Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Annamaria, Bevilacqua"'
Autor:
S. Dugnani, Angela Calastretti, Valeria Lucini, Gilberto Spadoni, Annamaria Bevilacqua, Gianfranco Canti, Marco Mor, Francesco Scaglione, Annalida Bedini, Silvia Rivara, Giuliana Gatti
Publikováno v:
Oncotarget
// Giuliana Gatti 1, * , Valeria Lucini 2, * , Silvana Dugnani 2 , Angela Calastretti 1 , Gilberto Spadoni 3 , Annalida Bedini 3 , Silvia Rivara 4 , Marco Mor 4 , Gianfranco Canti 1 , Francesco Scaglione 2 and Annamaria Bevilacqua 1 1 Department of M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31fb18afd5a42133059087de605be0b5
https://doi.org/10.18632/oncotarget.20124
https://doi.org/10.18632/oncotarget.20124
Autor:
Angela, Calastretti, Giuliana, Gatti, Valeria, Lucini, Silvana, Dugnani, Gianfranco, Canti, Francesco, Scaglione, Annamaria, Bevilacqua
Publikováno v:
International Journal of Molecular Sciences
Melatonin has been indicated as a possible oncostatic agent in different types of cancer, its antiproliferative role being demonstrated in several in vitro and in vivo experimental models of tumors. Specifically, melatonin was proven to inhibit cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c4d29ee10d28ca3ba3ed587e7f54f95c
https://pubmed.ncbi.nlm.nih.gov/29783631
https://pubmed.ncbi.nlm.nih.gov/29783631
Publikováno v:
The Prostate. 74:1411-1422
BACKGROUND The critical role of PTEN in regulating the PI3K/Akt/mTOR signaling pathway raises the possibility that targeting downstream effectors of the PI3K pathway, such as Bcl-2, might be an effective anti-proliferative strategy for PTEN-deficient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1513b87c29433ce413d001db3b6739bd
https://doi.org/10.1002/pros.22857
https://doi.org/10.1002/pros.22857
Autor:
Luciano Milanesi, Matteo Barcella, Roberta Alfieri, Ettore Mosca, Annamaria Bevilacqua, Gianfranco Canti
Publikováno v:
Biotechnology advances 30 (2012): 131–141. doi:10.1016/j.biotechadv.2011.08.004
info:cnr-pdr/source/autori:Mosca, Ettore; Barcella, Matteo; Alfieri, Roberta; Bevilacqua, Annamaria; Canti, Gianfranco; Milanesi, Luciano/titolo:Systems biology of the metabolic network regulated by the Akt pathway/doi:10.1016%2Fj.biotechadv.2011.08.004/rivista:Biotechnology advances/anno:2012/pagina_da:131/pagina_a:141/intervallo_pagine:131–141/volume:30
info:cnr-pdr/source/autori:Mosca, Ettore; Barcella, Matteo; Alfieri, Roberta; Bevilacqua, Annamaria; Canti, Gianfranco; Milanesi, Luciano/titolo:Systems biology of the metabolic network regulated by the Akt pathway/doi:10.1016%2Fj.biotechadv.2011.08.004/rivista:Biotechnology advances/anno:2012/pagina_da:131/pagina_a:141/intervallo_pagine:131–141/volume:30
Cancer has been proposed as an example of systems biology disease or network disease. Accordingly, tumor cells differ from their normal counterparts more in terms of intracellular network dynamics than single markers. Here we shall focus on a recentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ac7f0c01adb462c29f1cc942932a4ff
https://doi.org/10.1016/j.biotechadv.2011.08.004
https://doi.org/10.1016/j.biotechadv.2011.08.004
Publikováno v:
Cancer Research. 78:A052-A052
Prostate cancer is characterized by resistance to chemotherapy and is often associated with loss of the tumor suppressor PTEN, a negative regulator of the PI3K/AKT/mTOR pathway. Currently, taxanes are the first-line chemotherapy for advanced prostate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de7a0874e57886252067419978703836
https://doi.org/10.1158/1538-7445.prca2017-a052
https://doi.org/10.1158/1538-7445.prca2017-a052
