Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Annapurna, Vyakarnam"'
Autor:
Krista E. van Meijgaarden, Wenchao Li, Simone J. C. F. M. Moorlag, Valerie A. C. M. Koeken, Hans J. P. M. Koenen, Leo A. B. Joosten, Annapurna Vyakarnam, Asma Ahmed, Srabanti Rakshit, Vasista Adiga, Tom H. M. Ottenhoff, Yang Li, Mihai G. Netea, Simone A. Joosten
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Bacillus Calmette-Guèrin - vaccination induces not only protection in infants and young children against severe forms of tuberculosis, but also against non-tuberculosis related all-cause mortality. To delineate different factors influencing
Externí odkaz:
https://doaj.org/article/2176553ccf2643cf9ec6fb719ffcf68d
Autor:
Mangaiarkarasi S. Asokan, Roshni Florina Joan, Sudhir Babji, Girish Dayma, Prajitha Nadukkandy, Vinutha Subrahmanyam, Archana Pandey, Girish Malagi, Pooja Arya, Vibhuti Mahajan, Jayateerth Bhavikatti, Ketakee Pawar, Aishwarya Thorat, Priyanki Shah, Ramakrishna B. Goud, Bishnudeo Roy, Shon Rajukutty, Sushil Immanuel, Dhiraj Agarwal, Sankhanil Saha, Akshatha Shivaraj, Patricia Panikulam, Rajeshwari Shome, Shah-E-Jahan Gulzar, Anusmrithi U. Sharma, Ajinkya Naik, Shruti Talashi, Madhuri Belekar, Ritu Yadav, Poornima Khude, Mamatha V, Sudarshan Shivalingaiah, Urmila Deshmukh, Chinmayee Bhise, Manjiri Joshi, Leeberk Raja Inbaraj, Sindhulina Chandrasingh, Aurnab Ghose, Colin Jamora, Anandi S. Karumbati, Varadharajan Sundaramurthy, Avita Johnson, Naveen Ramesh, Nirutha Chetan, Chaitra Parthiban, Asma Ahmed, Srabanti Rakshit, Vasista Adiga, George D'souza, Vinay Rale, Carolin Elizabeth George, Jacob John, Anand Kawade, Akanksha Chaturvedi, Anu Raghunathan, Mary Dias, Anand Bhosale, Padinjat Raghu, L.S. Shashidhara, Annapurna Vyakarnam, Vineeta Bal, Gagandeep Kang, Satyajit Mayor
Publikováno v:
The Lancet Regional Health - Southeast Asia, Vol 22, Iss , Pp 100361- (2024)
Summary: Background: There are limited global data on head-to-head comparisons of vaccine platforms assessing both humoral and cellular immune responses, stratified by pre-vaccination serostatus. The COVID-19 vaccination drive for the Indian populati
Externí odkaz:
https://doaj.org/article/97b23212b93e4d7e94207bd587e0f140
Autor:
Srabanti Rakshit, Sudhir Babji, Chaitra Parthiban, Ramya Madhavan, Vasista Adiga, Sharon Eveline J, Nirutha Chetan Kumar, Asma Ahmed, Sudarshan Shivalingaiah, Nandini Shashikumar, Mamatha V, Avita Rose Johnson, Naveen Ramesh, Ramkrishna Goud B, Mangaiarkarasi Asokan, Satyajit Mayor, Gagandeep Kang, George D’souza, Mary Dias, Annapurna Vyakarnam
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-18 (2023)
Abstract Detailed characterisation of immune responses induced by COVID-19 vaccines rolled out in India: COVISHIELDTM (CS) and COVAXIN® (CO) in a pre-exposed population is only recently being discovered. We addressed this issue in subjects who recei
Externí odkaz:
https://doaj.org/article/30f5306b692f49f4b2a280fbe4ebd644
Autor:
Asma Ahmed, Himanshu Tripathi, Krista E. van Meijgaarden, Nirutha Chetan Kumar, Vasista Adiga, Srabanti Rakshit, Chaitra Parthiban, Sharon Eveline J, George D’Souza, Mary Dias, Tom H.M. Ottenhoff, Mihai G. Netea, Simone A. Joosten, Annapurna Vyakarnam
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107889- (2023)
Summary: This study characterized mechanisms of Bacille Calmette-Guérin (BCG) revaccination-induced trained immunity (TI) in India. Adults, BCG vaccinated at birth, were sampled longitudinally before and after a second BCG dose. BCG revaccination si
Externí odkaz:
https://doaj.org/article/fce1cd72060e42ce9998437586fcd60f
Autor:
