Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Annalaura SABATUCCI"'
Autor:
Debora Agata Anzalone, Luca Palazzese, Marta Czernik, Annalaura Sabatucci, Luca Valbonetti, Emanuele Capra, Pasqualino Loi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract The current protocols of in vitro fertilization and culture in sheep rely on paradigms established more than 25 years ago, where Metaphase II oocytes are co-incubated with capacitated spermatozoa overnight. While this approach maximizes the
Externí odkaz:
https://doaj.org/article/f8c0b9dd16604d8a99c0b4135c4f7389
Autor:
Sergio Oddi, Lucia Scipioni, Antonio Totaro, Clotilde Angelucci, Beatrice Dufrusine, Annalaura Sabatucci, Daniel Tortolani, Isabella Coletta, Maria Alessandra Alisi, Lorenzo Polenzani, Michael Assfalg, Carlo Caltagirone, Enrico Dainese, Mauro Maccarrone
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Abstract We investigated the cellular and molecular mechanisms by which bindarit, a small indazolic derivative with prominent anti-inflammatory effects, exerts its immunoregulatory activity in lipopolysaccharide (LPS) stimulated human monocytic cells
Externí odkaz:
https://doaj.org/article/572eb2b99d5749e3b72bf31cc3872ede
Autor:
Cinzia Rapino, Annalisa Castellucci, Anna Rita Lizzi, Annalaura Sabatucci, Clotilde B. Angelucci, Daniel Tortolani, Gianna Rossi, Gabriele D’Andrea, Mauro Maccarrone
Publikováno v:
Molecules, Vol 24, Iss 7, p 1432 (2019)
Endocannabinoid (eCB)-binding receptors can be modulated by several ligands and membrane environment, yet the effect of glycosylation remains to be assessed. In this study, we used human neuroblastoma SH-SY5Y cells to interrogate whether expression,
Externí odkaz:
https://doaj.org/article/60c078fe38584f158a4ba6473d282adc
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2576
In this chapter, we will describe the bioinformatic tools that allow verifying the presence of CpG islands in a gene promoter region. We will also describe the tools needed to identify consensus motifs for specific transcription factors, focusing on
Autor:
Clotilde B, Angelucci, Annalaura, Sabatucci, Ana Lia, Bernardo, Alexandrine, Kurtz, Sergio, Oddi, Enrico, Dainese
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2576
Understanding the correct interaction among the different components of the endocannabinoid (eCB) system is fundamental for a proper assessment of the function of eCBs as signaling molecules. The knowledge of how the membrane environment modulates th
Autor:
Claudio D’Addario, Mariangela Pucci, Fabio Bellia, Antonio Girella, Annalaura Sabatucci, Federico Fanti, Matteo Vismara, Beatrice Benatti, Luca Ferrara, Federica Fasciana, Laura Celebre, Caterina Viganò, Luca Elli, Manuel Sergi, Mauro Maccarrone, Valeria Buzzelli, Viviana Trezza, Bernardo Dell’Osso
Publikováno v:
Clinical epigenetics. 14(1)
Background Obsessive–compulsive disorder (OCD) is a prevalent and severe clinical condition. Robust evidence suggests a gene-environment interplay in its etiopathogenesis, yet the underlying molecular clues remain only partially understood. In orde
Autor:
Enrico Dainese, Clotilde B. Angelucci, Monica Simonetti, Mauro Maccarrone, Daniel Tortolani, Annalaura Sabatucci
Publikováno v:
Cannabis and Cannabinoid Research
Background: Fatty acid amide hydrolase (FAAH) is a membrane-bound homodimeric enzyme that gets in contact with a lipophilic substrate in the lipid bilayer, and then cleaves it into water soluble products. FAAH plays a critical role in modulating in v
Autor:
Emanuele Capra, Luca Palazzese, Annalaura Sabatucci, Debora Agata Anzalone, Luca Valbonetti, Pasqualino Loi, Marta Czernik
Publikováno v:
Scientific Reports
Scientific Reports (Sci Rep)
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports (Sci Rep)
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
The current protocols of in vitro fertilization and culture in sheep rely on paradigms established more than 25 years ago, where Metaphase II oocytes are co-incubated with capacitated spermatozoa overnight. While this approach maximizes the number of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bb953d4af9b489828a1e6bc59367c1d
http://hdl.handle.net/11575/120420
http://hdl.handle.net/11575/120420
Autor:
Beatrice Dufrusine, Sergio Oddi, Gianni De Fabritiis, Filomena Fezza, Mauro Maccarrone, Monica Simonetti, Annalaura Sabatucci, Clotilde B. Angelucci, Enrico Dainese, Alice Ballone
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Fatty acid amide hydrolase (FAAH) is a membrane-bound homodimeric enzyme that in vivo controls content and biological activity of N-arachidonoylethanolamine (AEA) and other relevant bioactive lipids termed endocannabinoids. Parallel orientation of FA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9646d9d64f2430fb4a6efc14ca337b5
Publikováno v:
Biotechnology and Applied Biochemistry. 65:21-28
The recent resolution of the crystal structure of type-1 cannabinoid receptor (CB1 ) and the discovery of novel modulators for this target open the way to the possibility of elucidating the structural requirements for CB1 binding, and thereby facilit