Effect of PF-00547659 on Central Nervous System Immune Surveillance and Circulating beta 7+T Cells in Crohn's Disease: Report of the TOSCA Study

Autor: Richard M. Ransohoff, Olaf Stüve, Harald Vogelsang, Sunday Rivers, Clare Robert A, Kenneth J. Gorelick, Fabio Cataldi, Mina Hassan-Zahraee, Pierre Desreumaux, Geert R. D'Haens, John B. Cheng, Annamarie Kaminski, Yanhua Zhang, Alaa Ahmad, William J. Sandborn, Vivek Pradhan, Severine Vermeire, Matthieu Allez, André Van Gossum, Daniel C. Baumgart, Matthew O Sikpi, Gail M. Comer, Walter Reinisch

Publikováno v: Journal of Crohn's and Colitis, 12 (2
Journal of Crohn's & Colitis
Journal of Crohn s & colitis, 12(2), 188-196. Elsevier

Background and Aims: Progressive multifocal leukoencephalopathy [PML], a brain infection associated with anti-integrin drugs that inhibit lymphocyte translocation from bloodstream to tissue, can be fatal. Decreased central nervous system [CNS] immune

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0350cb62bfc1c41162f6824fc6910661
https://doi.org/10.1093/ecco-jcc/jjx128