Výsledky vyhledávání - "Annamaria, Liguoro"

Akademický článek

RGDechi-hCit: αvβ3 selective pro-apoptotic peptide as potential carrier for drug delivery into melanoma metastatic cells.

Autor: Domenica Capasso, Ivan de Paola, Annamaria Liguoro, Annarita Del Gatto, Sonia Di Gaetano, Daniela Guarnieri, Michele Saviano, Laura Zaccaro

Publikováno v: PLoS ONE, Vol 9, Iss 9, p e106441 (2014)

αvβ3 integrin is an important tumor marker widely expressed on the surface of cancer cells. Recently, we reported some biological features of RGDechi-hCit, an αvβ3 selective peptide antagonist. In the present work, we mainly investigated the pro-

Externí odkaz: https://doaj.org/article/085f9945f6754adca3b570a8f6a8e92b

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Chemical Modification for Proteolytic Stabilization of the Selective αvβ3 Integrin RGDechi Peptide: in Vitro and in Vivo Activities on Malignant Melanoma Cells

Autor: Annamaria Liguoro, Daniela Comegna, Annarita Del Gatto, Antonella Zannetti, Sonia Di Gaetano, Ivan de Paola, Michele Saviano, Luigi Russo, Domenica Capasso, Laura Zaccaro

Publikováno v: Journal of medicinal chemistry 60 (2017): 9874–9884. doi:10.1021/acs.jmedchem.7b01590
info:cnr-pdr/source/autori:Comegna D.; Zannetti A.; Del Gatto A.; de Paola I.; Russo L.; Di Gaetano S.; Liguoro A.; Capasso D.; Saviano M.; Zaccaro L./titolo:Chemical Modification for Proteolytic Stabilization of the Selective alpha(v)beta(3) Integrin RGDechi Peptide: in Vitro and in Vivo Activities on Malignant Melanoma Cells/doi:10.1021%2Facs.jmedchem.7b01590/rivista:Journal of medicinal chemistry/anno:2017/pagina_da:9874/pagina_a:9884/intervallo_pagine:9874–9884/volume:60

Herein, we report the synthesis and biological characterization of the new peptide psi RGDechi as the first step toward novel targeted theranostics in melanoma. This pseudopeptide is designed from our previously reported RGDechi peptide, known to bin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ab6534123b25bab152e29b9cd897959
https://doi.org/10.1021/acs.jmedchem.7b01590

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Chemical Modification for Proteolytic Stabilization of the Selective α

Autor: Daniela, Comegna, Antonella, Zannetti, Annarita, Del Gatto, Ivan, de Paola, Luigi, Russo, Sonia, Di Gaetano, Annamaria, Liguoro, Domenica, Capasso, Michele, Saviano, Laura, Zaccaro

Publikováno v: Journal of medicinal chemistry. 60(23)

Herein, we report the synthesis and biological characterization of the new peptide ψRGDechi as the first step toward novel-targeted theranostics in melanoma. This pseudopeptide is designed from our previously reported RGDechi peptide, known to bind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ca874725f448ca4c9a322345d7c91f26
https://pubmed.ncbi.nlm.nih.gov/29144748

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Deciphering RGDechi peptide‐α 5 β 1 integrin interaction mode in isolated cell membranes

Autor: Roberto Fattorusso, Luigi Russo, Annamaria Liguoro, Sonia Di Gaetano, Laura Zaccaro, Biancamaria Farina, Michele Saviano, Domenica Capasso, Daniela Comegna, Gaetano Malgieri, Annarita Del Gatto

Publikováno v: Biopolymers
(2018). doi:10.1002/pep2.24065
info:cnr-pdr/source/autori:Russo L.; Farina B.; Del Gatto A.; Comegna D.; Di Gaetano S.; Capasso D.; Liguoro A.; Malgieri G.; Saviano M.; Fattorusso R.; Zaccaro L./titolo:Deciphering rgdechi peptide-?5?1integrin interaction mode in isolated cell membranes/doi:10.1002%2Fpep2.24065/rivista:Biopolymers (Print)/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume
Peptide Science 110 (2018): 1–14. doi:10.1002/pep2.24065
info:cnr-pdr/source/autori:Luigi Russo, Biancamaria Farina, Annarita Del Gatto, Daniela Comegna, Sonia Di Gaetano, Domenica Capasso, Annamaria Liguoro, Gaetano Malgieri, Michele Saviano, Roberto Fattorusso, Laura Zaccaro./titolo:Deciphering RGDechi peptide-a5b1 integrin interaction mode in isolated cell membranes/doi:10.1002%2Fpep2.24065/rivista:Peptide Science/anno:2018/pagina_da:1/pagina_a:14/intervallo_pagine:1–14/volume:110

Integrins are a large family of heterodimeric receptors critically engaged in pathological processes such as tumor progression and metastasis. Although they are validated therapeutic targets, the molecular determinants governing integrin-ligand inter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca6b5d75cfc72162d577734aed52258
https://doi.org/10.1002/pep2.24065

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TAZ is a coactivator for Pax8 and TTF-1, two transcription factors involved in thyroid differentiation

Autor: Barbara D'Andrea, Anna Mascia, Tina Di Palma, Annamaria Liguoro, Giovanna L. Liguori, Mariastella Zannini, Andrea Pappalardo, Tiziana de Cristofaro, Dolores Del Prete

