Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Annamaria Regina"'
Autor:
Matteo Villa, David E. Sanin, Petya Apostolova, Mauro Corrado, Agnieszka M. Kabat, Carmine Cristinzio, Annamaria Regina, Gustavo E. Carrizo, Nisha Rana, Michal A. Stanczak, Francesc Baixauli, Katarzyna M. Grzes, Jovana Cupovic, Francesca Solagna, Alexandra Hackl, Anna-Maria Globig, Fabian Hässler, Daniel J. Puleston, Beth Kelly, Nina Cabezas-Wallscheid, Peter Hasselblatt, Bertram Bengsch, Robert Zeiser, Sagar, Joerg M. Buescher, Edward J. Pearce, Erika L. Pearce
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Immune cells must adapt to different environments during the course of an immune response. Here we study the adaptation of CD8+ T cells to the intestinal microenvironment and how this process shapes the establishment of the CD8+ T cell pool.
Externí odkaz:
https://doaj.org/article/94dc27161c6a48b2b42944d1f1be38af
Autor:
David, O'Sullivan, Michal A, Stanczak, Matteo, Villa, Franziska M, Uhl, Mauro, Corrado, Ramon I, Klein Geltink, David E, Sanin, Petya, Apostolova, Nisha, Rana, Joy, Edwards-Hicks, Katarzyna M, Grzes, Agnieszka M, Kabat, Ryan L, Kyle, Mario, Fabri, Jonathan D, Curtis, Michael D, Buck, Annette E, Patterson, Annamaria, Regina, Cameron S, Field, Francesc, Baixauli, Daniel J, Puleston, Edward J, Pearce, Robert, Zeiser, Erika L, Pearce
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Fever is a common symptom of infections and inflammation. We observed CD8+ T cells exposed to febrile-range temperature during activation, augmented mitochondrial mass, and metabolic activity. An adoptive transfer of these cells into tum
Autor:
Michael D. Buck, Daniel J. Puleston, Mario Fabri, Agnieszka M. Kabat, Katarzyna M. Grzes, Annamaria Regina, Michal A. Stanczak, Francesc Baixauli, Annette E. Patterson, Erika L. Pearce, Ryan Kyle, Joy Edwards-Hicks, Robert Zeiser, Ramon I. Klein Geltink, David E. Sanin, Petya Apostolova, David O’Sullivan, Jonathan D. Curtis, Cameron S. Field, Edward J. Pearce, Franziska M. Uhl, Matteo Villa, Mauro Corrado, Nisha Rana
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Fever can provide a survival advantage during infection. Metabolic processes are sensitive to environmental conditions, but the effect of fever on T cell metabolism is not well characterized. We show that in activated CD8+ T cells, exposure to febril