Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Anne, Hultquist"'
Autor:
Axel Hyrenius-Wittsten, Mattias Pilheden, Helena Sturesson, Jenny Hansson, Michael P. Walsh, Guangchun Song, Julhash U. Kazi, Jian Liu, Ramprasad Ramakrishan, Cristian Garcia-Ruiz, Stephanie Nance, Pankaj Gupta, Jinghui Zhang, Lars Rönnstrand, Anne Hultquist, James R. Downing, Karin Lindkvist-Petersson, Kajsa Paulsson, Marcus Järås, Tanja A. Gruber, Jing Ma, Anna K. Hagström-Andersson
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
In acute leukemia with KMT2A rearrangements (KMT2A-R), activating signaling mutations are common. Here, the authors use a retroviral acute myeloid mouse leukemia model to show that subclonal de novo activating mutations drive clonal evolution in acut
Externí odkaz:
https://doaj.org/article/90c8b9707fb44780aabe13e7a04984b5
Publikováno v:
Stem Cells International, Vol 2018 (2018)
Acute myeloid leukemia (AML) has poor prognosis due to various mutations, e.g., in the FLT3 gene. Therefore, it is important to identify pathways regulated by the activated Flt3 receptor for the discovery of new therapeutic targets. The Myc network o
Externí odkaz:
https://doaj.org/article/206baed401874d528c710599e631c06b
Publikováno v:
Blood. 140:5784-5785
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba4eeea166f5f054f39a33cc3bea6848
https://doi.org/10.1182/blood-2022-166091
https://doi.org/10.1182/blood-2022-166091
Autor:
Anne Hultquist, Helena Sturesson, Jian Liu, Helena Ågerstam, Antoni Falqués-Costa, Axel Hyrenius-Wittsten, Mia Eriksson, Pauline Schneider, Marcus Järås, Mattias Pilheden, Cristian Garcia-Ruiz, Ronald W. Stam, Priscilla Wander, Henrik Lilljebjörn, Anna Hagström-Andersson
Publikováno v:
Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::661ee9a0257c93ceeaccaaa0d205e6e8
https://doi.org/10.1038/s41375-019-0465-1
https://doi.org/10.1038/s41375-019-0465-1
Autor:
Jing Ma, Axel Hyrenius-Wittsten, Helena Sturesson, Pankaj Gupta, Michael P. Walsh, Karin Lindkvist-Petersson, Jenny Hansson, Stephanie Nance, Anne Hultquist, Tanja A. Gruber, Anna Hagström-Andersson, Marcus Järås, Mattias Pilheden, Guangchun Song, Ramprasad Ramakrishan, Lars Rönnstrand, James R. Downing, Jinghui Zhang, Cristian Garcia-Ruiz, Julhash U. Kazi, Jian Liu, Kajsa Paulsson
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
BASE-Bielefeld Academic Search Engine
Nature Communications
BASE-Bielefeld Academic Search Engine
Nature Communications
Activating signaling mutations are common in acute leukemia with KMT2A (previously MLL) rearrangements (KMT2A-R). These mutations are often subclonal and their biological impact remains unclear. Using a retroviral acute myeloid mouse leukemia model,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a7e02305be98f74184dd491921b9a7
http://link.springer.com/article/10.1038/s41467-018-04180-1
http://link.springer.com/article/10.1038/s41467-018-04180-1
Autor:
Christina Jensen, Marella F. T. R. de Bruijn, Ewa Sitnicka, Adam J. Mead, Elisa Gomez Perdiguero, Shabnam Kharazi, Qiaolin Deng, Deborah Atkinson, Frederic Geissmann, Luca Melchiori, Anne Hultquist, Iain C. Macaulay, Emanuele Azzoni, Joana Carrelha, Sidinh Luc, Annica Pontén, Joanna C. A. Green, Sten Eirik W. Jacobsen, Isabelle Godin, Tiphaine Bouriez-Jones, Tiago C. Luis, Petter S. Woll, Michael Lutteropp, Rickard Sandberg, Gemma Swiers, Charlotta Böiers
Publikováno v:
