Conformational properties, membrane interaction, and antibacterial activity of the peptaibiotic chalciporin A

Autor: Barbara Biondi Cristina Peggion Marta De Zotti Chiara Pignaffo Annalisa Dalzini Marco Bortolus Simona Oancea Geta Hilma Annalisa Bortolotti Lorenzo Stella Jens Z. Pedersen Victoria N. Syryamina Yuri D. Tsvetkov Sergei A. Dzuba Claudio Toniolo Fernando Formaggio

Publikováno v: Peptide Science Special Issue: Emerging Peptide Science in Italy (2018): e23083. doi:10.1002/bip.23083
info:cnr-pdr/source/autori:Barbara Biondi Cristina Peggion Marta De Zotti Chiara Pignaffo Annalisa Dalzini Marco Bortolus Simona Oancea Geta Hilma Annalisa Bortolotti Lorenzo Stella Jens Z. Pedersen Victoria N. Syryamina Yuri D. Tsvetkov Sergei A. Dzuba Claudio Toniolo Fernando Formaggio/titolo:Conformational properties, membrane interaction, and antibacterial activity of the peptaibiotic chalciporin A:..../doi:10.1002%2Fbip.23083/rivista:Peptide Science/anno:2018/pagina_da:e23083/pagina_a:/intervallo_pagine:e23083/volume:Special Issue: Emerging Peptide Science in Italy

In this work, an extensive set of spectroscopic and biophysical techniques (including FT-IR absorption, CD, 2D-NMR, fluorescence, and CW/PELDOR EPR) was used to study the conformational preferences, membrane interaction, and bioactivity properties of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::b04d9c1c2a1f2f90d358974be87827fa
https://publications.cnr.it/doc/394993

On the purported 'backbone fluorescence' in protein three-dimensional fluorescence spectra

Autor: Marco van de Weert, Sara Bobone, Saad Tayyab, Noor Hafizan B. Bahring, Annalisa Bortolotti, Lorenzo Stella, Yin How Wong, Stine S. Korsholm

Publikováno v: Bortolotti, A, Wong, Y H, Korsholm, S S, Bahring, N H B, Bobone, S, Tayyab, S, Van De Weert, M & Stella, L 2016, ' On the purported "backbone fluorescence" in protein three-dimensional fluorescence spectra ', RSC Advances, vol. 6, no. 114, pp. 112870-112876 . https://doi.org/10.1039/c6ra23426g

In this study, several proteins (albumin, lysozyme, insulin) and model compounds (Trp, Tyr, homopolypeptides) were used to demonstrate the origin of the fluorescence observed upon their excitation at 220-230 nm. In the last 10 years we have observed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a8109c0dafaccc51ff67b018c50aa27
https://doi.org/10.1039/c6ra23426g

[Cu(TPMA)(Phen)](ClO4)(2): Metallodrug Nanocontainer Delivery and Membrane Lipidomics of a Neuroblastoma Cell Line Coupled with a Liposome Biomimetic Model Focusing on Fatty Acid Reactivity

Autor: Toniolo, Gianluca Louka, Maria Menounou, Georgia Fantoni, Nicolo Zuin Mitrikas, George Efthimiadou, Eleni K. Masi, Annalisa Bortolotti, Massimo Polito, Letizia Bolognesi, Andrea Kellett, Andrew Ferreri, Carla Chatgilialoglu, Chryssostomos

The use of copper complexes for redox and oxidative-based mechanisms in therapeutic strategies is an important field of multidisciplinary research. Here, a novel Cu(II) complex [Cu(TPMA)(Phen)] (ClO4)(2) (Cu-TPMA-Phen, where TPMA = tris-(2-pyridylmet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::353cfb6a22688b2102f01fa8c4b7bc4e
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3181899

Membrane perturbing activities and structural properties of the frog-skin derived peptide Esculentin-1a(1-21)NH

Autor: Maria Rosa, Loffredo, Anirban, Ghosh, Nicole, Harmouche, Bruno, Casciaro, Vincenzo, Luca, Annalisa, Bortolotti, Floriana, Cappiello, Lorenzo, Stella, Anirban, Bhunia, Burkhard, Bechinger, Maria Luisa, Mangoni

Publikováno v: Biochimica et biophysica acta. Biomembranes. 1859(12)

Antimicrobial peptides (AMPs) represent new alternatives to cope with the increasing number of multi-drug resistant microbial infections. Recently, a derivative of the frog-skin AMP esculentin-1a, Esc(1-21), was found to rapidly kill both the plankto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7b61200a2c6615ac6787c790ef0ed88f
https://pubmed.ncbi.nlm.nih.gov/28912103

4-Cyano-α-methyl-l-phenylalanine as a spectroscopic marker for the investigation of peptaibiotic-membrane interactions

Autor: Bernard Kaptein, Barbara Biondi, Marta De Zotti, Edoardo Longo, Sara Bobone, Claudio Toniolo, Cristina Peggion, Andrea Dalla Bona, Fernando Formaggio, Annalisa Bortolotti, Lorenzo Stella

Publikováno v: Chemistry & biodiversity
12 (2015): 513–527. doi:10.1002/cbdv.201400404
info:cnr-pdr/source/autori:De Zotti, Marta; Bobone, Sara; Bortolotti, Annalisa; Longo, Edoardo; Biondi, Barbara; Peggion, Cristina; Formaggio, Fernando; Toniolo, Claudio; Dalla Bona, Andrea; Kaptein, Bernard; Stella, Lorenzo/titolo:4-Cyano-alpha-methyl-L-phenylalanine as a Spectroscopic Marker for the Investigation of Peptaibiotic-Membrane Interactions/doi:10.1002%2Fcbdv.201400404/rivista:Chemistry & biodiversity (Print)/anno:2015/pagina_da:513/pagina_a:527/intervallo_pagine:513–527/volume:12

Two analogs of the ten-amino acid residue, membrane-active lipopeptaibiotic trichogin GA IV, mono-labeled with 4-cyano-α-methyl-L-phenylalanine, a potentially useful fluorescence and IR absorption probe of the local microenvironment, were synthesize

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d9dd29098291a12e37f854b535162f
https://pubmed.ncbi.nlm.nih.gov/25879497