Zobrazeno 1 - 10
of 230
pro vyhledávání: '"Annamaria Cimini"'
Autor:
Francesco D'Egidio, Vanessa Castelli, Michele d'Angelo, Fabrizio Ammannito, Massimiliano Quintiliani, Annamaria Cimini
Publikováno v:
Neurobiology of Disease, Vol 201, Iss , Pp 106663- (2024)
The functionality of the central nervous system (CNS) relies on the connection, integration, and the exchange of information among neural cells. The crosstalk among glial cells and neurons is pivotal for a series of neural functions, such as developm
Externí odkaz:
https://doaj.org/article/3d242c3620534af8992bc6258ba6743e
Autor:
Francesco D'Egidio, Vanessa Castelli, Giorgia Lombardozzi, Fabrizio Ammannito, Annamaria Cimini, Michele d'Angelo
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 9, Pp 1991-1997 (2024)
Huntington's disease is a neurodegenerative disease caused by the expansion mutation of a cytosine-adenine-guanine triplet in the exon 1 of the HTT gene which is responsible for the production of the huntingtin (Htt) protein. In physiological conditi
Externí odkaz:
https://doaj.org/article/6d3b3d099778440692b6af4e5ac9b1ac
Autor:
Vanessa Castelli, Michele d’Angelo, Francesca Zazzeroni, Davide Vecchiotti, Edoardo Alesse, Daria Capece, Laura Brandolini, Franca Cattani, Andrea Aramini, Marcello Allegretti, Annamaria Cimini
Publikováno v:
Cell Death and Disease, Vol 14, Iss 9, Pp 1-9 (2023)
Abstract Hearing loss impacts the quality of life and affects communication resulting in social isolation and reduced well-being. Despite its impact on society and economy, no therapies for age-related hearing loss are available so far. Loss of mecha
Externí odkaz:
https://doaj.org/article/7ae7b8e7693a4f3d91f3c7829b85aee6
Autor:
Andrea Antonosante, Vanessa Castelli, Martina Sette, Margherita Alfonsetti, Mariano Catanesi, Elisabetta Benedetti, Matteo Ardini, Annamaria Cimini, Michele d’Angelo
Publikováno v:
Biological Research, Vol 56, Iss 1, Pp 1-22 (2023)
Abstract Background The underlying mechanism of Parkinson’s disease are still unidentified, but excitotoxicity, oxidative stress, and neuroinflammation are considered key actors. Proliferator activated receptors (PPARs) are transcription factors in
Externí odkaz:
https://doaj.org/article/178c395877d247fa99a564896b677857
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 877 (2024)
Stroke is a common neurological disorder, the second leading cause of death, and the third leading cause of disability. Unfortunately, the only approved drug for it is tissue plasminogen, but the therapeutic window is limited. In this context, precli
Externí odkaz:
https://doaj.org/article/ee3812806c1b453eac347bd55a7a71fc
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 751 (2024)
Many anti-cancer drugs, such as taxanes, platinum compounds, vinca alkaloids, and proteasome inhibitors, can cause chemotherapy-induced peripheral neuropathy (CIPN). CIPN is a frequent and harmful side effect that affects the sensory, motor, and auto
Externí odkaz:
https://doaj.org/article/7eae16895e4a4b05b08d91a0a7e92b38
Autor:
Chiara Giorgi, Giorgia Lombardozzi, Fabrizio Ammannito, Marta Sofia Scenna, Eleonora Maceroni, Massimiliano Quintiliani, Michele d’Angelo, Annamaria Cimini, Vanessa Castelli
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 443 (2024)
Neurological disorders are the second cause of death and the leading cause of disability worldwide. Unfortunately, no cure exists for these disorders, but the actual therapies are only able to ameliorate people’s quality of life. Thus, there is an
Externí odkaz:
https://doaj.org/article/52e6e088356d4529ba7189b8014c39ef
Autor:
Andrea Aramini, Gianluca Bianchini, Samuele Lillini, Mara Tomassetti, Niccolò Pacchiarotti, Daniele Canestrari, Pasquale Cocchiaro, Rubina Novelli, Maria Concetta Dragani, Ferdinando Palmerio, Simone Mattioli, Simone Bordignon, Michele d’Angelo, Vanessa Castelli, Francesco d’Egidio, Sabatino Maione, Livio Luongo, Serena Boccella, Annamaria Cimini, Laura Brandolini, Michele Remo Chierotti, Marcello Allegretti
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 163, Iss , Pp 114845- (2023)
Chronic pain is an enormous public health concern, and its treatment is still an unmet medical need. Starting from data highlighting the promising effects of some nonsteroidal anti-inflammatory drugs in combination with gabapentin in pain treatment,
Externí odkaz:
https://doaj.org/article/e101ac01d4fc4c599d7e5d456b2c2125
Autor:
Laura Brandolini, Michele d’Angelo, Rubina Novelli, Vanessa Castelli, Cristina Giorgio, Anna Sirico, Pasquale Cocchiaro, Francesco D’Egidio, Elisabetta Benedetti, Claudia Cristiano, Antonella Bugatti, Anna Ruocco, Pier Giorgio Amendola, Carmine Talarico, Candida Manelfi, Daniela Iaconis, Andrea Beccari, Andreza U. Quadros, Thiago M. Cunha, Arnaldo Caruso, Roberto Russo, Annamaria Cimini, Andrea Aramini, Marcello Allegretti
Publikováno v:
Cell Death and Disease, Vol 13, Iss 5, Pp 1-15 (2022)
Abstract Chemotherapy-induced peripheral neuropathy (CIPN) and hypersensitivity reactions (HSRs) are among the most frequent and impairing side effects of the antineoplastic agent paclitaxel. Here, we demonstrated that paclitaxel can bind and activat
Externí odkaz:
https://doaj.org/article/482c74a958854186b399d4cb5817aa32
Autor:
Vanessa Castelli, Ivana Antonucci, Michele d'Angelo, Alessandra Tessitore, Veronica Zelli, Elisabetta Benedetti, Claudio Ferri, Giovambattista Desideri, Cesar Borlongan, Liborio Stuppia, Annamaria Cimini
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 2, Pp 251-266 (2021)
Abstract Stem cells offer the basis for the promotion of robust new therapeutic approaches for a variety of human disorders. There are still many limitations to be overcome before clinical therapeutic application, including a better understanding of
Externí odkaz:
https://doaj.org/article/15220a1f91ef4d6eb5ab0f6a993298c4