Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Annamarie Mangine"'
Autor:
Deana S. Way, Robert A. Moran, Peter V.N. Bodine, Laura M. Seestaller-Wehr, Julia Billiard, Annamarie Mangine
Publikováno v:
Molecular Endocrinology. 19:90-101
Ror2 is an orphan receptor tyrosine kinase that plays crucial roles in developmental morphogenesis, particularly of the skeleton. We have identified human Ror2 as a novel regulator of canonical Wnt signaling in osteoblastic (bone-forming) cells with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9421e56990094c29fe4c180b5cbc454
https://doi.org/10.1210/me.2004-0153
https://doi.org/10.1210/me.2004-0153
Autor:
Mengxiao Shi, Laura M. Seestaller-Wehr, Peter V.N. Bodine, Helga Ponce-de-Leon, Barbara Stauffer, Annamarie Mangine, Robert Moran, Ariamala Gopalsamy, Girija Krishnamurthy, Julia Billiard, Shoichi Fukayama, Ramesh A. Bhat
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(22)
Secreted frizzled related protein-1 (sFRP-1) inhibitors have the potential to be used for the treatment of osteoporosis or other bone related disorders, since the level of sFRP-1 affects osteoblast apoptosis and proliferation. From high throughput sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33bd967816827b9d82087d6ae5588ed4
https://pubmed.ncbi.nlm.nih.gov/19819694
https://pubmed.ncbi.nlm.nih.gov/19819694
Autor:
Barbara Stauffer, Julia Billiard, Mengxiao Shi, Laura M. Seestaller-Wehr, Girija Krishnamurthy, Ramesh Bahat, Shoichi Fukayama, Helga Ponce-de-Leon, Annamarie Mangine, Robert Moran, Peter V.N. Bodine, Ariamala Gopalsamy
Publikováno v:
Journal of medicinal chemistry. 51(24)
Inhibitor of secreted frizzled related protein-1 (sFRP-1) would be a novel potential osteogenic agent, since loss of sFRP-1 affects osteoblast proliferation, differentiation, and activity, resulting in improved bone mineral density, quality, and stre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d21f9738e52000bc7246b31c7dd128
https://pubmed.ncbi.nlm.nih.gov/19053830
https://pubmed.ncbi.nlm.nih.gov/19053830
Autor:
Jeffrey Curtis Kern, Shoichi Fukayama, Gregory S. Welmaker, Mengxiao Shi, Thomas Joseph Commons, Richard Page Woodworth, Barry S. Komm, Robert A. Moran, Girija Krishnamurthy, Wilson Matthew Allan, Ramesh A. Bhat, Annamarie Mangine, Peter V.N. Bodine, Laura M. Seestaller-Wehr, William Jay Moore, Keith Pitts, Eugene John Trybulski, Barbara Stauffer, Julia Billiard, Ariamala Gopalsamy, Helga Ponce-de-Leon
Publikováno v:
Bone. 44(6)
Canonical Wnt signaling has been demonstrated to increase bone formation, and Wnt pathway components are being pursued as potential drug targets for osteoporosis and other metabolic bone diseases. Deletion of the Wnt antagonist secreted frizzled-rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca48c16a82a8b27c92ce162b2bb041c3
https://pubmed.ncbi.nlm.nih.gov/19254787
https://pubmed.ncbi.nlm.nih.gov/19254787
Autor:
Annamarie Mangine, Barry S. Komm, Robert A. Moran, Peter V.N. Bodine, Yan Liu, Laura M. Seestaller-Wehr, Shoichi Fukayama, Ramesh A. Bhat, Julia Billiard
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 21(2)
Ror2 is a receptor tyrosine kinase, the expression of which increases during differentiation of pluripotent stem cells to osteoblasts and then declines as cells progress to osteocytes. To test whether Ror2 plays a role in osteoblastogenesis, we inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a170544e44c1a41c07e966396c999b0
https://pubmed.ncbi.nlm.nih.gov/17095577
https://pubmed.ncbi.nlm.nih.gov/17095577
Autor:
Gary S. Stein, Ramesh A. Bhat, Annamarie Mangine, Jane B. Lian, Helga Ponce-de-Leon, Jack Green, Melissa J Scrimo, Peter V.N. Bodine, Barry S. Komm, Sean McLarney, Barbara Stauffer, Julia Billiard, Robert A. Moran
Publikováno v:
Journal of cellular biochemistry. 96(6)
Mechanisms controlling human bone formation remain to be fully elucidated. We have used differential display-polymerase chain reaction analysis to characterize osteogenic pathways in conditionally immortalized human osteoblasts (HOBs) representing di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39254e1a035a2350ba46b0423dc36398
https://pubmed.ncbi.nlm.nih.gov/16149051
https://pubmed.ncbi.nlm.nih.gov/16149051
Autor:
Stephen Caltabiano, Rita Francis, Gerardo D. Francisco, Frank E. Koehn, John W. Ellingboe, Zhen-jia Chen, David Gralnick, Mark Trailsmith, Yogendra P. Kharode, Adam M. Gilbert, Annamarie Mangine
Publikováno v:
Journal of medicinal chemistry. 45(11)
A series of pyrazolo[4,3-d]pyrimidine sulfonamides and pyrazolo[3,4-d]pyrimidine sulfonamides have been synthesized. These compounds increase transcription of a calcitonin-luciferase promoter and production of cellular calcitonin in a calcitonin-secr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf77326e6f66a9479dd2ddf79512a6ca
https://pubmed.ncbi.nlm.nih.gov/12014973
https://pubmed.ncbi.nlm.nih.gov/12014973
Autor:
Ariamala Gopalsamy, Mengxiao Shi, Barbara Stauffer, Ramesh Bahat, Julia Billiard, Helga Ponce-de-Leon, Laura Seestaller-Wehr, Shoichi Fukayama, Annamarie Mangine, Robert Moran, Girija Krishnamurthy, Peter Bodine
Publikováno v:
Journal of Medicinal Chemistry; Dec2008, Vol. 51 Issue 24, p7670-7672, 3p
Autor:
Peter V.N. Bodine, Julia Billiard, Robert A. Moran, Helga Ponce‐de‐Leon, Sean McLarney, Annamarie Mangine, Melissa J. Scrimo, Ramesh A. Bhat, Barbara Stauffer, Jack Green, Gary S. Stein, Jane B. Lian, Barry S. Komm
Publikováno v:
Journal of Cellular Biochemistry; Dec2005, Vol. 96 Issue 6, p1212-1230, 0p