Výsledky vyhledávání - "Annamaria Megiovanni"

Epitope focus, clonal composition and Th1 phenotype of the human CD4 response to the secretory mycobacterial antigen Ag85

Autor: M. T. Valle, G. Li Pira, Luisa Lozzi, Fabrizio Manca, Annamaria Megiovanni, Andrea Merlo, Kris Huygen, Laura Bottone, Luisa Bracci, G. Angelini

Publikováno v: Clinical and experimental immunology. 123(2)

SUMMARYLymphoproliferation of healthy donors was tested against mycobacterial antigens (PPD, Ag85, Ag85 peptides). All PPD responders recognized the secretory antigen Ag85 and the peptide specificity for Ag85B was defined. Peptide 91–108 was recogn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bed84a1a498d3b8acec9beb20937c8e
https://pubmed.ncbi.nlm.nih.gov/11207652

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Requirement for different presenting cells and for different processing mechanisms by human CD4 T helper clones specific for M. tuberculosis antigens

Autor: Annalisa Kunkl, Giusi Li Pira, Annamaria Megiovanni, Laura Bottone, Andrea Merlo, Sabina Lantero, B Balbi, Paola Terranova, Giovanni A. Rossi, M. T. Valle, Daniela Fenoglio, Fabrizio Manca

Human T helper cells specific for mycobacterial antigens have been extensively investigated. Differences have been detected according to antigen specificity and to fine epitope specificity. In this work we have analyzed two additional parameters that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc01f9a31012e998d0ee58ae1d8e03ab
http://hdl.handle.net/11567/381919

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Handling of retroviral antigens by human antigen-presenting cells

Autor: Daniele Saverino, Fabrizio Manca, M. T. Valle, F. Buffa, Annamaria Megiovanni, Annalisa Kunkl, L. Oppezzi, Daniela Fenoglio, G. Li Pira, Gabriella Piatti, F. Lancia, Anna Maria Ferraris

Summary Antigen-specific T helper cells play an important role in retroviral infections. Indeed, they provide help for B-cell activation and antibody production and for clonal expansion of cytolytic lymphocytes. Therefore, we used retrovirus-specific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35749bd797b200d22328e77221237120
http://hdl.handle.net/11567/245856

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Natural analogue peptides of an HIV-1 GP120 T-helper epitope antagonize response of GP120-specific human CD4 T-cell clones

Autor: Andrea Merlo, Luisa Lozzi, Giuseppina Li Pira, S. Lantero, Daniele Saverino, Luisa Bracci, Fabrizio Manca, Annamaria Megiovanni, Laura Bottone, Paola Terranova, Daniela Fenoglio

Publikováno v: ResearcherID
Università degli Studi di Siena-IRIS
Scopus-Elsevier

Neutralizing antibodies and specific cytotoxic T lymphocytes (CTL) may contribute to controlling viral spread, and ideally, to virus clearance in HIV infection. Both effector mechanisms depend on specific CD4 T-helper (Th) cells. Nevertheless, HIV hy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b0ad8fb76dbba9952b67626c9e1cee
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000085496900001&KeyUID=WOS:000085496900001

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