Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Annapoorna Prakash"'
Publikováno v:
The Lancet Regional Health - Southeast Asia, Vol 30, Iss , Pp 100489- (2024)
Summary: Bhutan is currently transforming its health system and has updated its Health Technology Assessment (HTA) framework. This revision is designed to prioritize health initiatives and ensure the sustainability of the health system. This updated
Externí odkaz:
https://doaj.org/article/6a392a3402184ff3943fe2c5596b093b
Autor:
Catarina Krug, Melissa Neuman, James E Rosen, Michelle Weinberger, Stefanie Wallach, Mary Lagaay, Melanie Punton, Annapoorna Prakash, Mussa Kelvin Nsanya, Philip Ayieko, Saidi Kapiga, Yewande P Ajayi, Emily E Crawford, Eskindir Tenaw, Mohammed Mussa, Som Kumar Shrestha, Christian Bottomley, James R Hargreaves, Aoife Margaret Doyle
Publikováno v:
PLOS Global Public Health, Vol 3, Iss 10, p e0002347 (2023)
Around half of adolescent pregnancies in low- and middle-income countries are unintended, contributing to millions of unsafe abortions per year. Adolescents 360 (A360), a girl-centred initiative, aimed to increase voluntary uptake of modern contracep
Externí odkaz:
https://doaj.org/article/376acbd6682e472fb264a2c6ad30f1b0
Autor:
Poornachandra G, Annapoorna Prakash, Prashant Ramachandran Nair, Anusha Pampana, Deepak Anil Lala, Vishwas Joseph, Kunal Ghosh Roy, Shruthi Kulkarni, Ashish Agarwal, Shweta Kapoor, Michael Castro, Rajan Parashar, Swaminathan Rajagopalan, Nikita Ray Choudhary, Liptimayee Behura, Aftab Alam, Sayani Basu
Publikováno v:
Journal of Neuro-Oncology
Background A randomized trial in glioblastoma patients with methylated-MGMT (m-MGMT) found an improvement in median survival of 16.7 months for combination therapy with temozolomide (TMZ) and lomustine, however the approach remains controversial and
Autor:
Michael Castro, Fabio Iwamoto, Manmeet Ahluwalia, Shahabuddin Usmani, Ansu Kumar, Shweta Kapoor, Rakhi Purushothaman Suseela, Shruthi Kulkarni, Jharana Mohanty, Vijayashree Shyamasundar, Adity Ghosh, Nagendra Prasad, Mamatha Patil, Sayantani Roy Choudhury, Jyoti Chauhan, Mohammed Sauban, Vishwas Joseph, Pallavi Kumari, Upasana Mitra, Anusha Pampana, Humera Azam, Poornachandra G, Annapoorna Prakash, Sayani Basu
Publikováno v:
Neuro-Oncology. 24:vii116-vii117
BACKGROUND TMZ-induced G:T mismatches trigger MMR to perform futile repair of O6-methylguanine leading to apoptosis. Without MMR, the G:T mutation is genomically incorporated to produce DNA mutation signature #11. Hypermutation ensues and may comprom
Autor:
Aftab Alam, Divya Singh, Liptimayee Behura, Anusha Pampana, Anish Raju R Amara, Negar Khanlou, Kunal Ghosh Roy, Michael Castro, Annapoorna Prakash, Ansu Kumar, Shweta Kapoor, Deepak Anil Lala, Aria Fallah
Publikováno v:
Annals of Translational Medicine. 10:1289-1289
Autor:
Mamatha Patil, Naga Ganesh Palaniyeppa, Diwyanshu Sahu, Yashaswini S Ullal, Kabya Basu, Jharana Mohanty, Vishwas Joseph, Upasana Mitra, Scott C. Howard, Mohammed Sauban, Ashokraja Balla, Vijayashree P Shyamasundar, S. Mohapatra, Annapoorna Prakash, Shweta Kapoor, Swati Khandelwal, Guido Marcucci, Liptimayee Behura, Deepak Anil Lala, Michele Dundas Macpherson, Sanjana Patel, Ansu Kumar, Karthik Sundara Raju, Michael Castro, Ashish Kumar Agrawal
