Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Annamaria Lia"'
Autor:
Annamaria Lia, Gabriele Sansevero, Angela Chiavegato, Miriana Sbrissa, Diana Pendin, Letizia Mariotti, Tullio Pozzan, Nicoletta Berardi, Giorgio Carmignoto, Cristina Fasolato, Micaela Zonta
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Altered Ca2+ signaling is involved in the pathogenesis of Alzheimer’s disease. Here, the authors show Ca2+ hypoactivity in astrocytes at plaque deposition onset related to reduced expression of the Ca2+ sensor STIM1 and impaired synaptic plasticity
Externí odkaz:
https://doaj.org/article/2692d4385d9d452f9a4c2132e63f0f7d
Autor:
Annamaria Lia, Alessandro Di Spiezio, Lorenzo Vitalini, Manuela Tore, Giulia Puja, Gabriele Losi
Publikováno v:
Life, Vol 13, Iss 10, p 2038 (2023)
The human brain is composed of nearly one hundred billion neurons and an equal number of glial cells, including macroglia, i.e., astrocytes and oligodendrocytes, and microglia, the resident immune cells of the brain. In the last few decades, compelli
Externí odkaz:
https://doaj.org/article/1da67d8bf6aa4eacadb7a8131250e556
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3025 (2022)
Alzheimer’s disease (AD) is a hereditary and sporadic neurodegenerative illness defined by the gradual and cumulative loss of neurons in specific brain areas. The processes that cause AD are still under investigation and there are no available ther
Externí odkaz:
https://doaj.org/article/4aaa6027fd1a45f18b72e516dad7a73b
Autor:
Annamaria Lia, Vanessa Jorge Henriques, Micaela Zonta, Angela Chiavegato, Giorgio Carmignoto, Marta Gómez-Gonzalo, Gabriele Losi
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
The glial cells astrocytes have long been recognized as important neuron-supporting elements in brain development, homeostasis, and metabolism. After the discovery that the reciprocal communication between astrocytes and neurons is a fundamental mech
Externí odkaz:
https://doaj.org/article/acbca54c7b6b4f918bbe6450abc1ee94
Autor:
Elisa Greotti, Ilaria Fortunati, Diana Pendin, Camilla Ferrante, Luisa Galla, Lorena Zentilin, Mauro Giacca, Nina Kaludercic, Moises Di Sante, Letizia Mariotti, Annamaria Lia, Marta Gómez-Gonzalo, Michele Sessolo, Giorgio Carmignoto, Renato Bozio, Tullio Pozzan
Publikováno v:
iScience, Vol 16, Iss , Pp 340-355 (2019)
Summary: Genetically Encoded Ca2+ Indicators (GECIs) are extensively used to study organelle Ca2+ homeostasis, although some available probes are still plagued by a number of problems, e.g., low fluorescence intensity, partial mistargeting, and pH se
Externí odkaz:
https://doaj.org/article/68a895b0109142569ddc88129249e310
Autor:
Letizia Mariotti, Gabriele Losi, Annamaria Lia, Marcello Melone, Angela Chiavegato, Marta Gómez-Gonzalo, Michele Sessolo, Serena Bovetti, Angelo Forli, Micaela Zonta, Linda Maria Requie, Iacopo Marcon, Arianna Pugliese, Cécile Viollet, Bernhard Bettler, Tommaso Fellin, Fiorenzo Conti, Giorgio Carmignoto
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Interneurons in the neocortex have functional and morphological subtypes. Here, Mariotti and colleagues show that activation of parvalbumin-expressing interneurons evokes depressing calcium responses in astrocytes while somatostatin-expressing intern
Externí odkaz:
https://doaj.org/article/456179a2c5a54300b6477423f829937e
Autor:
Rosa Pia Norante, Caterina Peggion, Daniela Rossi, Francesca Martorana, Agnese De Mario, Annamaria Lia, Maria Lina Massimino, Alessandro Bertoli
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 20, p 5151 (2019)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the selective death of motor neurons (MNs), probably by a combination of cell- and non-cell-autonomous processes. The past decades have brought many important
Externí odkaz:
https://doaj.org/article/27574c08985942d3a5f50afbd1995a0c
Autor:
Linda Maria Requie, Marta Gómez-Gonzalo, Michele Speggiorin, Francesca Managò, Marcello Melone, Mauro Congiu, Angela Chiavegato, Annamaria Lia, Micaela Zonta, Gabriele Losi, Vanessa Jorge Henriques, Arianna Pugliese, Giada Pacinelli, Giovanni Marsicano, Francesco Papaleo, Anna Lisa Muntoni, Fiorenzo Conti, Giorgio Carmignoto
Publikováno v:
Nature Neuroscience. 25:1639-1650
The plasticity of glutamatergic transmission in the ventral tegmental area (VTA) represents a fundamental mechanism in the modulation of dopamine neuron burst firing and phasic dopamine release at target regions. These processes encode basic behavior
Autor:
Rosa Mastrogiacomo, Gabriella Trigilio, Céline Devroye, Daniel Dautan, Valentina Ferretti, Gabriele Losi, Lucia Caffino, Genny Orso, Roberto Marotta, Federica Maltese, Enrica Vitali, Gessica Piras, Alessia Forgiarini, Giada Pacinelli, Annamaria Lia, Debora A. Rothmond, John L. Waddington, Filippo Drago, Fabio Fumagalli, Maria Antonietta De Luca, Gian Marco Leggio, Giorgio Carmignoto, Cynthia S. Weickert, Francesca Managò, Francesco Papaleo
Publikováno v:
Molecular Psychiatry. 27:4201-4217
The mechanisms underlying the dichotomic cortical/basal ganglia dopaminergic abnormalities in schizophrenia are unclear. Astrocytes are important non-neuronal modulators of brain circuits, but their role in dopaminergic system remains poorly explored
Autor:
Linda Maria Requie, Marta Gómez-Gonzalo, Michele Speggiorin, Francesca Managò, Marcello Melone, Mauro Congiu, Angela Chiavegato, Annamaria Lia, Micaela Zonta, Gabriele Losi, Vanessa Jorge Henriques, Arianna Pugliese, Giada Pacinelli, Giovanni Marsicano, Francesco Papaleo, Anna Lisa Muntoni, Fiorenzo Conti, Giorgio Carmignoto
Publikováno v:
Nature Neuroscience.