A systematic review of progranulin concentrations in biofluids in over 7,000 people—assessing the pathogenicity of GRN mutations and other influencing factors

Autor: Imogen J. Swift, Rosa Rademakers, NiCole Finch, Matt Baker, Roberta Ghidoni, Luisa Benussi, Giuliano Binetti, Giacomina Rossi, Matthis Synofzik, Carlo Wilke, David Mengel, Caroline Graff, Leonel T. Takada, Raquel Sánchez-Valle, Anna Antonell, Daniela Galimberti, Chiara Fenoglio, Maria Serpente, Marina Arcaro, Stefanie Schreiber, Stefan Vielhaber, Philipp Arndt, Isabel Santana, Maria Rosario Almeida, Fermín Moreno, Myriam Barandiaran, Alazne Gabilondo, Johannes Stubert, Estrella Gómez-Tortosa, Pablo Agüero, M. José Sainz, Tomohito Gohda, Maki Murakoshi, Nozomu Kamei, Sarah Kittel-Schneider, Andreas Reif, Johannes Weigl, Jinlong Jian, Chuanju Liu, Ginette Serrero, Thomas Greither, Gerit Theil, Ebba Lohmann, Stefano Gazzina, Silvia Bagnoli, Giovanni Coppola, Amalia Bruni, Mirja Quante, Wieland Kiess, Andreas Hiemisch, Anne Jurkutat, Matthew S. Block, Aaron M. Carlson, Geir Bråthen, Sigrid Botne Sando, Gøril Rolfseng Grøntvedt, Camilla Lauridsen, Amanda Heslegrave, Carolin Heller, Emily Abel, Alba Gómez-Núñez, Roger Puey, Andrea Arighi, Enmanuela Rotondo, Lize C. Jiskoot, Lieke H. H. Meeter, João Durães, Marisa Lima, Miguel Tábuas-Pereira, João Lemos, Bradley Boeve, Ronald C. Petersen, Dennis W. Dickson, Neill R. Graff-Radford, Isabelle LeBer, Leila Sellami, Foudil Lamari, Fabienne Clot, Barbara Borroni, Valentina Cantoni, Jasmine Rivolta, Alberto Lleó, Juan Fortea, Daniel Alcolea, Ignacio Illán-Gala, Lucie Andres-Cerezo, Philip Van Damme, Jordi Clarimon, Petra Steinacker, Emily Feneberg, Markus Otto, Emma L. van der Ende, John C. van Swieten, Harro Seelaar, Henrik Zetterberg, Aitana Sogorb-Esteve, Jonathan D. Rohrer

Publikováno v: Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-13 (2024)

Abstract Background Pathogenic heterozygous mutations in the progranulin gene (GRN) are a key cause of frontotemporal dementia (FTD), leading to significantly reduced biofluid concentrations of the progranulin protein (PGRN). This has led to a number

Externí odkaz: https://doaj.org/article/1d7c751ac55c494a90e49ef788756561

Atopic diseases in children and adolescents are associated with behavioural difficulties

Autor: Wiebke Keller, Mandy Vogel, Freerk Prenzel, Jon Genuneit, Anne Jurkutat, Cornelia Hilbert, Andreas Hiemisch, Wieland Kiess, Tanja Poulain

Publikováno v: BMC Pediatrics, Vol 21, Iss 1, Pp 1-10 (2021)

Abstract Background Atopic diseases and behavioural difficulties in children have both been on the rise in recent decades. This study seeks to assess associations between atopic diseases and behavioural difficulties, examining the differences conside

Externí odkaz: https://doaj.org/article/d371a8390081446493273a7b95ea29ab

COVID-19 pandemic and families' utilization of well-child clinics and pediatric practices attendance in Germany

Autor: Mandy Vogel, Christoph Beger, Ruth Gausche, Anne Jurkutat, Roland Pfaeffle, Antje Körner, Christof Meigen, Tanja Poulain, Wieland Kiess

Publikováno v: BMC Research Notes, Vol 14, Iss 1, Pp 1-3 (2021)

Abstract Objective The COVID-19 pandemic and the measures implemented to stop the pandemic had a broad impact on our daily lives. Besides work and social life, health care is affected on many levels. In particular, there is concern that attendance in

Externí odkaz: https://doaj.org/article/910dbd8f11e14c348c3d79a8f997a26c

Motor skills in relation to body-mass index, physical activity, TV-watching, and socioeconomic status in German four-to-17-year-old children.

Autor: Siegfried Möller, Tanja Poulain, Antje Körner, Christof Meigen, Anne Jurkutat, Mandy Vogel, Sven Wessela, Andreas Hiemisch, Nico Grafe, Wieland Kiess

Publikováno v: PLoS ONE, Vol 16, Iss 5, p e0251738 (2021)

BackgroundThe present study describes motor skills in a large sample of German children and adolescents and investigates associations with age, gender, body-mass index, physical activity, television time, and socioeconomic status.Methods2,106 childre

Externí odkaz: https://doaj.org/article/8d97ac818ace4eef98335978fa766a29

Cross-sectional and longitudinal associations of screen time and physical activity with school performance at different types of secondary school

Autor: Tanja Poulain, Thomas Peschel, Mandy Vogel, Anne Jurkutat, Wieland Kiess

Publikováno v: BMC Public Health, Vol 18, Iss 1, Pp 1-10 (2018)

Abstract Background Previous studies have already reported associations of media consumption and/or physical activity with school achievement. However, longitudinal studies investigating independent effects of physical activity and media consumption

Externí odkaz: https://doaj.org/article/c7f47b02fa04487ab12514d177215345