Somatostatin analogues increase AIP expression in somatotropinomas, irrespective of Gsp mutations

Autor: Edoardo Alesse, Erika Peverelli, Filippo Ceccato, Sandra Rotondi, M. Angelini, Adrian Daly, Anna Spada, Felice Giangaspero, Francesca R. Buttarelli, Anne Barlier, Annarita Turchi, Vincenzo Esposito, Albert Beckers, Orlando Maiorani, Lilya Rostomyan, Céline Defilles, Gianluca Occhi, Carla Scaroni, Dominique Figarella-Branger, Maria-Antonietta Oliva, Marie Lise Jaffrain-Rea

Publikováno v: Endocrine-Related Cancer
Endocrine-Related Cancer, BioScientifica, 2013, 20 (5), pp.753-66. ⟨10.1530/ERC-12-0322⟩
Endocrine-Related Cancer, 2013, 20 (5), pp.753-66. ⟨10.1530/ERC-12-0322⟩

Germline aryl hydrocarbon receptor interacting protein (AIP) gene mutations confer a predisposition to pituitary adenoma (PA), predominantly GH-secreting (GH-PA). As recent data suggest a role for AIP in the pathogenesis of sporadic GH-PA and their r

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https://hal.archives-ouvertes.fr/hal-00966213