Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Annalisa Zunino"'
Autor:
Stefano Vagge, Donatella Vecchio, Renzo Corvò, Antonio Daga, Carlo Emanuele Neumaier, Alessandro Poggi, Gabriella Baio, Alessandro Raso, Jean Louis Ravetti, Samantha Mascelli, Daniela Marubbi, Annalisa Zunino, Elisa Carra, Maria Pia Brisigotti, Guido Frosina
Publikováno v:
International Journal of Cancer. 135:479-491
We have previously shown that pharmacological inhibition of ataxia telangiectasia mutated (ATM) protein sensitizes glioblastoma-initiating cells (GICs) to ionizing radiation (IR). Herein, we report the experimental conditions to overcome GIC radiores
Autor:
M.G. Grimoldi, Eugenio Erba, Annalisa Zunino, Maria Teresa Bardella, Luisa Doneda, Elena Dogliotti, Luca Elli, Silvia Viaggi, Leda Roncoroni
Publikováno v:
Cancer Investigation. 28:7-12
The aim of the study was to investigate whether changes in the pattern of gene copy number and cell cycle were present passing from the two- to the three-dimensional cell culture system. We used three human colon adenocarcinoma cell lines grown two-
Autor:
Annalisa Zunino, Edoardo Rossi, Silvia Viaggi, Mauro Spriano, Laura Ottaggio, Irena Maric, Alessia Grozio
Publikováno v:
Hematological Oncology. 26:39-42
Chromosome aberrations are frequently found in B-cell chronic lymphocytic leukaemia (B-CLL), and specific chromosome aberrations identify poor prognostic subgroups. Almost all the aberrations identified in B-CLL involve loci where genes with a role i
Autor:
Paolo Degan, Federico Cesarone, Proto Pippia, Annalisa Zunino, Silvia Viaggi, Angelo Abbondandolo, Laura Ottaggio, Monica Sancandi, Grazia Galleri
Publikováno v:
Journal of Cellular Biochemistry. 94:460-469
Exposure of freshly drawn lymphocytes and lymphoblastoid cells (LB and COR3) to simulated microgravity decreased the intracellular ATP concentration to 50%-40% of the value found in normal growth conditions. The decrease was reversible although recov
Autor:
Angelo Abbondandolo, Massimo Carbone, Silvia Viaggi, Annalisa Zunino, Mario Sessarego, Laura Ottaggio, Simona Zupo
Publikováno v:
Cancer Genetics and Cytogenetics. 148:133-136
The majority of splenic marginal zone lymphoma (SMZL) patients experience an indolent clinical course; however, some cases transform to a high-grade lymphoma. Cytogenetic analyses have shown that chromosome 7 is the most frequently altered chromosome
Publikováno v:
Environmental and Molecular Mutagenesis. 29:152-160
Rodent UV-sensitive mutant cell lines of complementation groups 6 and 8 are the genetic counterparts of human Cockayne syndrome CS-B and CS-A, respectively. The original mutant in this group, UV61, was described as defective in cyclobutane pyrimidine
Publikováno v:
BMC Cancer
BMC Cancer, Vol 10, Iss 1, p 54 (2010)
BMC Cancer, Vol 10, Iss 1, p 54 (2010)
Background Malignant pleural mesothelioma is a rare disease known to be resistant to conventional therapies. A better understanding of mesothelioma biology may provide the rationale for new therapeutic strategies. In this regard, tumor cell lines dev
Autor:
Renato Spaziante, Giorgio Corte, Gianluigi Casartelli, Enrico Cappelli, Mara Foresta, Monica Ropolo, Gianluigi Zona, Fabrizio Griffero, Guido Frosina, Antonio Daga, Alessandro Poggi, Annalisa Zunino
Publikováno v:
Molecular cancer research : MCR. 7(3)
It has been reported that cancer stem cells may contribute to glioma radioresistance through preferential activation of the DNA damage checkpoint response and an increase in DNA repair capacity. We have examined DNA repair in five stem and nonstem gl
Autor:
Laura, Ottaggio, Silvia, Viaggi, Annalisa, Zunino, Simona, Zupo, Edoardo, Rossi, Mauro, Spriano, Angelo, Abbondandolo, Manlio, Ferrarini
Publikováno v:
Haematologica. 88(7)
B-cell chronic lymphocytic leukemia (B-CLL) results from the accumulation of monoclonal CD5+ B cells. Despite its homogeneity at cellular level, B-CLL is clinically heterogeneous. Clinical studies indicate that CD38+ B-CLL are characterized by a more
Autor:
Ulrich Pfeffer, Giovanna Angelini, Alessia Isabella Esposito, Simonetta Astigiano, Annalisa Zunino, Walter Giaretti, Adriana Amaro, Valentina Mirisola, Massimiliano Maffei, Maurizio Viale
Publikováno v:
Cancer Research. 72:496-496
The acquisition of an invasive phenotype is a pre-requisite for metastasis. We set out to develop cellular systems that can mirror transient and stbale molecular alterations that confer an invasive phenotype to breast cancer cells. We observed that i