Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Annalise Di Marco"'
Autor:
Maria Rosaria Battista, Antonella Grigoletto, Tommaso Tedeschini, Antonella Cellucci, Fabrizio Colaceci, Ralph Laufer, Gianfranco Pasut, Annalise Di Marco
Publikováno v:
PLoS ONE, Vol 17, Iss 3 (2022)
Ciliary neurotrophic factor (CNTF) is a neurotrophic cytokine able to induce appetite reduction, weight loss and antidiabetic effects. However, its susceptibility to neutralizing anti-CNTF antibodies in patients hampered its use for treatment of huma
Externí odkaz:
https://doaj.org/article/275712289d7d46749feca52a20c48f5e
Autor:
Esther Torrente, Valentina Fodale, Alina Ciammaichella, Federica Ferrigno, Jesus M. Ontoria, Simona Ponzi, Ilaria Rossetti, Alessio Sferrazza, Jérôme Amaudrut, Antonino Missineo, Simone Esposito, Simone Palombo, Martina Nibbio, Mauro Cerretani, Monica Bisbocci, Antonella Cellucci, Annalise di Marco, Cristina Alli, Vincenzo Pucci, Carlo Toniatti, Alessia Petrocchi
Publikováno v:
ACS Medicinal Chemistry Letters. 14:156-162
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6897f93fa03f3115ac19fe47da452c3
https://doi.org/10.1021/acsmedchemlett.2c00454
https://doi.org/10.1021/acsmedchemlett.2c00454
Autor:
Annalise Di Marco, Domenico Vignone, Odalys Gonzalez Paz, Ivan Fini, Maria Rosaria Battista, Antonella Cellucci, Elena Bracacel, Giulio Auciello, Maria Veneziano, Vinod Khetarpal, Mark Rose, Alessandro Rosa, Isabelle Gloaguen, Edith Monteagudo, Todd Herbst, Celia Dominguez, Ignacio Muñoz-Sanjuán
Publikováno v:
Cells, Vol 9, Iss 4, p 994 (2020)
The blood-brain barrier (BBB) is responsible for the homeostasis between the cerebral vasculature and the brain and it has a key role in regulating the influx and efflux of substances, in healthy and diseased states. Stem cell technology offers the o
Externí odkaz:
https://doaj.org/article/d4344a862cc142e2914339bfced09308
Autor:
Daniel Elbaum, Maria G Beconi, Edith Monteagudo, Annalise Di Marco, Maria S Quinton, Kathryn A Lyons, Andrew Vaino, Steven Harper
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0192028 (2018)
In cells, phosphorylation of pantothenic acid to generate phosphopantothenic acid by the pantothenate kinase enzymes is the first step in coenzyme A synthesis. Pantothenate kinase 2, the isoform localized in neuronal cell mitochondria, is dysfunction
Externí odkaz:
https://doaj.org/article/c07328031f9c40e7ac21d7d5ae98a063
Autor:
Domenico Vignone, Odalys Gonzalez Paz, Ivan Fini, Antonella Cellucci, Giulio Auciello, Maria Rosaria Battista, Isabelle Gloaguen, Silvia Fortuni, Cristina Cariulo, Vinod Khetarpal, Celia Dominguez, Ignacio Muñoz-Sanjuán, Annalise Di Marco
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 14; Pages: 7813
While blood–brain barrier (BBB) dysfunction has been described in neurological disorders, including Huntington’s disease (HD), it is not known if endothelial cells themselves are functionally compromised when promoting BBB dysfunction. Furthermor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a55c902a855245c8bcc46415b9585329
Autor:
Adina Borbély, Eduard Figueras, Ana Martins, Simone Esposito, Giulio Auciello, Edith Monteagudo, Annalise Di Marco, Vincenzo Summa, Paola Cordella, Raffaella Perego, Isabell Kemker, Marcel Frese, Paola Gallinari, Christian Steinkühler, Norbert Sewald
Publikováno v:
Pharmaceutics, Vol 11, Iss 4, p 151 (2019)