Publikováno v:
Blood. 138:3550-3550
Background: Mantle Cell Lymphoma (MCL) accounts for 3-10% of all non-Hodgkin lymphomas with a median overall survival of 3-4 years. Hyper-CVAD (CVAD) with or without Rituximab constitutes first line therapy for treatment of MCL, yet the use of this c
Autor:
Michael Castro, Scott C Howard, Ansu Kumar, Vivek Patil, Swati Khandelwal, Drew Watson, Shweta Kapoor, Pallavi Kumari, Samiksha Avinash Prasad, Neha Gupta, Neelesh Lunkad, Upasana Mitra, Poornachandra G, Chandan Kumar, Sayantani Roy Choudhury, Shruthi Kulkarni, Ashish Choudhary, Annapoorna Prakash, Zakir Husain, Adity Ghosh, Yugandhara Narvekar, Anish Raju R Amara, Velkuru Yuvavani, Sanjana Patel, Michele Dundas Macpherson, Guido Marcucci
Publikováno v:
Blood. 138:1299-1299
Background: Genomic heterogeneity in leukemic blasts characterizes Acute Myeloid Leukemia (AML) patients and is associated to variable drug response. However, use of genomics to guide therapy has generally been restricted to a single-gene approach, w
Autor:
Drew Watson, Yashaswini S Ullal, Himanshu Grover, Shweta Kapoor, James Christie, Liptimayee Behura, Annapoorna Prakash, Prashant Ramachandran Nair, Michele Dundas Macpherson, Veena Balakrishnan, Rajan Parashar, Kunal Ghosh Roy, Aftab Alam, Diwyanshu Sahu, Kabya Basu, Yugandhara Narvekar, Adity Ghosh, Anthony S. Stein, Guido Marcucci, Swaminathan Rajagopalan, Nirjhar Mundkur
Publikováno v:
Blood. 136:9-10
Background: Therapy selection for MDS patients is often based on information considering only cytogenetics and single molecular aberrations and ignoring other patient-specific omics data that could potentially enable more effective treatments. In tur
Autor:
Nirjhar Mundkur, Vishwas Joseph, Adity Ghosh, Vijayashree P S, Yuvavani Velkuru, Vivek Patil, Yugandhara Narvekar, Michael Castro, Ashish Kumar Agrawal, Anuj Tyagi, Annapoorna Prakash, Ansu Kumar, Naga Ganesh, Karthik Sundara Raju, Pallavi Kumari, Yashaswini S Ullal, Himanshu Grover, Humera Azam, Poornachandra G
Publikováno v:
Journal of Clinical Oncology. 39:e16091-e16091
e16091 Background: Using a 5FU backbone, a variety of combination chemotherapy regimens have been adopted for gastric cancer. However, the genetic heterogeneity of the disease suggests certain drugs would lead to better outcomes for specific patients
Autor:
S. Mohapatra, Himanshu Grover, Chandan Kumar, Mamatha Patil, Anish Raju R Amara, Michael Castro, Ansu Kumar, Shruthi Kulkarni, Vamsidhar Velcheti, Annapoorna Prakash, Sayantani Roy Choudhury, Pallavi Kumari, Deepak Anil Lala, Samiksha Avinash Prasad, Nagendra K. Prasad, Rema Mandal, Nirjhar Mundkur, Liptimayee Behura, R. Gopi
Publikováno v:
Journal of Clinical Oncology. 39:e21211-e21211
e21211 Background: Cancer management using cytotoxic drugs is hampered by limited efficacy. Hence, a personalized treatment approach matching chemotherapy with appropriate patients remains a persistent and unmet need in the clinic. Genomic heterogene