Cell Stem Cell
Cell Stem Cell, Cambridge, MA : Cell Press, 2013, 13 (5), pp.535-548. ⟨10.1016/j.stem.2013.08.012⟩
Scopus-Elsevier
BASE-Bielefeld Academic Search Engine
Cell Stem Cell, Cambridge, MA : Cell Press, 2013, 13 (5), pp.535-548. ⟨10.1016/j.stem.2013.08.012⟩
Scopus-Elsevier
BASE-Bielefeld Academic Search Engine
In jawed vertebrates, development of an adaptive immune-system is essential for protection of the born organism against otherwise life-threatening pathogens. Myeloid cells of the innate immune system are formed early in development, whereas lymphopoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbdd0e028c64c42160d3dd91441f8ed5
https://doi.org/10.1016/j.stem.2013.08.012
https://doi.org/10.1016/j.stem.2013.08.012
Autor:
Jesper Kofoed Damm, Anne Hultquist, Mats Jerkeman, Mats Ehinger, Urban Gullberg, Sandra Gordon, Kristina Drott
Publikováno v:
Experimental hematology & oncology; 4(4) (2015)
Experimental Hematology & Oncology
Experimental Hematology & Oncology
Background: Epigenetic code modifications by histone deacetylase inhibitors (HDACi) have been proposed as potential new therapies for lymphoid malignancies. Diffuse large B-cell lymphoma (DLBCL) is the most common type of aggressive lymphoma for whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::264caf6a916d26e787385aaf04d3fdc7
https://doi.org/10.1186/2162-3619-4-4
https://doi.org/10.1186/2162-3619-4-4
Autor:
Yutaka Sasaki, Mikael Sigvardsson, Anne Hultquist, David Bryder, Sten Eirik W. Jacobsen, Karina Liuba, Kristina Anderson, Jörgen Adolfsson, Robert Månsson, Liping Yang, O J Borge, Ewa Sitnicka, Natalija Buza-Vidas, Lina Thorén, Christina Jensen
Publikováno v:
Cell. 121(2):295-306
All blood cell lineages derive from a common hematopoietic stem cell (HSC). The current model implicates that the first lineage commitment step of adult pluripotent HSCs results in a strict separation into common lymphoid and common myeloid precursor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9179c68e29398e9ba59047188d7bb3
Autor:
Lars-Gunnar Larsson, Irina Guzhova, Kenneth Nilsson, Anne Hultquist, Sven Påhlman, Cihan Cetinkaya
Publikováno v:
International Journal of Cancer. 94:97-108
The prognosis of patients with advanced stages of neuroblastoma with N-myc amplification remains poor despite escalated therapy, a situation that has called for alternative therapeutic approaches. Neuroblastoma cells, which represent immature periphe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b1f745ead8329d6ba4068b904809345
https://doi.org/10.1002/ijc.1443
https://doi.org/10.1002/ijc.1443
Autor:
Claus Nerlov, Anne Hultquist, Shabnam Kharazi, D Atkinson, Adam J. Mead, Kristian Reckzeh, Ewa Sitnicka, Toshio Suda, Fumio Arai, Lars Rönnstrand, Natalija Buza-Vidas, Sidinh Luc, Charlotta Böiers, Zhi Ma, Kristina Masson, Anna Mansour, Jörg Cammenga, Helen Ferry, Sten Eirik W. Jacobsen
Publikováno v:
BASE-Bielefeld Academic Search Engine
Acquisition of homozygous activating growth factor receptor mutations might accelerate cancer progression through a simple gene-dosage effect. Internal tandem duplications (ITDs) of FLT3 occur in approximately 25% cases of acute myeloid leukemia and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4232723133c713f286dd43ed5d8ed533
http://ora.ox.ac.uk/objects/uuid:0e26f718-0cd2-4b78-9361-d93328a95144
http://ora.ox.ac.uk/objects/uuid:0e26f718-0cd2-4b78-9361-d93328a95144