Autor:
Federico Di Gesualdo, Matteo Lulli, Angelo Nicolin, Francesco Bertolini, Andrea Lapucci, Martino Donnini, Ewa Witort, Nicola Schiavone, Sergio Capaccioli, Gary Brewer, Laura Papucci, Annamaria Bevilacqua, Dominique Morello, Amedeo Amedei
Publikováno v:
The FASEB Journal. 24:1852-1865
The human antiapoptotic bcl-2 gene has been discovered in t(14;18) B-cell leukemias/lymphomas because of its overexpression caused at a transcriptional control level by the bcl-2/IgH fusion gene. We were the first to disclose the post-transcriptional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d3b8f4e479b9c6014a1715ac3d2101f
https://doi.org/10.1096/fj.09-140459
https://doi.org/10.1096/fj.09-140459
Autor:
Andrea Lapucci, Angelo Nicolin, Laura Ghisolfi, Sergio Capaccioli, Gianfranco Canti, Nicola Schiavone, Laura Papucci, Giuseppe Tataranni, Annamaria Bevilacqua
Publikováno v:
Molecular Pharmacology. 68:816-821
RNA has become a promising target for pharmacological purposes. Most current strategies are directed toward down-regulating its functions. In this study, we provide evidence of the up-regulation of messenger RNA in a sequence-specific manner. The bcl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd60a2488f19cc45eead45c52670a16
https://doi.org/10.1124/mol.105.014357
https://doi.org/10.1124/mol.105.014357
Publikováno v:
Journal of Cellular Physiology. 195:356-372
Recent evidence suggests that gene expression may be regulated, at least in part, at post-transcriptional level by factors inducing the extremely rapid degradation of messenger RNAs. These factors include reactions between adenyl-uridyl-rich elements
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915197280da37c35ac1d4842880a46f8
https://doi.org/10.1002/jcp.10272
https://doi.org/10.1002/jcp.10272
Publikováno v:
The Prostate. 74(14)
The critical role of PTEN in regulating the PI3K/Akt/mTOR signaling pathway raises the possibility that targeting downstream effectors of the PI3K pathway, such as Bcl-2, might be an effective anti-proliferative strategy for PTEN-deficient prostate c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6e3548fb05e2cf33d39e6f34b982f890
https://pubmed.ncbi.nlm.nih.gov/25111376
https://pubmed.ncbi.nlm.nih.gov/25111376
Autor:
Annamaria Bevilacqua, Luciano Milanesi, Gianfranco Canti, Carlo Maj, Roberta Alfieri, Ettore Mosca
Publikováno v:
Frontiers in Physiology, Vol 3 (2012)
Frontiers in Physiology
Frontiers in physiology 3 (2012): 418. doi:10.3389/fphys.2012.00418
info:cnr-pdr/source/autori:Mosca, Ettore; Alfieri, Roberta; Maj, Carlo; Bevilacqua, Annamaria; Canti, Gianfranco; Milanesi, Luciano/titolo:Computational modeling of the metabolic States regulated by the kinase akt./doi:10.3389%2Ffphys.2012.00418/rivista:Frontiers in physiology/anno:2012/pagina_da:418/pagina_a:/intervallo_pagine:418/volume:3
Frontiers in Physiology
Frontiers in physiology 3 (2012): 418. doi:10.3389/fphys.2012.00418
info:cnr-pdr/source/autori:Mosca, Ettore; Alfieri, Roberta; Maj, Carlo; Bevilacqua, Annamaria; Canti, Gianfranco; Milanesi, Luciano/titolo:Computational modeling of the metabolic States regulated by the kinase akt./doi:10.3389%2Ffphys.2012.00418/rivista:Frontiers in physiology/anno:2012/pagina_da:418/pagina_a:/intervallo_pagine:418/volume:3
Signal transduction pathways and gene regulation determine a major reorganization of metabolic activities in order to support cell proliferation. Protein Kinase B (PKB), also known as Akt, participates in the PI3K/Akt/mTOR pathway, a master regulator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f96d2f76f3a5507ec8274b6c76af14e7