Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Annalisa Mercuri"'
Autor:
Nikoletta Fotaki, Annalisa Mercuri
Publikováno v:
#N# In Vitro Drug Release Testing of Special Dosage Forms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7860e4e43c68f5581343a8bba96f5fb1
https://doi.org/10.1002/9781118675748.ch5
https://doi.org/10.1002/9781118675748.ch5
Publikováno v:
TU Graz
Self-emulsifying drug delivery systems (SEDDS), often intended for oral delivery, are normally explored in biorelevant aqueous media. The high complexity of these multi-component systems leaves the understanding of self-emulsification poor, hindering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a53d16070627966909ca40b1a53450e
https://doi.org/10.1208/s12249-017-0785-2
https://doi.org/10.1208/s12249-017-0785-2
Publikováno v:
Mercuri, A, Pagliari, M, Baxevanis, F, Fares, R & Fotaki, N 2017, ' Understanding and predicting the impact of critical dissolution variables for nifedipine immediate release capsules by multivariate data analysis ', International Journal of Pharmaceutics, vol. 518, no. 1-2, pp. 41-49 . https://doi.org/10.1016/j.ijpharm.2016.12.034
In this study the selection of in vivo predictive in vitro dissolution experimental set-ups using a multivariate analysis approach, in line with the Quality by Design (QbD) principles, is explored. The dissolution variables selected using a design of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a77b933d639da69d664370556b7a2a
https://doi.org/10.1016/j.ijpharm.2016.12.034
https://doi.org/10.1016/j.ijpharm.2016.12.034
Autor:
Stefan Mohr, Eleonore Fröhlich, Sandra Stranzinger, Shengqian Wu, Sharareh Salar-Behzadi, Annalisa Mercuri, Massimo Bresciani
Publikováno v:
International Journal of Pharmaceutics. 515:271-280
This work aims to better understand the in vivo behaviour of modified release (MR) formulations (Envarsus® tablets and Advagraf® capsules) using in vitro properties of tacrolimus and in silico simulations. The in silico concentration profiles of ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74bccda1a003c41e266d9b47147b9e45
https://doi.org/10.1016/j.ijpharm.2016.10.020
https://doi.org/10.1016/j.ijpharm.2016.10.020
Autor:
Carole Planchette, István Kondor, Georg Scharrer, Helfried Steiner, Günter Brenn, Annalisa Mercuri
Publikováno v:
International Journal of Heat and Mass Transfer. 92:558-571
A one-dimensional theoretical model for the non-isothermal drying of particle-laden pastes on solid substrates is developed and solutions of the model transport equations for the mass fractions of the liquid mixture components, the particle volume fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c43c39bb48c7a37d4d676eff01569e9e
https://doi.org/10.1016/j.ijheatmasstransfer.2015.09.007
https://doi.org/10.1016/j.ijheatmasstransfer.2015.09.007
Publikováno v:
Frontiers in Pharmacology
Modern strategies in drug development employ in silico techniques in the design of compounds as well as estimations of pharmacokinetics, pharmacodynamics and toxicity parameters. The quality of the results depends on software algorithm, data library
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::116858949ad697b0c8a829be17ee6803
https://doi.org/10.3389/fphar.2016.00181
https://doi.org/10.3389/fphar.2016.00181
Autor:
Annalisa Mercuri, Massimo Bresciani, Shengqian Wu, Sharareh Salar-Behzadi, Sarah Zellnitz, Eleonore Fröhlich
Publikováno v:
International journal of pharmaceutics. 513(1-2)
In silico modeling was used to predict the impact of carrier surface modifications on the in vivo plasma concentration of an active pharmaceutical ingredient (API) and as a tool to support formulation development. In vitro fine particle fraction (FPF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b1de5a717c9fecc15ad27eaca58dbcb
https://pubmed.ncbi.nlm.nih.gov/27592196
https://pubmed.ncbi.nlm.nih.gov/27592196
Publikováno v:
Mercuri, A, Fares, R, Bresciani, M & Fotaki, N 2016, ' An in vitro-in vivo correlation study for nifedipine immediate release capsules administered with water, alcoholic and non-alcoholic beverages : Impact of in vitro dissolution media and hydrodynamics ', International Journal of Pharmaceutics, vol. 499, no. 1-2, pp. 330-342 . https://doi.org/10.1016/j.ijpharm.2015.12.047
The impact of hydrodynamics and media composition on nifedipine dissolution profile from IR (immediate release) soft capsules was investigated using dissolution apparatus USP1, USP2, USP3 and USP4 (United State Pharmacopoeia). Media composition was v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::289a40b5064d89f5ac3aa6221628ee16
https://purehost.bath.ac.uk/ws/files/139322857/Mercuri_et_al_IJP.pdf
https://purehost.bath.ac.uk/ws/files/139322857/Mercuri_et_al_IJP.pdf
Autor:
Annalisa Mercuri Mercuri
Publikováno v:
Current drug delivery. 13(8)
Background Quality by Design (QbD) is an approach encouraged by regulatory bodies and applied by pharmaceutical industries to improve the quality of the final product. The objective of this paper is to describe via a QbD approach the available knowle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14726702e143ecf689a72ce03aa11ec8
https://pubmed.ncbi.nlm.nih.gov/27012669
https://pubmed.ncbi.nlm.nih.gov/27012669
Publikováno v:
International Journal of Pharmaceutics. 298:164-175
Differences in the dynamics of powder densification between eccentric and rotary machine were pointed out by compressing at different compression pressures microcrystalline cellulose, lactose monohydrate and dicalcium phosphate dihydrate and recoveri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65a63740bd67bc1766e0f8fa4e2aabfd
https://doi.org/10.1016/j.ijpharm.2005.04.033
https://doi.org/10.1016/j.ijpharm.2005.04.033