Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Annalisa Bianco"'
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Unconjugated bilirubin (UCB) is more than the final product of heme catabolism. Mildly elevated systemic bilirubin concentrations, such as in Gilbert syndrome (GS), protect against various oxidative stress-mediated and metabolic diseases,
Externí odkaz:
https://doaj.org/article/26f2a8cd30174acbaec6be4634cbf4ac
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 696 (2022)
Bilirubin has been regarded as a powerful endogenous antioxidant and anti-inflammatory molecule, able to act on cellular pathways as a hormone. Diabetic kidney disease (DKD) is a common chronic complication of diabetes, and it is the leading cause of
Externí odkaz:
https://doaj.org/article/e9c43202850845df8b56e8b7630dff4c
Autor:
Cristina Cheroni, Lorena Donnici, Alessio Aghemo, Francesca Balistreri, Annalisa Bianco, Valeria Zanoni, Massimiliano Pagani, Roberta Soffredini, Roberta D'Ambrosio, Maria Grazia Rumi, Massimo Colombo, Sergio Abrignani, Petra Neddermann, Raffaele De Francesco
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138546 (2015)
Hepatitis C virus (HCV) variants characterized by genomic deletions in the structural protein region have been sporadically detected in liver and serum of hepatitis C patients. These defective genomes are capable of autonomous RNA replication and are
Externí odkaz:
https://doaj.org/article/903b408f76e049e38e84d2a4a80f3a45
Autor:
Annalisa Bianco, Veronica Reghellin, Lorena Donnici, Simone Fenu, Reinaldo Alvarez, Chiara Baruffa, Francesco Peri, Massimiliano Pagani, Sergio Abrignani, Petra Neddermann, Raffaele De Francesco
Publikováno v:
PLoS Pathogens, Vol 8, Iss 3, p e1002576 (2012)
4-anilino quinazolines have been identified as inhibitors of HCV replication. The target of this class of compounds was proposed to be the viral protein NS5A, although unequivocal proof has never been presented. A 4-anilino quinazoline moiety is ofte
Externí odkaz:
https://doaj.org/article/0c7408dee75a4019a571d0424fdeb602
Publikováno v:
International Journal of Molecular Sciences. 24:6354
The term “neurodegenerative diseases” (NDs) identifies a group of heterogeneous diseases characterized by progressive loss of selectively vulnerable populations of neurons, which progressively deteriorates over time, leading to neuronal dysfuncti
Autor:
Annalisa Bianco, Sabrina Cicolini, Diana Caroli, Giorgio Bedogni, Alessandro Sartorio, Cristina Bellarosa, Claudio Tiribelli
Publikováno v:
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 10, Iss 2812, p 2812 (2021)
Volume 10
Issue 13
Journal of Clinical Medicine, Vol 10, Iss 2812, p 2812 (2021)
Volume 10
Issue 13
As in adults, obesity also plays a central role in the development of metabolic syndrome (MS) in children. Non-alcoholic fatty liver disease (NAFLD) is considered a manifestation of MS. Not only MS but also NAFLD seem to be inversely associated with
Publikováno v:
Frontiers in Pharmacology
Background: Unconjugated bilirubin (UCB) is more than the final product of heme catabolism. Mildly elevated systemic bilirubin concentrations, such as in Gilbert syndrome (GS), protect against various oxidative stress-mediated and metabolic diseases,
Autor:
Claudio Tiribelli, Annalisa Bianco, Aleš Dvořák, Camille Gironde, Libor Vítek, Nikola Capková, Christophe Furger, Cristina Bellarosa
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 21
International Journal of Molecular Sciences, Vol 21, Iss 8101, p 8101 (2020)
Volume 21
Issue 21
International Journal of Molecular Sciences, Vol 21, Iss 8101, p 8101 (2020)
Background: Severe hyperbilirubinemia can cause permanent neurological damage in particular in neonates, whereas mildly elevated serum bilirubin protects from various oxidative stress-mediated diseases. The present work aimed to establish the intrace
Autor:
Federica Facciotti, Petra Neddermann, Chiara Romagnani, Sergio Abrignani, Paola Gruarin, Svenja Steinfelder, Raffaele De Francesco, Anja Weick, Giulia Nizzoli, Annalisa Bianco, Lorenzo Pignataro, Carmen Scheibenbogen, Jens Geginat, Monica Moro, K Stölzel, Mariacristina Crosti, Bodo Steckel, Sara Torretta, Jana Krietsch
Publikováno v:
Blood. 122:932-942
Dendritic cells (DC) have the unique capacities to induce primary T-cell responses. In mice, CD8α(+)DC are specialized to cross-prime CD8(+) T cells and produce interleukin-12 (IL-12) that promotes cytotoxicity. Human BDCA-3(+)DC share several relev