Publikováno v: Experimental cell research 315 (2009): 162–175. doi:10.1016/j.yexcr.2008.10.016
info:cnr-pdr/source/autori:Di Palma T.; D'Andrea B.; Liguori G.L.; Liguoro A.; de Cristofaro T.; Del Prete D.; Pappalardo A.; Mascia A.; Zannini M./titolo:TAZ is a coactivator for Pax8 and TTF-1, two transcription factors involved in thyroid differentiation/doi:10.1016%2Fj.yexcr.2008.10.016/rivista:Experimental cell research/anno:2009/pagina_da:162/pagina_a:175/intervallo_pagine:162–175/volume:315

Pax8 and TTF-1 are transcription factors involved in the morphogenesis of the thyroid gland and in the transcriptional regulation of thyroid-specific genes. Both proteins are expressed in few tissues but their simultaneous presence occurs only in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e75e7ed71a7efa2bd2089a3179e8f3
https://doi.org/10.1016/j.yexcr.2008.10.016

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Cripto-independent Nodal signaling promotes positioning of the A–P axis in the early mouse embryo

Autor: Annamaria Liguoro, M. Graziella Persico, L. C. Goncalves, Ana Cristina Borges, José António Belo, Daniela D'Andrea, Ana Marisa Salgueiro, Giovanna L. Liguori

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Developmental biology
315 (2008): 280–289. doi:10.1016/j.ydbio.2007.12.027
info:cnr-pdr/source/autori:Liguori G.L.; Borges A.C.; D'Andrea D.; Liguoro A.; Goncalves L.; Salgueiro A.M.; Persico M.G.; Belo J.A./titolo:Cripto-independent Nodal signaling promotes positioning of the A-P axis in the early mouse embryo/doi:10.1016%2Fj.ydbio.2007.12.027/rivista:Developmental biology (Print)/anno:2008/pagina_da:280/pagina_a:289/intervallo_pagine:280–289/volume:315

During early mouse development, the TGF beta-related protein Nodal specifies the organizing centers that control the formation of the anterior-posterior (A-P) axis. EGF-CFC proteins are important components of the Nodal signaling pathway, most likely

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65a0b662f93c234e58d48e7212b2d0ef

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A Combined NMR and Computational Approach to Determine the RGDechi-hCit-alpha(v)beta(3) Integrin Recognition Mode in Isolated Cell Membranes

Autor: Domenica Capasso, Luigi Russo, Ivan de Paola, Biancamaria Farina, Laura Zaccaro, Michele Saviano, Annamaria Liguoro, Roberto Fattorusso, Sonia Di Gaetano, Paolo V. Pedone, Gaetano Malgieri, Annarita Del Gatto

Publikováno v: Chemistry (Weinh., Print) 22 (2016): 681–693. doi:10.1002/chem.201503126
info:cnr-pdr/source/autori:Farina, Biancamaria; de Paola, Ivan; Russo, Luigi; Capasso, Domenica; Liguoro, Annamaria; Del Gatto, Annarita; Saviano, Michele; Pedone, Paolo V.; Di Gaetano, Sonia; Malgieri, Gaetano; Zaccaro, Laura; Fattorusso, Roberto/titolo:A Combined NMR and Computational Approach to Determine the RGDechi-hCit-alpha(v)beta(3) Integrin Recognition Mode in Isolated Cell Membranes/doi:10.1002%2Fchem.201503126/rivista:Chemistry (Weinh., Print)/anno:2016/pagina_da:681/pagina_a:693/intervallo_pagine:681–693/volume:22

The critical role of integrins in tumor progression and metastasis has stimulated intense efforts to identify pharmacological agents that can modulate integrin function. In recent years, alpha(v)beta(3) and alpha(v)beta(5) integrin antagonists were d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35c51a952138fd8a2c1d8205349cc743

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The Fas/FasL system is a possible regulator of germ cell apoptosis in the testis of Torpedo marmorata

Autor: Annamaria Liguoro, Loredana Ricchiari, Piero Andreuccetti, Francesco Angelini, Marina Prisco

Publikováno v: Journal of Fish Biology. 69:1779-1787

The role played by the Fas/FasL system in the activation of apoptosis during the spermatogenesis of the spotted ray Torpedo marmorata was investigated. By immuno-histochemical and western blot techniques it was demonstrated that the Fas/FasL system i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6623dde8fc9fca2b12680856b5502a75
https://doi.org/10.1111/j.1095-8649.2006.01248.x

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Cadherin in developing and maturing cysts of Torpedo Marmorata Testis

Autor: Annamaria Liguoro, Marina Prisco, Loredana Ricchiari, Piero Andreuccetti, Francesco Angelini

Publikováno v: Molecular Reproduction and Development. 74:242-248

We investigated the presence of cadherins, Ca++ dependent cell–cell adhesion molecules, during the development and maturation of cysts in the testis of the spotted ray Torpedo marmorata. Using different anti-cadherin antibodies, we provide evidence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c6f7cb9854380898f8ae0b5be7586994
https://doi.org/10.1002/mrd.20517

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The nucleolus and its modifications during oogenesis of Torpedo marmorata

Autor: R. Montella, Marina Prisco, Annamaria Liguoro, Piero Andreuccetti, Loredana Ricchiari

Publikováno v: Journal of Fish Biology. 65:1489-1497

The structural organisation of the nucleolar apparatus during oogenesis of the spotted ray Torpedo marmorata was investigated. The observations showed that unlike other cartilaginous fishes, in T. marmorata the nucleolar apparatus was always represen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec9b5acd45f9183c1c07570774e91e77
https://doi.org/10.1111/j.0022-1112.2004.00539.x

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