Cryptophycins are potent tubulin polymerization inhibitors with picomolar antiproliferative potency in vitro and activity against multidrug-resistant (MDR) cancer cells. Because of neurotoxic side effects and limited efficacy in vivo, cryptophycin-52
Externí odkaz:
https://doaj.org/article/8e55442c453b47dfb515e3a4632fb51a
Autor:
Daniel Elbaum, Daniel O. Cicero, Paola Fezzardi, Annalise Di Marco, Steven J. Harper, Savina Malancona, Elena Bracacel, Andrea Vecchi, Ilaria Rossetti, Edith Monteagudo, Alina Ciammaichella, Giulio Auciello, Odalys Gonzalez Paz, Maria G. Beconi
Publikováno v:
Journal of Medicinal Chemistry. 63:15785-15801
Mutations in the human PANK2 gene are implicated in neurodegenerative diseases such as pantothenate kinase-associated neurodegeneration (PKAN) and result in low levels of coenzyme-A (CoA) in the CNS due to impaired production of phosphopantothenic ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c53c5a490a956c7c2db428b0dc609e43
https://doi.org/10.1021/acs.jmedchem.0c01531
https://doi.org/10.1021/acs.jmedchem.0c01531
Autor:
Maria Rosaria Battista, Rajhans Sharma, Yves Mély, Marisabella Santoriello, Edith Monteagudo, Paola Fezzardi, Eleonore Real, Maurizio Zazzi, Vincenzo Summa, Mattia Mori, Maria Chiara Dasso Lang, Steven J. Harper, Savina Malancona, Antonella Cellucci, Manuel Pires, Martina Nibbio, Maurizio Botta, Roberto Speziale, Andreina Basta, Nadia Gennari, Francesco Saladini, Davide De Forni, Annalise Di Marco, Alessia Giannini, Lesia Kovalenko
Publikováno v:
ACS Med Chem Lett
[Image: see text] The HIV-1 nucleocapsid (NC) protein is a small basic DNA and RNA binding protein that is absolutely necessary for viral replication and thus represents a target of great interest to develop new anti-HIV agents. Moreover, the highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bca7f5ccee8b2fa882bee58c45c157f
https://doi.org/10.1021/acsmedchemlett.9b00608
https://doi.org/10.1021/acsmedchemlett.9b00608
Autor:
Maria Rosaria Battista, Antonella Grigoletto, Tommaso Tedeschini, Antonella Cellucci, Fabrizio Colaceci, Ralph Laufer, Gianfranco Pasut, Annalise Di Marco
Publikováno v:
PloS one. 17(3)
Ciliary neurotrophic factor (CNTF) is a neurotrophic cytokine able to induce appetite reduction, weight loss and antidiabetic effects. However, its susceptibility to neutralizing anti-CNTF antibodies in patients hampered its use for treatment of huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18984018e339d77e1a28aa1365875f54
https://pubmed.ncbi.nlm.nih.gov/35316287
https://pubmed.ncbi.nlm.nih.gov/35316287
Autor:
Mark Rose, Odalys Gonzalez Paz, Giulio Auciello, Annalise Di Marco, Todd Herbst, Ignacio Muñoz-Sanjuán, Domenico Vignone, Edith Monteagudo, Vinod Khetarpal, Matteo Zini, Maria Rosaria Battista, Laura Orsatti, Vincenzo Summa, Celia Dominguez, Leticia M Toledo-Sherman, Ivan Fini, Antonella Cellucci
Publikováno v:
Molecular Pharmaceutics. 16:2069-2082
Huntington's disease (HD) is a neurodegenerative disease caused by polyglutamine expansion in the huntingtin protein. For drug candidates targeting HD, the ability to cross the blood-brain barrier (BBB) and reach the site of action in the central ner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27cfdbc702df6685a64c4f15855675c2
https://doi.org/10.1021/acs.molpharmaceut.9b00042
https://doi.org/10.1021/acs.molpharmaceut.9b00042