & Paggetti, J 2022, ' Extracellular vesicle secretion by leukemia cells in vivo promotes CLL progression by hampering antitumor T-cell responses ', Blood Cancer Discovery . https://doi.org/10.1158/2643-3230.BCD-22-0029
Small extracellular vesicle (sEV, or exosome) communication among cells in the tumor microenvironment has been modeled mainly in cell culture, whereas their relevance in cancer pathogenesis and progression in vivo is less characterized. Here we inves
Autor:
Susanne Gonder, Anne Largeot, Ernesto Gargiulo, Sandrine Pierson, Iria Fernandez Botana, Giulia Pagano, Jerome Paggetti, Etienne Moussay
Publikováno v:
Cancers, Vol 13, Iss 18, p 4518 (2021)
Chronic lymphocytic leukemia (CLL) is the most frequent leukemia in the elderly and is characterized by the accumulation of mature B lymphocytes in peripheral blood and primary lymphoid organs. In order to proliferate, leukemic cells are highly depen
Externí odkaz:
https://doaj.org/article/604782341c1c437baa58a490aef9d092
Autor:
Anne Largeot, Vanessa Klapp, Elodie Viry, Susanne Gonder, Iria Fernandez Botana, Arnaud Blomme, Mohaned Benzarti, Sandrine Pierson, Chloé Duculty, Petra Marttila, Marina Wierz, Ernesto Gargiulo, Giulia Pagano, Ning An, Najla El Hachem, Daniel Perez Hermandez, Supriya Chakraborty, Loïc Ysebaert, Jean-Hugues François, Susan Denisse Cortez Clemente, Guy Berchem, Dimitar G Efremov, Gunnar Dittmar, Martyna Szpakowska, Andy Chevigne, Petr V Nazarov, Thomas Helleday, Pierre Close, Johannes Meiser, Basile Stamatopoulos, Laurent Désaubry, Jerome Paggetti, Etienne Moussay
Publikováno v:
Blood Journal.
Dysregulation of mRNA translation, including preferential translation of mRNA with complex 5'-UTRs such as the MYC oncogene, is recognized as an important mechanism in cancer. In this study, we show that both human and murine chronic lymphocytic leuk