Srabanti Rakshit, Vasista Adiga, Asma Ahmed, Chaitra Parthiban, Nirutha Chetan Kumar, Pratibha Dwarkanath, Sudarshan Shivalingaiah, Srishti Rao, George D’Souza, Mary Dias, Thomas J. A. Maguire, Katie J. Doores, Martijn Zoodsma, Busranur Geckin, Prokar Dasgupta, Sudhir Babji, Krista E. van Meijgaarden, Simone A. Joosten, Tom H. M. Ottenhoff, Yang Li, Mihai G. Netea, Kenneth D. Stuart, Stephen C. De Rosa, M. Juliana McElrath, Annapurna Vyakarnam
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
This proof-of-concept study tested if prior BCG revaccination can qualitatively and quantitively enhance antibody and T-cell responses induced by Oxford/AstraZeneca ChAdOx1nCoV-19 or COVISHIELD™, an efficacious and the most widely distributed vacci
Externí odkaz:
https://doaj.org/article/bc79bf4b1a8a4e5c9ddd03b87afafc55
Hydrogen sulfide blocks HIV rebound by maintaining mitochondrial bioenergetics and redox homeostasis
Autor:
Virender Kumar Pal, Ragini Agrawal, Srabanti Rakshit, Pooja Shekar, Diwakar Tumkur Narasimha Murthy, Annapurna Vyakarnam, Amit Singh
Publikováno v:
eLife, Vol 10 (2021)
A fundamental challenge in human immunodeficiency virus (HIV) eradication is to understand how the virus establishes latency, maintains stable cellular reservoirs, and promotes rebound upon interruption of antiretroviral therapy (ART). Here, we disco
Externí odkaz:
https://doaj.org/article/35a5d030ee5d45c9b0cb5541d055ac51
Autor:
Srabanti Rakshit, Nitin Hingankar, Shuba Varshini Alampalli, Vasista Adiga, Bharath K. Sundararaj, Pravat Nalini Sahoo, Greg Finak, Anto Jesuraj Uday Kumar J, Chirag Dhar, George D’Souza, Rashmi Govind Virkar, Manisha Ghate, Madhuri R. Thakar, Ramesh S. Paranjape, Stephen C. De Rosa, Tom H.M. Ottenhoff, Annapurna Vyakarnam
Publikováno v:
Cell Reports, Vol 33, Iss 9, Pp 108451- (2020)
Summary: HIV infection predisposes latent tuberculosis-infected (LTBI) subjects to active TB. This study is designed to determine whether HIV infection of LTBI subjects compromises the balanced Mycobacterium tuberculosis (Mtb)-specific T helper 17 (T
Externí odkaz:
https://doaj.org/article/81a63bfce56344609c4df45cb0d72869
Autor:
Ashwini Shete, Shubhangi Bichare, Vishwanath Pujari, Rashmi Virkar, Madhuri Thakar, Manisha Ghate, Sandip Patil, Annapurna Vyakarnam, Raman Gangakhedkar, Gaowa Bai, Toshiro Niki, Toshio Hattori
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Galectin-9 (Gal-9) and osteopontin (OPN) play immunomodulatory roles in tuberculosis and HIV infections. Evaluation of their levels as well as their interplay with different pro-inflammatory cytokines is critical to understand their role in immunopat
Externí odkaz:
https://doaj.org/article/4da59bad129846ba815a8c596d15bdd8
Autor:
Awanti Sambarey, Abhinandan Devaprasad, Abhilash Mohan, Asma Ahmed, Soumya Nayak, Soumya Swaminathan, George D'Souza, Anto Jesuraj, Chirag Dhar, Subash Babu, Annapurna Vyakarnam, Nagasuma Chandra
Publikováno v:
EBioMedicine, Vol 15, Iss C, Pp 112-126 (2017)
Efficient diagnosis of tuberculosis (TB) is met with multiple challenges, calling for a shift of focus from pathogen-centric diagnostics towards identification of host-based multi-marker signatures. Transcriptomics offer a list of differentially expr
Externí odkaz:
https://doaj.org/article/3cac491dde494248b5fd377efa4e7825
Autor:
Arunachalam Ramaiah, Soumya Nayak, Srabanti Rakshit, Abigail L. Manson, Thomas Abeel, Sivakumar Shanmugam, Pravat Nalini Sahoo, Anto Jesuraj Uday Kumar John, Jagadish Chandrabose Sundaramurthi, Sujatha Narayanan, George D'Souza, Paul von Hoegen, Tom H. M. Ottenhoff, Soumya Swaminathan, Ashlee M. Earl, Annapurna Vyakarnam
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Vaccines that confer protection through induction of adaptive T-cell immunity rely on understanding T-cell epitope (TCE) evolution induced by immune escape. This is poorly understood in tuberculosis (TB), an ancient, chronic disease, where CD4 T-cell
Externí odkaz:
https://doaj.org/article/4e5c85c661ec4e32818f2d09f587ac83