Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Annalisa DiRuscio"'
Autor:
Min Ye, Irene Lowers, Martin Balastik, Roberto Avellino, Meritxell Alberich-Jorda, Annalisa DiRuscio, Ruud Delwel, Hanna S. Radomska, Hong Zhang, Clara Shapiro-Koss, Alexander K. Ebralidze, Giovanni Amabile, Ari Melnick, Junyan Zhang, Daniel G. Tenen, Peter J. M. Valk, Bas J. Wouters, Maria E. Figueroa
Publikováno v:
Journal of Clinical Investigation, 122(12), 4490-4504. The American Society for Clinical Investigation
C/EBPs are a family of transcription factors that regulate growth. control and differentiation of various tissues. We found that C/EBP gamma is highly upregulated in a subset of acute Myeloid leukemia (AML) samples characterized by C/EBP alpha hyperm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdf8db86a523096eb7dca9fc521a7e71
https://hdl.handle.net/1765/60889
https://hdl.handle.net/1765/60889
Autor:
David T. Scadden, Annalisa DiRuscio, Elena Levantini, Junyan Zhang, Daniel G. Tenen, Philipp B. Staber, Alexander K. Ebralidze, Claus Nerlov, Hong Zhang, Henry Yang, Meritxell Alberich-Jorda, Borja Saez, Giovanni Amabile, Min Ye, Véronique Lefebvre, Maarten Hoogenkamp, Peter J. M. Valk, Ruud Delwel, Jörg Cammenga, Robert S. Welner, Constanze Bonifer
Publikováno v:
Cancer Cell, 24(5), 575-588. Cell Press
Mutation or epigenetic silencing of the transcription factor C/EBP alpha is observed in similar to 10% of patients with acute myeloid leukemia (AML). In both cases, a common global gene expression profile is observed, but downstream targets relevant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cde3de0146fedd738e76b51acab23cf9
https://pubmed.ncbi.nlm.nih.gov/24229703
https://pubmed.ncbi.nlm.nih.gov/24229703
Autor:
Mark T. Bedford, Annalisa DiRuscio, Daniel G. Tenen, Manoj Bhasin, Elena Levantini, Karen B. O'Brien, Natasha J. Sng, Meritxell Alberich-Jorda, Tyler Caron, Gang Huang, Ulrich Steidl, Neelu Yadav, Alexander K. Ebralidze, Daehoon Kim, Scott J. Rodig, Balazs Halmos, Olivier Kocher, Susumu Kobayashi
Coactivator-associated arginine methyltransferase I (CARM1; PRMT4) regulates gene expression by multiple mechanisms including methylation of histones and coactivation of steroid receptor transcription. Mice lacking CARM1 are small, fail to breathe an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b3a0df96dd96943434c5f61da1119a3
https://europepmc.org/articles/PMC2882134/
https://europepmc.org/articles/PMC2882134/
Reduced BRCA1 expression due to promoter hypermethylation in therapy-related acute myeloid leukaemia
Autor:
Francesco D'Alo', Marcella Zollino, Luigi Maria Larocca, Alessandra Scardocci, Giuseppe Leone, Daniela Gumiero, Annalisa Diruscio, Maria Teresa Voso, Stefan Hohaus, Emiliano Fabiani, Maurizio Martini, Francesco Guidi
Publikováno v:
British Journal of Cancer
BRCA1 plays a pivotal role in the repair of DNA damage, especially following chemotherapy and ionising radiation. We were interested in the regulation of BRCA1 expression in acute myeloid leukaemia (AML), in particular in therapy-related forms (t-AML
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6358bc6c09f9e98b6e5c5495c2c41a3
https://pubmed.ncbi.nlm.nih.gov/17047656
https://pubmed.ncbi.nlm.nih.gov/17047656
Autor:
Philipp B. Staber, Daniel G. Tenen, Pu Zhang, Annalisa DiRuscio, Min Ye, Boris Bartholdy, Gang Huang, Alexander K. Ebralidze
Publikováno v:
Web of Science
Abstract 1468 Poster Board I-491 Background: Levels of the Ets transcription factor PU.1 control normal hematopoietic differentiation and even modest alterations can lead to leukemia and lymphoma. Regulation of PU.1 levels at different stages of hema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8404426c43a287e3cc18dfce51af3021
https://doi.org/10.1182/blood.v114.22.1468.1468
https://doi.org/10.1182/blood.v114.22.1468.1468
Autor:
Alex Ebralidze, Pu Zhang, Junyan Zhang, Daniel G. Tenen, Elena Levantini, Chris Hetherington, Annalisa DiRuscio, Gang Huang
Publikováno v:
Blood. 112:594-594
The level of expression of the transcription factor PU.1 is a critical determinant of lineage commitment in normal hematopoiesis, and dysregulation of PU.1 leads to development of leukemia. In mice with targeted disruption of the PU.1 upstream regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ff2758250ec40cdaf0a849162a9a47a
https://doi.org/10.1182/blood.v112.11.594.594
https://doi.org/10.1182/blood.v112.11.594.594