Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Annalisa Cabriolu"'
Autor:
Stefania Satta, Lucia Perseu, Paolo Moi, Isadora Asunis, Annalisa Cabriolu, Liliana Maccioni, Franca Rosa Demartis, Laura Manunza, Antonio Cao, Renzo Galanello
Publikováno v:
Haematologica, Vol 96, Iss 5 (2011)
The persistence of high fetal hemoglobin level in adults may ameliorate the clinical phenotype of beta-thalassemia and sickle cell anemia. Several genetic variants responsible for hereditary persistence of fetal hemoglobin, linked and not linked to t
Externí odkaz:
https://doaj.org/article/ddb2d457f7d14a08a46e112c95e16adb
Autor:
Sjoukje J. C. van der Stegen, Pieter L. Lindenbergh, Roseanna M. Petrovic, Hongyao Xie, Mame P. Diop, Vera Alexeeva, Yuzhe Shi, Jorge Mansilla-Soto, Mohamad Hamieh, Justin Eyquem, Annalisa Cabriolu, Xiuyan Wang, Ramzey Abujarour, Tom Lee, Raedun Clarke, Bahram Valamehr, Maria Themeli, Isabelle Riviere, Michel Sadelain
Publikováno v:
van der Stegen, S J C, Lindenbergh, P L, Petrovic, R M, Xie, H, Diop, M P, Alexeeva, V, Shi, Y, Mansilla-Soto, J, Hamieh, M, Eyquem, J, Cabriolu, A, Wang, X, Abujarour, R, Lee, T, Clarke, R, Valamehr, B, Themeli, M, Riviere, I & Sadelain, M 2022, ' Generation of T-cell-receptor-negative CD8αβ-positive CAR T cells from T-cell-derived induced pluripotent stem cells ', Nature Biomedical Engineering, vol. 6, no. 11, pp. 1284-1297 . https://doi.org/10.1038/s41551-022-00915-0
Nature Biomedical Engineering, 6(11), 1284-1297. Nature Publishing Group
Nat Biomed Eng
Nature Biomedical Engineering, 6(11), 1284-1297. Nature Publishing Group
Nat Biomed Eng
The production of autologous T cells expressing a chimaeric antigen receptor (CAR) is time-consuming, costly and occasionally unsuccessful. T-cell-derived induced pluripotent stem cells (TiPS) are a promising source for the generation of ‘off-the-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b154e71865ba41f6af9d0b1d675890f
https://doi.org/10.1038/s41551-022-00915-0
https://doi.org/10.1038/s41551-022-00915-0
Autor:
Annalisa Cabriolu, Ashlesha Odak, Lee Zamparo, Han Yuan, Christina S. Leslie, Michel Sadelain
Publikováno v:
Molecular Therapy. 30:2199-2209
The globin genes are archetypal tissue-specific genes that are silent in most tissues but for late-stage erythroblasts upon terminal erythroid differentiation. The transcriptional activation of the β-globin gene is under the control of proximal and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::283df51df24b5691b6e146be92157f6b
https://doi.org/10.1016/j.ymthe.2022.02.028
https://doi.org/10.1016/j.ymthe.2022.02.028
Autor:
Farid Boulad, Aurelio Maggio, Xiuyan Wang, Paolo Moi, Santina Acuto, Friederike Kogel, Chayamon Takpradit, Susan Prockop, Jorge Mansilla-Soto, Annalisa Cabriolu, Ashlesha Odak, Jinrong Qu, Keyur Thummar, Fang Du, Lingbo Shen, Simona Raso, Rita Barone, Rosario Di Maggio, Lorella Pitrolo, Antonino Giambona, Maura Mingoia, John K. Everett, Pascha Hokama, Aoife M. Roche, Vito Adrian Cantu, Hriju Adhikari, Shantan Reddy, Eric Bouhassira, Narla Mohandas, Frederic D. Bushman, Isabelle Rivière, Michel Sadelain
Publikováno v:
Nature Medicine. 28:63-70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86a418ea0bb1cd29c0f5b7c1c84f95fd
https://doi.org/10.1038/s41591-021-01554-9
https://doi.org/10.1038/s41591-021-01554-9
Autor:
Jiaming Wang, M Franca Marongiu, Maura Mingoia, Laura Manunza, Isadora Asunis, M. Giuseppina Marini, Yuet Wai Kan, Yukio Nakamura, Annalisa Cabriolu, Paolo Moi, Cristian Antonio Caria, Francesco Cucca, Lin Ye, Ryo Kurita, M Carla Sollaino
Publikováno v:
British Journal of Haematology. 192:395-404
Hereditary persistence of fetal haemoglobin (HPFH) is the major modifier of the clinical severity of β-thalassaemia. The homozygous mutation c.-196 C>T in the Aγ-globin (HBG1) promoter, which causes Sardinian δβ0 -thalassaemia, is able to complet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25570a076b4a3fd13c7ff90b74b570e4
https://doi.org/10.1111/bjh.17167
https://doi.org/10.1111/bjh.17167
Autor:
Michel Sadelain, Jie Sun, Judith Feucht, Annalisa Cabriolu, Josef Leibold, Anton Dobrin, Zeguo Zhao, Yu-Jui Ho, Justin Eyquem, Mohamad Hamieh
Publikováno v:
Nature Medicine. 25:82-88
Chimeric antigen receptors (CARs) are synthetic receptors that target and reprogram T cells to acquire augmented antitumor properties1. CD19-specific CARs that comprise CD28 and CD3ζ signaling motifs2 have induced remarkable responses in patients wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c4eab2752596ff1198db83ce3f2beeb
https://doi.org/10.1038/s41591-018-0290-5
https://doi.org/10.1038/s41591-018-0290-5
Autor:
Maura, Mingoia, Cristian A, Caria, Lin, Ye, Isadora, Asunis, M Franca, Marongiu, Laura, Manunza, M Carla, Sollaino, Jiaming, Wang, Annalisa, Cabriolu, Ryo, Kurita, Yukio, Nakamura, Francesco, Cucca, Yuet W, Kan, M Giuseppina, Marini, Paolo, Moi
Publikováno v:
British journal of haematologyReferences. 192(2)
Hereditary persistence of fetal haemoglobin (HPFH) is the major modifier of the clinical severity of β-thalassaemia. The homozygous mutation c.-196 CT in the Aγ-globin (HBG1) promoter, which causes Sardinian δβ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a8e4b16955645de8560b0a91220a72f2
https://pubmed.ncbi.nlm.nih.gov/33216968
https://pubmed.ncbi.nlm.nih.gov/33216968
Publikováno v:
Blood. 136:29-29
The beta-thalassemias and sickle cell disease are the most common monogenic inherited blood disorders, both arising from mutations affecting the beta-globin locus. Recent clinical trials utilizing lentiviral-mediated beta-globin gene transfer in auto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::051e87a90542daa93b9fff0b3748b222
https://doi.org/10.1182/blood-2020-142989
https://doi.org/10.1182/blood-2020-142989
Publikováno v:
Hematology/oncology clinics of North America. 32(2)
The β-thalassemias are inherited blood disorders that result from insufficient production of the β-chain of hemoglobin. More than 200 different mutations have been identified. β-Thalassemia major requires life-long transfusions. The only cure for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::991cdc29e18f88c886fffdb210f1392c
https://pubmed.ncbi.nlm.nih.gov/29729789
https://pubmed.ncbi.nlm.nih.gov/29729789
Autor:
Michel Sadelain, Jie Sun, Judith Feucht, Yu-Jui Ho, Mohamad Hamieh, Anton Dobrin, Justin Eyquem, Annalisa Cabriolu, Zeguo Zhao, Josef Leibold
Publikováno v:
Nature Medicine. 25:530-530
In the version of this article originally published, there was an error in the legend for Extended Data Fig. 7. The legend for panel f was originally: "f, FACS analysis of IL7R-, CD62L- and CD45RA- expression on TRAC-1928ζ and TRAC-1XX CAR T cells a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::675c89d71b6e26bf34c072e1a6f5318e
https://doi.org/10.1038/s41591-019-0360-3
https://doi.org/10.1038/s41591-019-0360-3